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3-Butylidenephthalide

Product Name: 3-Butylidenephthalide
Synonym: N-BUTYLIDENEPHTHALIDE;FEMA 3333;BUTYLIDENE PHTHALIDE;3-butylidene-1(3h)-isobenzofuranon;3-butylidene-phthalid
CAS NO.: 551-08-6
EINECS NO.: 208-991-3
Molecular Formula: C12H12O2
Purity & Grade: 99%; Medicine grade
Character: liquid
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
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  • Product Description

Xi'an Faithful BioTech Co., Ltd: Your Trusted 3-Butylidenephthalide Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd. sells high-quality 3-Butylidenephthalide. 3-Butylidenephthalide is a natural product derived from plants (such as Angelica sinensis in the Apiaceae family). Its application and research advantages mainly lie in its potential biological activity. Our company focuses on providing high-quality research reagents, ensuring that the purity of our products typically reaches over 98% to meet precise experimental needs. We offer a variety of options from small sizes (such as 5mg, 10mg) to large packages (such as 100mg, 1g or more), and can even customize products according to specific customer requirements. Furthermore, many of our products are readily available, enabling us to provide immediate quotes and fast delivery, ensuring the continuity of research progress.

3-Butylidenephthalide Introduction

3-Butylidenephthalide is a biologically active phthalide compound, a pale yellow oily liquid at room temperature. It is a natural active ingredient extracted from Ligusticum chuanxiong (Ligusticum striatum) and possesses various biological activities, including insecticidal and anti-fibrotic effects, with wide applications in the pharmaceutical, agricultural, and fragrance industries. Studies have shown that this compound improves cerebral microcirculation, has anti-neurotoxic properties, and inhibits neuronal apoptosis, showing potential application value in the treatment of cerebral ischemia and stroke. It exhibits inhibitory effects on proliferation and induces apoptosis in various cancer cell lines (such as glioblastoma, lung cancer, and liver cancer cells). It has anti-inflammatory effects and can inhibit platelet aggregation, contributing to improved cardiovascular health. It can effectively inhibit the growth of certain plant pathogenic fungi and melanin biosynthesis.

Email: sales9@faithfulbio.com

COA

Test itemsSpecificationsResults
AppearanceSlight Yellow LiquidConform
Purity≥98%99.15%
Any other impurity≤2%0.60%
ConclusionConform with enterprise specification

Why Choose Us?

  1. High Purity Guarantee: We promise to provide products that undergo rigorous quality control (QC) testing, with a purity typically exceeding 98% (specific indicators are subject to the actual Certificate of Accounts), ensuring the accuracy and reliability of your experimental results.

  2. Stable Product Batch Sizes: We implement strict production process management to ensure consistent product quality across different batches, facilitating long-term, reproducible research.

  3. In-Stock Inventory and Rapid Response: Maintaining readily available stock allows us to process orders quickly and ship rapidly, minimizing your procurement cycle.

  4. Customized Services: We can provide customized synthesis services with different packaging specifications and even on a larger scale, based on your specific needs.

  5. Refined Logistics and Packaging: We use professional cold chain or light-protected packaging to ensure the stability and activity of 3-Butylidenephthalide during transportation, delivering it safely to you.

Application Areas

  • Potential for Treating Neurological Disorders: In terms of neuroprotection, it can improve cerebral microcirculation and inhibit neuronal apoptosis, showing potential therapeutic and protective effects against stroke (cerebral ischemia) and neurodegenerative diseases (such as spinocerebellar ataxia type 3).

  • Anti-tumor Research: 3-Butylidenephthalide has shown anti-cancer activity in in vitro and animal experiments, inhibiting the proliferation, migration, and invasion of various cancer cells (such as glioblastoma, lung adenocarcinoma, and bladder cancer cells) and inducing apoptosis, and is considered a potential lead compound for cancer chemotherapy products.

  • Anti-inflammatory and Cardiovascular Health: It has anti-inflammatory and antiplatelet aggregation effects, helping to improve cardiovascular health and reduce the risk of thrombosis-related diseases.

  • Antispasmodic and Analgesic: As an active ingredient in traditional herbs such as Angelica sinensis and Ligusticum chuanxiong, it is used to relieve symptoms such as smooth muscle spasms, dysmenorrhea, and abdominal pain.

  • Flavoring Agent: 3-Butylidenephthalide has a unique celery-like, green herbal aroma and flavor, and is used as a natural flavoring agent or flavor enhancer in the food industry.

  • Biological pesticide development: Research has found that 3-Butylidenephthalide has insecticidal and inhibitory effects on various pests (such as the larvae of the beet armyworm) and plant pathogenic fungi, demonstrating its great potential as a natural, environmentally friendly pesticide.

  • Fungal inhibitors: It can effectively inhibit the biosynthesis of melanin in certain fungi, thereby controlling plant diseases.

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FAQ

Q1: What are the sources of 3-Butylidenephthalide?

A1: Its natural sources are primarily extracts from the roots of plants in the Apiaceae family, especially:
Ligusticum chuanxiong Hort.
Angelica sinensis.
It can also be prepared through organic chemical synthesis.

Q2: Is 3-Butylidenephthalide a liquid or a solid?

A2: At room temperature and pressure, pure 3-Butylidenephthalide typically appears as a colorless to pale yellow liquid or oil.

Q3: Does 3-Butylidenephthalide have isomers?

A3: Yes, it exists in two geometric isomers: Z-type and E-type. They differ in their double bond configurations:

E-type (trans): The butenyl group is arranged trans-with the benzene ring.

Z-type (cis): The butenyl group is arranged cis-with the benzene ring.

Contact Us

99%+ high purity 3-Butylidenephthalide, in stock and ready to ship! Dedicated raw material for pharmaceutical R&D, agricultural plant protection, and fragrance formulation. 24-hour order response; contact us now to secure your supply! Please contact my email sales9@faithfulbio.com.

Email: sales9@faithfulbio.com

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