Indole-3-propionamide

Xi'an Faithful BioTech Co., Ltd: Your Trusted Indole-3-propionamide Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is supplying high-quality Indole-3-propionamide, we always adhere to the corporate philosophy of "integrity-based, service-oriented", relying on excellent geographical location and first-class technology and logistics resources to provide the highest quality products and services for domestic and foreign customers.

Indole-3-propionamide Introduction

Indole-3-propionamide is a white crystalline powder. Its structure consists of an indole ring and a three carbon side chain with an amide functional group. As an important heterocyclic amide compound, it has unique ion channel regulation ability and can serve as a regulator of various kinases and receptors. Due to its excellent biological activity and structural modifiability, it is a key tool molecule in the fields of medicinal chemistry and life science research.

Specifications

Application area of Indole-3-propionamide

• Ionic channel regulation research: As a small molecule regulator of voltage-gated sodium ion channels (such as hNav1.7 subtype), it is used for pain mechanism and neuroscience research.
• Enzyme inhibitor development: As an inhibitor of histone deacetylase and monoamine oxidase, applied in epigenetics and neurotransmitter metabolism research.
• Complex intermediate synthesis: As a precursor for synthesizing more complex bioactive molecules, it is used to construct new compounds with anti-inflammatory, anticancer, or antibacterial potential.
• Pharmaceutical chemistry research and development: serving as the core framework for optimizing lead compounds, used to improve the affinity and metabolic stability of drugs with biological targets.

Main Advantages

1. Efficient target selectivity: It has a significant inhibitory effect on the hNav1.7 sodium channel subtype and exhibits high activity in cellular electrophysiological experiments, with selectivity superior to traditional ion channel modulators.
2. Good structural modifiability: Multiple modification sites on the indole ring and side chain amide functional groups make it easy to derivatize, making it an ideal framework for pharmaceutical chemists to study structure-activity relationships.
3. Unique dual mechanism of action: Indole-3-propionamide combines the dual characteristics of a TRP ion channel agonist and a specific enzyme inhibitor, providing a unique tool for multi-target drug design and mechanism exploration.

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Why choose us

• Source direct procurement: We deeply bind with upstream raw material manufacturers that have passed GMP certification to ensure stable synthesis routes and clear impurity spectra of our products. Each batch of products is tested by HPLC, with purity ranging from 97% to over 99%.
• Flexible supply chain: We have a regular stock of hundred gram grade spot goods. Support flexible customization from 100mg scientific research small packaging to kilogram level pilot scale packaging;
• Cost advantage: Through large-scale centralized procurement and long-term stable order volume, we have effectively reduced intermediate circulation costs. Compared to scattered procurement, we can offer supply prices 5% -10% lower than the market average to help you reduce the cost of R&D material consumption.

1. Quality Control

R&D Results

Packaging and Transportation

After-Sales Service

Qualification Certification

Exhibition

FAQ

Q1:What is the difference between Indole-3-propionamide and 1H-indole-3-propylamine?

A1:They have different chemical structures and uses. The side chain end of Indole-3-propionamide is an amide group (- CONH ₂), while the side chain end of 1H-indole-3-propylamine is an amine group (- NH ₂). The former is commonly used in channel regulation and enzyme inhibition research, while the latter is mostly used as an intermediate in the synthesis of antidepressants and other drugs.

Q2:What is the solubility of Indole-3-propionamide in buffer solution?

A2:Due to the strong hydrophobicity of indole ring, the solubility of this product in water is relatively low. It is generally recommended to prepare a high concentration stock solution using a solvent first, and then dilute it to the working concentration using a buffer or culture medium.

Q3:How should I store the received goods?

A3: Indole-3-propionamide has a certain degree of moisture absorption, and it is recommended to store it sealed, away from light, and dry at -20 ° C.

Contact US

Contact us sales1@faithfulbio.com at any time if you need more information of Indole-3-propionamide.