PGE2 API powder
Synonym: Dinoprostone;l-5-heptenoicaci;l-pge2;l-prostaglandine2;prostin
CAS NO.: 363-24-6
EINECS NO.: 206-656-6
Molecular Formula: C20H32O5
Purity & Grade: 99%; Medicine grade
Character: White powder
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-10 days
Store & Shelf life: Cool & dry place; 36 months
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted PGE2 API powder Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd. sells high-quality PGE2 API powder. Our PGE2 powders typically boast an analytical purity exceeding 93% (HPLC), with minimal impurities, ensuring consistency between product efficacy and experimental results. Our products undergo rigorous stability testing, and we provide appropriate storage recommendations (usually -20°C) to guarantee activity and stability during transportation and storage. Furthermore, we possess robust production and supply chain capabilities to meet diverse needs, ranging from research and development applications (milligram-level) to large-scale production (kilogram-level). Products are typically accompanied by Certificates of Analysis (CoA) and other documentation, demonstrating compliance with quality and specifications.
PGE2 API powder Introduction
PGE2 API powder is a white to off-white solid, a natural prostaglandin (PG). It has a contractile effect on the uterus at all stages of pregnancy, but the sensitivity of the uterus to PGE2 varies at different stages, with the term uterus being the most sensitive. It can act directly on the smooth muscle of the uterus, stimulating the smooth muscle of the pregnant uterus to produce uterine contractions similar to those of term labor; it can also directly soften the cervix, facilitating cervical dilation. Prostaglandin E2 can also cause contractions of gastrointestinal smooth muscle and can also act on vascular smooth muscle. Prostaglandin E2 can be used for inducing labor, mid-trimester induction of labor, therapeutic abortion, and preoperative cervical dilation. A few people may experience chills, vomiting, and mild diarrhea, which usually subside spontaneously within a short time or are easily controlled with symptomatic treatment.
COA
| Test items | Specifications | Results |
| Appearance | White to off-white crystalline powder | Complies |
| Identification | HPLC retention time corresponds to the reference standard. | Complies |
| Assay | ≥99.5% | 99.9% |
| Loss on drying | ≤0.1% | 0.05% |
| Sulfated Ash | ≤0.2% | 0.05% |
| Heavy metals | ≤10ppm | 2ppm |
| Related Substances (HPLC) | Total impurities ≤2.5% | 1.5% |
| Individualimpurity≤0.25% | 0.12% | |
| Microbial Limits | TotalAerobic Count:<1000 CFU/g | <100 CFU/g |
| Yeast &Moulds:<100 CFU/g | <10 CFU/g | |
| E.Coli Negative | Negative | |
| Salmonella Negative | Negative | |
| Conclusion | Conform with enterprise specification | |
Why Choose Us?
Superior Product Purity: We offer high-purity PGE2 powder, typically exceeding 98% purity with minimal impurities, ensuring accurate and consistent experimental results. We employ advanced analytical techniques (such as HPLC, MS, and NMR) to verify the purity and structure of each batch.
Excellent Product Stability: PGE2 is prone to discoloration and degradation in liquid environments. Our products are supplied in stable powder form and utilize special packaging to maintain product integrity, ensuring activity and stability during transportation and storage.
Diverse Applications: Our PGE2 products are widely used in various research fields, including inflammation research, bone formation, vasodilation, fertility research, and hematopoietic stem cell (HSC) expansion and transplantation research.
Reliable Supply Chain Capabilities: As a reputable supplier, we possess stable production and supply capabilities to meet diverse needs, from small-scale R&D to large-scale production.
Application Areas
Induction of labor and promotion of delivery: PGE2 is an effective uterine contraction agent. Synthetic PGE2 (dinoprostone) is used to induce labor at or near term of pregnancy by promoting cervical ripening (softening and dilation) and inducing uterine contractions to initiate or accelerate the labor process.
Treatment of male erectile dysfunction: Although not as commonly used as PGE1 (prostaglandin), PGE2 has also been studied or used to treat male erectile dysfunction.
Bone and Bone Metabolism Research: PGE2 plays a crucial role in the balance between bone formation and bone resorption. It is used to study processes such as osteoporosis, fracture healing, and alveolar bone remodeling.
Immunological Research: PGE2 regulates the function of immune cells, including inhibiting the activity of certain T cells and regulating dendritic cell function, making it a key reagent in the study of immune regulation and autoimmune diseases.
Cardiovascular Research: PGE2 has vasodilatory effects and is used to study blood pressure regulation, vascular diseases, and cardioprotective mechanisms.
Stem Cell Research and Applications: PGE2 has become a key additive in stem cell culture media.
Hematopoietic Stem Cell (HSC) Expansion: Studies have shown that PGE2 can significantly promote the in vitro expansion and in vivo transplantation efficiency of hematopoietic stem cells, improving the success rate of bone marrow transplantation.
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FAQ
Q1: What does PGE2 API powder do?
A1: Prostaglandin E2 (PGE2) is a lipid molecule that regulates many vital bodily functions, primarily acting as a key mediator in inflammation, pain, and fever, but also playing crucial roles in reproduction (inducing labor/ripening cervix), vascular tone (vasodilation/constriction), gastrointestinal health, and immune response, often through its four EP receptors. It promotes tissue repair, influences neuronal function, and supports hematopoietic recovery, but its overproduction is linked to diseases like cancer and inflammatory bowel disease.
Q2: What is the difference between PGE1 and PGE2 API powder?
A2: Prostaglandin E1 (PGE1) and E2 (PGE2) are ligands for the prostaglandin E2 receptor (EP) family, which consists of four subtype receptors, designated as EP1, EP2, EP3 and EP4. Interestingly, PGE2 mediates inflammation whereas PGE1 acts as an anti-inflammatory factor.
Q3: What does low PGE2 API powder mean?
A3: PGE2 is produced by the body in response to various stimuli and is known to have both pro-inflammatory and anti-inflammatory effects, depending on the context in which it is produced. A low level of prostaglandin E2 may indicate a decrease in its production or activity in the body.
Contact Us
Peak season stocking countdown! PGE2 API powder capacity is tight, place your order in advance for priority production! Contact us as soon as possible to purchase and ensure your production schedule remains uninterrupted! Please contact my email sales9@faithfulbio.com.
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