Cisatracurium besilate

Xi'an Faithful BioTech Co., Ltd: Your Trusted Cisatracurium besilate Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd was founded in 2018 with core product Cisatracurium besilate. We specialize in high-end muscle relaxant raw materials. The product purity is stably controlled at over 99.0%, and the impurity control level is better than the current pharmacopoeia standards. We have provided long-term supply services to over 50 domestic and foreign pharmaceutical companies and buyers, and our products are exported to mainstream regulatory markets such as Europe, America, and India.

Cisatracurium besilate Introduction

Cisatracurium besilate is a moderately effective, non depolarizing benzylisoquinoline based skeletal muscle relaxant. It is a single cis isomer of Atracurium besylate, with a muscle relaxant efficacy approximately 4-5 times that of Atracurium besylate. The biggest clinical advantage of this product is that its metabolic pathway does not rely on the liver and kidneys, and is mainly eliminated through Hofmann degradation in plasma. It has minimal cardiovascular impact and no significant histamine release effect. It is currently one of the safer muscle relaxants in clinical anesthesia.

Specifications

Application area of Cisatracurium besilate

• Surgical anesthesia: As an adjuvant medication for general anesthesia, it provides skeletal muscle relaxation in various surgeries (such as general surgery, thoracic and abdominal surgery), facilitating tracheal intubation and maintaining intraoperative muscle relaxation.
• Intensive care treatment: Used in ICU for critically ill patients who require mechanical ventilation, to improve ventilation efficiency and reduce human-machine confrontation by relaxing skeletal muscles.
• Day surgery and inpatient surgery: Due to their fast recovery speed, they are suitable for both day surgeries that require quick turnover and large surgeries that require long-term hospitalization.
• Pediatric anesthesia: According to the drug marketing information, this product is suitable for children aged 1 month and above as a muscle relaxant during surgery or operation.
• Preparation production: As an active pharmaceutical ingredient, it is mainly supplied to major pharmaceutical factories for the production of Cisatracurium besilate injection or freeze-dried powder injections for injection.

Main Advantages

1. High safety: It has extremely low histamine release, rarely causes hypotension or bronchospasm in clinical use, has a weak impact on heart rate, and significantly improves cardiovascular stability during anesthesia induction.
2. Low liver and kidney dependence: Cisatracurium besilate is mainly eliminated through Hofmann non enzymatic degradation, not affected by age or liver and kidney function. This has irreplaceable clinical advantages for the special patient population with liver and kidney dysfunction.
3. Strong controllability: rapid onset, moderate duration of action, and high predictability of recovery. After stopping the administration, neuromuscular function can quickly and naturally recover, and can also be rapidly antagonized by anticholinesterase inhibitors.
4. Metabolic stability: As a high-purity raw material, its specific crystal structure gives it good chemical stability, making it easy to store and transport for a long time.

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Why choose us

We implement stricter internal control standards than CP/EP/USP, with product purity reaching over 99.0% and single impurities controlled below 0.1%; We have long-term safety stock. Whether you need kilogram level samples or more commercial orders, we can promise to deliver on time and address the risk of supply disruptions. By optimizing the crystallization purification process, our cooperative factory has effectively controlled production costs. We are committed to providing our customers with a highly competitive pricing system to help you gain an advantage in the fierce terminal market competition.

Quality Control

R&D Results

Packaging and Transportation

After-Sales Service

Qualification Certification

Exhibition

FAQ

Q1:What is the difference between Cisatracurium besilate and regular pheniramate?

A1:Cisatracurium besilate is a single cis enantiomer of Atracurium besilate, and its muscle relaxant efficacy is 4-5 times that of regular Atracurium besilate. The biggest difference is that Cisatracurium besilate causes almost no histamine release at clinical doses and has minimal impact on blood pressure and heart rate, while regular atracurium may cause hypotension and tachycardia at high doses.

Q2:What is the minimum order quantity (MOQ)? Can samples be provided?

A2:We support flexible collaboration models. The minimum order quantity for commercial orders is usually 1 kilogram, but we encourage potential customers to contact us to apply for samples for testing. The sample size usually supports R&D or validation needs of 10-100g.

Q3:What are the special requirements for the storage environment of this active pharmaceutical ingredient?

A3: This raw material has certain hygroscopicity and sensitivity to temperature. It is usually recommended to store in a sealed, moisture-proof, dark, and controlled room temperature environment of 15-30 ℃。

Contact US

We look forward to building a safe line of defense for anesthesia with high-quality Cisatracurium besilate raw powder. You can contact us sales1@faithfulbio.com.