Dexibuprofen API

Xi'an Faithful BioTech Co., Ltd: Your Trusted Dexibuprofen API powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a supplier of Dexibuprofen API, specializing in the production and foreign trade sales of scientific research chemical reagents, intermediates, fine chemicals, food additives, and plant extracts. We adhere to the corporate philosophy of "quality as life, technology as the guide, innovation for survival, and integrity-based", and insist on the corporate philosophy of "unity and hard work, courage to innovate, excellence, and cooperative development". We sincerely cooperate with overseas colleagues for mutual benefit and win-win cooperation.

Dexibuprofen API powder Introduction

(S)-(+)-Ibuprofen,a S (+) - enantiomer of Ibuprofen is an effective COX-1 and COX-2 inhibitor with IC50 values of 2.1 μ M and 1.6 μ M, respectively. (S) - (+) - Ibuprofen has analgesic, anti-inflammatory, anticancer, and antipyretic effects. It can exert pharmacological activity by inhibiting the synthesis of prostaglandins (PG). The appearance is white powder. From the perspective of chemical structure, S-ibuprofen is a chiral derivative of naphthylacetic acid. Chiral compounds refer to their molecules that exist in mirror isomers, which cannot coincide with each other through rotation or rotation. The mirror isomers of chiral molecules are called enantiomers, which have the same chemical formula but different spatial structures. Our Dexibuprofen API undergoes strict quality control, resulting in a final product purity of over 99%.

Specifications

 Why Choose Us?

High purity and low impurities: Adopting advanced chiral separation technology, the product purity is ≥ 99.5%, optical purity is ≥ 99%, total impurities are ≤ 0.5%, and relevant substances (such as ibuprofen impurities A and B) are strictly controlled to meet international pharmacopoeia standards, ensuring the stability and efficacy of the formulated product.
Industry leading bioavailability: D-ibuprofen is the active isomer of ibuprofen, with an oral absorption rate of over 85% (higher than 70% of racemic ibuprofen), and a bioavailability increase of over 30%
Adequate and flexible production capacity: With a large annual production capacity, it can meet large-scale orders (ton level procurement) and support small-scale trial production (kilogram level orders), adapting to the research and development, pilot testing, and commercial production needs of different customers with short delivery cycles.

Main applications

Dexibuprofen API has following uses:
1. Core raw materials for pharmaceutical preparations (mainstream application scenarios)
Antipyretic and analgesic preparations: used for the development of oral tablets, capsules, suspensions, etc., targeting fever caused by common cold/flu in adults and children, as well as mild to moderate pain such as headache, toothache, joint pain, dysmenorrhea, etc., with fast onset (reaching peak blood concentration 1-2 hours after oral administration) and significant analgesic and anti-inflammatory effects.
Anti inflammatory preparations: As first-line treatment materials for autoimmune diseases such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, they can effectively reduce joint redness, pain, and stiffness symptoms, improve patient mobility, and have better gastrointestinal tolerance than traditional Ibuprofen racemates.
Raw materials for external preparations: used for the production of gel, creams, liniments and other external products, which directly act on local pain parts (such as muscle strain, sprain, strain), play an anti-inflammatory and analgesic role through skin penetration, avoid systemic side effects of oral administration, and are applicable to a wider range of people.
2. Health products/functional food ingredients (potential market)
Used for developing sports nutrition supplements (such as post race muscle recovery drinks, fatigue relieving capsules) to help alleviate post exercise muscle soreness, accelerate tissue repair, and is suitable for fitness enthusiasts, athletes, and manual laborers.
As a functional ingredient for "mild analgesia+anti-inflammatory", it is added to dietary supplements for middle-aged and elderly people to assist in improving joint discomfort. Due to its high safety, it can be taken in moderation for a long time.
3. Application in the field of veterinary medicine (segmented market)
Used for the production of pet specific antipyretic and anti-inflammatory drugs (such as dog and cat cold fever, joint inflammation, postoperative pain relief preparations), with low toxicity and good animal tolerance, in line with the development trend of "safe and efficient" pet medicine.

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FAQ

Q1:Is dexibuprofen better than ibuprofen?

A1:Dexibuprofen is as effective and tolerable as ibuprofen. A dose of 5 mg kg−1 and 7 mg kg−1 dexibuprofen in place of 10 mg kg−1 ibuprofen would be sufficient to control fever caused by URTI in children.

Q2:What is another name for Dexibuprofen?

A2:Dexibuprofen is also called (S)-(+)-ibuprofen. Ibuprofen is an α-arylpropionic acid used largely in the treatment of rheumatoid arthritis and widely used over-the counter drug for headache and minor pains. This drug has a chiral center and exists as a pair of enantiomers.

Q3: Can Dexibuprofen dissolve in water?

A3:Dexibuprofen is a chiral phenylacetic acid compound that is only slightly soluble in water. The mass of ibuprofen dissolved in 1 ml of water is less than 1 mg (<1 mg/mL), but it is soluble in a mixture of water and alcohol.

Contact Us

We are not only a supplier of Dexibuprofen API, but also a "product value partner" for our customers. If you need further information on product testing reports, cooperation policies, or samples, please feel free to contact us at any time sales12@faithfulbio.com.