Candesartan Cilexetil API
Synonym: Candesantan Cilexetil;tcv116
CAS NO.: 145040-37-5
EINECS NO.: 627-030-2
Molecular Formula: C33H34N6O6
Purity & Grade: 99%; Medicine grade
Character: White powder
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-10 days
Store & Shelf life: Cool & dry place; 36 months
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Candesartan Cilexetil API Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd. sells high-quality Candesartan Cilexetil API. Our company boasts large-scale production facilities, ensuring a stable and continuous supply of Candesartan cilexetil powder. We can also rapidly increase production capacity to meet market demand during periods of shortage. Our products meet international standards and possess all necessary certifications, guaranteeing high purity and consistency. Furthermore, we have strong R&D capabilities, enabling us to optimize production processes, increase yields, reduce costs, and address increasingly stringent environmental requirements.
Candesartan Cilexetil API Introduction
Candesartan Cilexetil API is a high-purity, standardized angiotensin II receptor antagonist (ARB) active pharmaceutical ingredient (API). As a core ingredient in widely used first-line antihypertensive products globally, its powder form offers key advantages such as strong process adaptability, high stability, and controllable bioavailability, making it widely used in formulation research and large-scale production. Candesartan cilexetil is rapidly hydrolyzed in vivo into its active metabolite, Candesartan. Candesartan is a selective angiotensin II receptor (AT1) antagonist, antagonizing the vasoconstrictive effects of angiotensin II by binding to AT1 receptors in vascular smooth muscle, thereby reducing peripheral vascular resistance.
COA
| Test items | Specifications | Results |
| Appearance | A white or almost white powder | White powder |
| Identification-IR | Complies with the reference spectrum | Complies |
| Identification-UV | Maximal absorptions at 254nm, minimum absorption at 242nm | Complies |
| Water | ≤0.3% | 0.19% |
| Residual solvents | ||
| Methanol | ≤3000ppm | Not found |
| Ethanol | ≤5000ppm | Not found |
| Ethyl ether | ≤5000ppm | 68ppm |
| Acetone | ≤5000ppm | 482ppm |
| Ethyl acetate | ≤5000ppm | Not found |
| Dichloromethane | ≤600ppm | Not found |
| Dimethylformamide | ≤880ppm | Not found |
| Related substances | ||
| Impurity A | ≤0.15% | <0.05% |
| Impurity B | ≤0.3% | <0.05% |
| Impurity F | ≤0.2% | <0.05% |
| Impurity G | ≤0.2% | <0.05% |
| Impurity H | ≤0.15% | Not found |
| Other individual impurity | ≤0.10% | 0.04% |
| Total impurities | ≤0.6% | 0.21% |
| Sulfated ash | ≤0.1% | 0.06% |
| Heavy metals | ≤10ppm | <10ppm |
| Assay(Dried substance) | 99.0~101.0% | 99.8% |
| Conclusion | Conform with enterprise specification | |
Why Choose Us?
High Quality Consistency: Every batch of product undergoes rigorous quality control and comprehensive analytical testing (providing detailed CoA) to ensure batch-to-batch consistency and reduce the risks associated with your formulation production.
Large-Scale Production Capacity Guarantee: We possess a modern production facility capable of meeting orders ranging from small-batch needs in the R&D stage to large-scale orders for commercial production.
Continuous and Stable Supply: We offer reliable long-term supply agreements, minimizing the risk of production disruptions due to raw material shortages.
Efficient Logistics System: Mature warehousing and logistics solutions ensure products remain in optimal condition during transportation and are delivered on time.
Application Areas
Hypertension: This is the most widespread and primary application of Candesartan cilexetil. It lowers blood pressure by blocking angiotensin II receptors, helping blood vessels relax and dilate.
Heart Failure: Candesartan cilexetil is suitable for treating symptomatic chronic heart failure, especially for patients intolerant to angiotensin-converting enzyme inhibitors (ACEIs), or as adjunctive therapy to ACEIs.
Nephroprotection (partial research and application): Candesartan cilexetil has a certain nephroprotective effect in patients with diabetic nephropathy or chronic kidney disease caused by hypertension, helping to slow the deterioration of kidney function.
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FAQ
Q1: What is Candesartan Cilexetil API?
A1: Candesartan cilexetil is a white to off-white crystalline powder and a precursor to Candesartan. It is inactive on its own but rapidly hydrolyzes in vivo to the active form of Candesartan after absorption.
Q2: What are the common impurities in Candesartan Cilexetil API?
A2: Common impurities include intermediates from the production process, degradation products (such as free candesartan acids), and residual process solvents.
Q3: What are the storage requirements for Candesartan Cilexetil API?
A3: Candesartan cilexetil powder is sensitive to light and moisture. It is generally recommended to store it in a tightly closed container in a cool, dry place away from light, at a temperature generally below 25°C to ensure its stability.
Contact Us
The global cardiovascular product market is growing at 12.3% annually, and your Candesartan Cilexetil API supply is ready! All compliance certifications are complete. Contact us now! Please contact my email sales9@faithfulbio.com.
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