Pyrithione Zinc Powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Pyrithione Zinc Powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd specializes in specialty active pharmaceutical ingredients such as Pyrithione Zinc Powder, focusing on the supply of high-quality pharmaceutical raw materials and intermediates, providing stable and compliant Edoxaban for pharmaceutical companies, and helping customers achieve value transformation from research and development to commercialization.

Pyrithione Zinc Powder Introduction

Pyrithione Zinc Powder is a coordination compound formed by zinc ions and pyrithione ligands, with the molecular formula C₁₀H₈N₂O₂S₂Zn and a molecular weight of 317.72. It is a grayish-white to off-white powder with a melting point of 240-250°C, is sparingly soluble in water, and belongs to the class of antibacterial and antifungal agents. Its antibacterial mechanism is believed to be through disrupting the fungal membrane transport system by blocking the proton pump, while simultaneously increasing the intracellular copper ion level in fungal cells and damaging iron-sulfur cluster proteins, thereby inhibiting fungal metabolism and growth.

Specifications 

Application area of Pyrithione Zinc Powder​​​​​​​

Pyrithione Zinc Powder has wide applications in the daily chemical, pharmaceutical, and industrial fields, specifically including:

• Anti-dandruff shampoos and conditioners: As a core active ingredient in anti-dandruff shampoos, it effectively inhibits the growth of scalp fungi such as Malassezia, and is a common solution for oral dandruff problems in over 40% of adults worldwide. The commonly used concentration in OTC products is 1%-2%.
• Skin care products: Used to treat skin diseases such as seborrheic dermatitis, eczema, athlete's foot, atopic dermatitis, tinea versicolor, and vitiligo. Commonly found in OTC creams, lotions, and soaps.
• Paint and plastic fungicides: Added as an antifungal and fungicide to outdoor paints, adhesives, and plastic products to prevent the growth of mold and algae. Used in marine antifouling paints to prevent crustacean adhesion.
• Agricultural fungicide applications: Used in the preparation of fungicides to control bacterial diseases such as citrus Huanglongbing (HLB), exhibiting good inhibitory effects against Gram-negative bacteria.
• Scientific tool compounds: As KMD5A inhibitors and antibacterial and antifungal tools, they are used in basic research on ion channels, microbiology, etc.

Main Advantages

Pyrithione Zinc possesses broad-spectrum antibacterial properties, exhibiting excellent inhibitory effects against fungi that cause dandruff, as well as various common molds and Gram-negative bacteria. The desired efficacy can be achieved with relatively low dosage, resulting in a more cost-effective formulation. Chemically stable within a suitable pH range, Pyrithione Zinc Powder is water-resistant and its activity is not easily lost after washing, providing outstanding long-lasting protection. The color, particle size, and effective content of the powder vary very little between batches, avoiding issues such as inconsistent efficacy and color differences in shampoos and coatings. It is suitable for diverse formulation systems including rinse-off cosmetics, polymer materials, and water-based coatings.

Contact us allen@faithfulbio.com or Whats App：+86 13137770562

Why choose us

• As your upstream partner, our first commitment is quality. Our Pyrithione Zinc Powder is produced under strict production conditions, and key indicators such as content and related substances (individual impurities<0.1%) meet the requirements of the International Pharmacopoeia.
• Secondly, with stable supply and deep cooperation with core production enterprises, Edoxaban powder has a year-round inventory of spot goods, which can be shipped out as soon as possible after placing an order, without the need for long waiting times.

Quality Control

R&D Results

Packaging and Transportation

After-Sales Service

Qualification Certification

Exhibition

FAQ

Q1: What is the difference in dandruff-reducing efficacy between Pyrithione Zinc and ketoconazole?

A1: Both are effective dandruff-reducing ingredients. A randomized trial showed that ketoconazole 2% shampoo improved overall dandruff severity scores better than pyrithione zinc shampoo 1%. However, Pyrithione Zinc has the advantage of continued symptom improvement after discontinuation, making it suitable for long-term maintenance treatment.

Q2: What is the recommended dosage of Pyrithione Zinc in formulations?

A2: The recommended dosage in cosmetics is no more than 1.5%. The commonly used concentration in OTC dandruff-reducing products is 1%-2%. When used as a paint/plastic bactericide, the dosage should be adjusted according to the specific application.

Q3: Will Pyrithione Zinc easily settle or be difficult to disperse when added to a shampoo and conditioner system?

A3: The powder particle size is controllable, and it exhibits excellent dispersion. Combined with conventional emulsification and suspension systems, it can be stably suspended, reducing manufacturing and processing difficulties.

Contact US

We keep high purity Pyrithione Zinc Powder in stock. Contact us allen@faithfulbio.com or Whats App：+86 13137770562 any time .