G418 sulfate
CAS NO.: 108321-42-2
Molecular formula:C20H42N4O14S
EINECS:600-864-4
Synonyms:Geneticin
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 100g
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted G418 sulfate Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd has been deeply involved in the field of antibiotic screening for many years, providing core raw materials such as G418 sulfate for biopharmaceuticals, research institutions, and diagnostic companies. Adhering to the principle of putting people first and prioritizing customer needs, we provide solid support for your stable cell line construction and gene editing experiments.
G418 sulfate Introduction
G418 sulfate is an aminoglycoside antibiotic that blocks protein synthesis by inhibiting the elongation step of the 80S ribosome in eukaryotic cells. It is widely used in the field of molecular genetics and is the most commonly used resistance reagent for stable transfection screening. Our G418 sulfate has been carefully selected and has excellent quality and purity, making it the preferred raw material for scientific research.
Specifications
Items | Specification | Result |
Appearance | White powder | White powder |
Assay | ≥450μg/mg | 778μg/mg |
Moisture | ≤12% | 9.1% |
Carbon | 30%-35.4% | 34.2% |
Nitrogen | 7.8-8.4% | 8.2% |
Conclusion: | This batch product conform to the requirements. | |
Application area of G418 sulfate
- Used for screening eukaryotic cell transfection lines carrying neo resistance genes and establishing monoclonal stable cell lines.
- Used for gene knockout, gene insertion, and screening of transgenic animal models.
- Suitable for protoplast transformation screening of microorganisms such as dermatophytes and Fusarium oxysporum.
- Research has shown that it has inhibitory effects on dengue virus and other viruses, and is used to explore the mechanism of antiviral drugs.
Main Advantages
- Accurate screening: G418 sulfate screening has higher efficiency and lower escape rate, reducing the screening time for false positive clones.
- Broad spectrum applicability: suitable for various host cell systems such as mammals, yeast, plants, and protozoa.
- High activity: High purity raw materials (≥ 98%) can reduce the effective working concentration by 15-30%, saving experimental costs.
Contact us sales1@faithfulbio.com or Whats App：+86 17782784795
Why choose us
Uncompromising quality
- While others may chase lower prices, we stay firmly anchored to quality as our true differentiator. Each lot of G418 sulfate comes with rigorous quality clearance—covering activity tests and purity assays—to give you full confidence in quality.
Responsive supply
- From gram-level trial samples to ton-scale production deliveries, we adapt to your evolving needs. Our multi-channel procurement strategy acts as a safety net, ensuring you never face shortages—even when the global supply chain faces disruptions.
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FAQ
Q1:What is the working principle of G418 sulfate？
A1:Based on the neomycin resistance gene (neo) encoding aminoglycoside phosphotransferase, cells expressing this gene acquire resistance and survive in selective culture medium.
Q2:How to determine the appropriate G418 sulfate screening concentration for my cell line?
A2:Suggest conducting a "kill curve" experiment: Inoculate untransfected cells into a 24 well plate, add different concentrations of G-418 (such as 0, 200, 400, 600, 800 µ g/mL), observe for 7-10 days, and use the lowest concentration that can completely kill all cells as the standard.
Q3:Can G418 sulfate be used together with puromycin?
A3:Okay. Two antibiotics can be used for the construction of multiple stable cell lines.
Contact US
We keep G418 sulfate in stock, contact us sales1@faithfulbio.com or Whats App：+86 17782784795 any time .
