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Riociguat raw powder

Product Name: Riociguat raw powder
CAS NO.:625115-55-1
Molecular formula:C20H19FN8O2
EINECS:641-755-1
Synonyms:Riocguat;BZY 632521
Shelf life: 24 months
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 1g;10g;100g
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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  • Product Description

Xi'an Faithful BioTech Co., Ltd: Your Trusted Riociguat raw powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is located in the northwest city of Xi'an, known as the ancient capital of thirteen dynasties. We supply high-quality Riociguat raw powder. We have strong technical reserves and a rich product pipeline, which can respond to market demand in a timely manner and meet customer concerns. We uphold the core values of "integrity, professionalism, responsibility, and win-win", adhere to the corporate mission of "providing high-quality products and services, continuously meeting customer concerns and market demands", and serve customers and friends from all over the world.

Riociguat raw powder Introduction

Riociguat is a soluble guanylate cyclase activator that can significantly improve patients' exercise tolerance, hemodynamic parameters, cardiac function, and prolong the time to clinical deterioration (PATENT study). In addition, it can effectively treat CTEPH. It is an important signaling enzyme that can be activated by nitric oxide (NO) to catalyze the conversion of guanosine triphosphate (GTP) to the second messenger cyclic guanosine monophosphate (cGMP). Soluble guanylate cyclase is currently the only known NO receptor. The appearance is white powder. Our Riociguat raw powder has undergone rigorous testing and meets international standards. High purity and minimal impurities.

Specifications

Item

Specification

Results

Appearance

white yellowish powder

Conforms

Identification

HPLC/NMR

Almost the same

TotaI Impurity

 1.0%

0.45%

s:ngle impurity 0.3%

0.21%

Residual on ignition

 0.5%

0.19%

Assay

99.0% - 102.0%

99.73%

Conclusion: 

Conform with enterprise specification

 Why Choose Us?

High purity: The product purity is ≥ 99.5% (HPLC), with strict impurity control and compliance with international pharmacopoeia standards and ICH guidelines.
Stable and uniform: Advanced synthesis technology and strict quality control system are adopted to ensure consistent quality of each batch of products with small inter batch differences.
Customized service: We can provide products in different specifications (1kg/aluminum foil bag, 5kg/drum, 25kg/drum, etc.) and packaging forms according to customer needs.
Quick response: Regular orders can be shipped within 3-5 days, and urgent orders can be provided with expedited services to ensure the smooth progress of customer production plans.
Environmental protection concept: adopting green chemical synthesis route, reducing harmful substance emissions, and fulfilling corporate social responsibility.

Main applications

Riociguat raw powder is a soluble guanylate cyclase (sGC) stimulant with the following main uses:

  • Clinical treatment application

Chronic thromboembolic pulmonary hypertension (CTEPH): Used to treat postoperative persistent or recurrent CTEPH, or inoperable CTEPH, in adult patients with WHO heart function grades II-III, to improve motor function.
Arterial pulmonary hypertension (PAH): As a monotherapy or in combination with endothelin receptor antagonists and Epoprostenol, it is used to treat adult patients with PAH classified as II-III by WHO cardiac function, improving their exercise ability and quality of life.

  • Other application areas

Research reagents: used for cardiovascular disease research and drug development, especially in the study of sGC signaling pathway.
Pharmaceutical intermediates: used for synthesizing Riociguat formulations to meet the global market demand for PAH and CTEPH treatment.

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FAQ

Q1:How Riociguat works?

A1:The medication stimulates the sGC enzyme in the blood vessels, which leads to increased production of cyclic GMP, a signaling molecule that causes the vessels to relax and widen.

Q2:Is Riociguat a vasodilator?

A2:Riociguat, a potent vasodilator that is the first in a new class of drugs, has been approved by the Food and Drug Administration for treating two types of pulmonary hypertension in adults.

Q3:How to storage Riociguat?

A3:Please keep refrigerated.

Contact Us

We keep Riociguat raw powder  in stock, if you are looking for it , pls feel free to contact us sales12@faithfulbio.com any time.

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