Raw Dexmedetomidine HCl Powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Raw Dexmedetomidine HCl Powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd has a good credit and reputation in the industry, and have been established for 8 years, always adhering to the core values of "integrity, cooperation, innovation, and responsibility". We constantly innovate and break through in the field of active pharmaceutical ingredients. Our raw Dexmedetomidine HCL powder is our flagship product, and we have full confidence in its quality. Through the active efforts of all our employees, numerous commercial companies have become our long-term and stable partners.

Raw Dexmedetomidine HCl Powder Introduction

Raw Dexmedetomidine HCl Powder is a highly selective adrenergic receptor agonist. Dexmedetomidine hydrochloride is the only sedative that can be awakened during surgery, with certain anti anxiety, analgesic, and diuretic effects. It has the advantages of low respiratory depression, low delirium incidence, and protection of organs such as the heart/kidney/brain. It is mainly used for sedation during tracheal intubation and mechanical ventilation in surgical patients undergoing general anesthesia, as well as for sedation in patients starting intubation and using ventilators during critical care and treatment.Our Dexmedetomidine HCl has a product qualification rate of 99.99% for three consecutive years, with zero quality complaints. Please feel free to choose.

Specifications

Why Choose Us?

production capacity: equipped with imported production equipment to ensure precise and controllable product quality.
small-scale trial production services: Low dose trial orders, reducing trial and error costs, and meeting flexible needs in the early stages of research and development.
Transparent pricing strategy: Develop tiered discount policies based on order volume to optimize long-term cooperation costs.
Safe and reliable logistics guarantee: Strictly control transportation conditions and reduce the impact of transportation risks on products.

Main applications

1. Application in neurosurgery:
Dexmedetomidine hydrochloride plays an important role in neurosurgery by providing stable cerebral hemodynamics, suppressing elevated intracranial pressure during tracheal intubation, maintaining patient comfort during sedation, and easily awakening during neurocognitive and motor function tests. Dexmedetomidine HCl does not increase the incidence of hypotension and bradycardia in neurosurgery.
2. Application in cardiac surgery:
Stress response is an important factor in perioperative cardiovascular complications. Dexmedetomidine HCl can effectively reduce perioperative cardiovascular complications such as myocardial infarction in cardiac surgery patients by controlling stress response and its protective effect on the myocardium, maintaining the balance of myocardial oxygen supply and demand, anti arrhythmic effects.
3. Postoperative adjuvant medication and analgesia:
Dexmedetomidine hydrochloride has a certain preventive effect on postoperative shivering, irritability, nausea and vomiting in patients, thereby reducing the need for postoperative oxygen metabolism, which is particularly important for heart disease patients. For patients with insufficient analgesia, continuous postoperative infusion can improve the efficacy of patient-controlled analgesia (PCA) in patients, while reducing the dosage and dose related toxic side effects.
4. Application in pediatric surgery:
Dexmedetomidine hydrochloride has been used as a preoperative medication for children, providing better compliance and separation from parents. It can reduce the incidence of ventricular and supraventricular tachycardia in children with congenital heart disease after surgery. Postoperative patients are quieter and easier to wake up.

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FAQ

Q1:What is pharmacokinetics of Dexmedetomidine HCl?

A1:It has a first level elimination effect and low oral bioavailability, but its bioavailability through sublingual route can reach 84%. Its steady-state distribution volume (VSS) is 118L, and the final elimination half-life is 2h. The distribution half-life of the rapid distribution phase only takes about 6min, and it has a high protein binding rate (94%).

Q2:What are the side effects of Dexmedetomidine HCl?

A2: The main side effects include hypotension, bradycardia, dry mouth, nausea, pulmonary edema, atelectasis, etc. Long term injection can cause upregulation of receptors, leading to mental tension, agitation, headache, and hypertensive crisis. Not recommended for patients with heart conduction block and ventricular dysfunction

Q3:Does it have any other potential uses?

A3: In addition to its broad application prospects in sedation and analgesia, it can also exert organ protection by inhibiting the release of oxygen free radicals and different inflammatory response factors, as well as suppressing the expression of apoptotic proteins.

Contact Us

 if you need high quality Raw Dexmedetomidine HCl Powder   for research or production，pls contact us at any time: Email: sales12@faithfulbio.com

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