Metyrapone powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Metyrapone powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd was founded in 2018 with core product Metyrapone powder.The product purity is stably controlled at over 99.0%, and the impurity control level is better than the current pharmacopoeia standards. We have provided long-term supply services to over 50 domestic and foreign pharmaceutical companies and buyers, and our products are exported to mainstream regulatory markets such as Europe, America, and India.

Metyrapone powder Introduction

Metyrapone Powder is a cortisol synthesis inhibitor, appearing as a white to off-white powder with a raw material purity ≥99.5%. This substance selectively inhibits the activity of adrenal cortex 11β-hydroxylase, blocking the cortisol production pathway. Clinically, it is widely used for the diagnosis and treatment of Cushing's syndrome and for testing hypothalamic-pituitary-adrenal axis function. The raw material has strict impurity control, stable physicochemical properties, and no significant deliquescence or deterioration issues, making it suitable for preclinical pharmacological trials, formulation development, and research on endocrine-related targets.

Specifications

Applications of Metyrapone powder

Metyrapone is primarily used in pharmaceutical manufacturing and clinical diagnostics, specifically including:

• Cushing's Syndrome Treatment: Used for the treatment of endogenous Cushing's syndrome, suitable for preoperative preparation, replacement therapy after surgical failure, and long-term maintenance therapy.
• Endocrine Function Diagnosis: As an ACTH reserve function assay, used for assessing hypothalamic-pituitary-adrenal axis function and differential diagnosis of ACTH-dependent Cushing's syndrome.
• Neuroscience Research: As an 11β-hydroxylase inhibitor, used to study the mechanisms of action of glucocorticoids in neurological diseases such as cerebral ischemia, epilepsy, and anxiety.
• Depression Research: By inhibiting cortisol synthesis, used to study the association between HPA axis dysfunction and mood disorders.

Main Advantages

1. Unique Mechanism of Action: As a specific inhibitor of 11β-hydroxylase, it effectively blocks cortisol synthesis, directly targeting the pathological core of Cushing's syndrome.
2. Rapid Onset of Action and Definite Efficacy: It takes effect approximately 2 hours after oral administration. Clinical studies show that 50-70% of patients achieve satisfactory cortisol level control.
3. High Purity and Controllable Quality: The finished product purity can reach over 98%, meeting USP/EP pharmacopoeia standards, with a complete impurity profile and excellent batch-to-batch consistency.
4. Wide Range of Applications: It serves as a therapeutic drug, a diagnostic reagent, and an important tool in neuroendocrine research, with stable market demand.

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Why choose us

We implement stricter internal control standards than CP/EP/USP, with product purity reaching over 99.0% and single impurities controlled below 0.1%; We have long-term safety stock. Whether you need kilogram level samples or more commercial orders, we can promise to deliver on time and address the risk of supply disruptions. By optimizing the crystallization purification process, our cooperative factory has effectively controlled production costs. We are committed to providing our customers with a highly competitive pricing system to help you gain an advantage in the fierce terminal market competition.

Quality Control

R&D Results

Packaging and Transportation

After-Sales Service

Qualification Certification

Exhibition

FAQ

Q1: Does the purity and impurity levels of Metyrapone Powder meet the standards for research-grade pharmaceuticals?

A1: The Metyrapone Powder supplied by us maintains a purity consistently above 99.5%. Related substances, heavy metals, and residual solvents are strictly controlled, with minimal batch-to-batch variation. Each batch comes with a complete Certificate of Analysis (COA) report, fully meeting the requirements for endocrine target research and preclinical trials.

Q2: This product acts on the adrenal cortex pathway; is its pharmacological effect stable and controllable?

A2: This raw material specifically inhibits 11β-hydroxylase, precisely blocking the cortisol synthesis pathway. Its mechanism of action is mature and stable, with uniform regulatory effects on adrenal hormones, ensuring stable and reproducible experimental data for Cushing's syndrome models.

Q3: Is the Metyrapone Powder easy to store, weigh, and use in experiments?

A3: This product has a dry and fine powder with good flowability. It is not easy to absorb moisture and clump. It has stable physicochemical properties and can be stored at room temperature away from light. It is convenient and uniform to feed, which can reduce the error of raw materials. It is suitable for use in various animal modeling and prescription research and development.

Contact US

We look forward to building a safe line of defense for anesthesia with high-quality Metyrapone Powder. You can contact us allen@faithfulbio.com.