Afatinib dimaleate API
Synonym: BIBW2992 DiMaleate;BIBW2992-MA2;Afatinib (diMaleate);Afatinib (diMaleate), BIBW2992;Afatinib double Maleate;Afatinib (BIBW2992) Dimaleate
CAS NO.: 850140-73-7
EINECS NO.: 810-416-1
Molecular Formula: C28H29ClFN5O7
Purity & Grade: 99%; Medicine grade
Character: White powder
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-10 days
Store & Shelf life: Cool & dry place; 36 months
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Afatinib dimaleate API Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd. sells high-quality Afatinib dimaleate API. As a premium supplier of Afatinib dimaleate, our company boasts several key advantages: complete and compliant qualifications, product purity of 98%-99%, rigorous control of impurities and residues through multiple methods, and traceable quality. We possess strong technical capabilities, with a professional R&D team and innovative synthesis processes, supporting customized synthesis and impurity reference standard services. Flexible production and supply, global logistics with 5-7 day delivery, and temperature-controlled packaging ensures stable supply. Comprehensive and attentive service, providing complete documentation such as COA and MSDS, along with technical support. Leveraging large-scale production and process optimization, our pricing is highly competitive, with tiered discounts for bulk purchases, providing customers with stable, compliant, and cost-effective supply chain solutions.
Afatinib dimaleate API Introduction
Afatinib dimaleate API is a salt of afatinib, an aminotoluidine-substituted quinazoline derivative used to treat cancers and diseases of the respiratory tract, lungs, gastrointestinal tract, bile ducts, and gallbladder. It is an aniline-quinazoline that irreversibly inhibits the activity of EGFR and HER2 kinases. Afatinib dimaleate is an organic synthetic intermediate and pharmaceutical intermediate, used in laboratory research and development processes and in chemical and pharmaceutical synthesis.
COA
| Test items | Specifications | Results |
| Description | Off-white power | Conform |
| Identification | NMR HPLC | Conform |
| Solubility | soluble in DMSO | Conform |
| Water content | ≤0.5% | 0.10% |
| Loss on drying | ≤0.5% | 0.18% |
| Single impurity | ≤0.2% | 0.09% |
| Totle impurites | ≤1.0% | 0.2% |
| Assay | ≥99.0% | 99.8% |
| Conclusion | Conform with enterprise specification | |
Why Choose Us?
Our products maintain a stable purity of 98%-99%, ensuring batch-to-batch consistency through cross-testing using multiple methods including HPLC and NMR. Equipped with professional testing equipment and a dedicated team, each batch undergoes rigorous inspection to prevent raw material quality from affecting experimental or production results.
We support orders of all scales, from milligram-level pilot-scale to kilogram-level pilot-scale to ton-level commercial production, guaranteeing uninterrupted supply. Global 7-10 day fast shipping, professional temperature-controlled packaging and cold chain logistics ensure product stability during transportation and storage.
Through large-scale production and process optimization, we reduce unit costs. Bulk purchases enjoy tiered discounts, and long-term partnerships provide price guarantees. Flexible packaging specifications adapt to your production needs, avoiding breakage and loss, helping you control costs while securing a stable supply of high-quality raw materials.
Application Areas
Afatinib dimaleate is indicated for patients with locally advanced or metastatic squamous cell lung cancer whose disease has progressed during or after platinum-based chemotherapy.
Afatinib dimaleate exerts its antitumor effect by irreversibly binding to and inhibiting the tyrosine kinase domain of the ErbB receptor family, thereby blocking signaling pathways required for cancer cell growth.
Afatinib dimaleate is being investigated for the treatment of other types of cancer, such as breast cancer, pancreatic cancer, liver cancer, kidney cancer, thyroid cancer, gastrointestinal stromal tumors, and colorectal cancer.
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FAQ
Q1: What is Afatinib dimaleate API used for?
A1: A product used to treat certain types of non-small cell lung cancer that have spread to other parts of the body.
Q2: How does Afatinib dimaleate API work?
A2: Afatinib dimaleate API is a called a cancer growth blocker. It blocks the signals (messages) of particular proteins that tell a cancer to divide and grow. So this can help slow down or stop the cancer growing.
Q3: What are the side effects of Afatinib dimaleate API?
A3: Bloody or cloudy urine.
burning, dry, or itching eyes.
diarrhea.
difficult, burning, or painful urination.
discharge or excessive tearing.
fever.
frequent urge to urinate.
redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid.
Contact Us
Instantly connect to the Afatinib dimaleate API direct supply channel! Contact us now to lock in preferential pricing and delivery timelines, and enjoy worry-free procurement without waiting! Please contact my email sales9@faithfulbio.com.
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