Ritlecitinib powder
CAS NO.: 1792180-81-4
Molecular formula:C15H19N5O
EINECS:210-077-2
Synonyms:Litoxetine
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 100g
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Ritlecitinib powder Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd provides customers with stable supply guarantee of Ritlecitinib powder. We are a professional company engaged in the supply of innovative drugs, improved new drugs, generic drugs, active pharmaceutical ingredients and intermediates, integrating resources, controlling quality, and serving customers in major regions around the world with dedication. Your recognition is our greatest pride.
Ritlecitinib powder Introduction
Ritlecitinib powder (CAS: 1792180-81-4) is a white to off white solid powder that belongs to the highly selective JAK3 and TEC kinase family irreversible inhibitors. As a new generation of covalent kinase inhibitors, it specifically blocks the JAK3 signaling pathway, precisely regulates immune system activity, and demonstrates significant therapeutic potential in the field of autoimmune diseases. Our Ritlecitinib powder undergoes strict screening and control from raw materials to workshop production, with advanced production equipment introduced to produce high-quality products that comply with pharmacopoeia.
Specifications
| Item | Specification | Result |
Appearance | White powder | Complies |
Identification(TLC) | Positive | Complies |
Assay | ≥98.0% | 99.4% |
Conclusion | Complies with In-house standard | |
Application area of Ritlecitinib powder
- The core active ingredient of Ritlecitinib formulation is used to treat severe alopecia areata in adolescents and adults aged 12 and above. It is currently the first and only oral drug targeting this target that covers adolescent patients.
- In the research of immune-mediated diseases such as vitiligo and ulcerative colitis, due to their high selectivity for JAK3/TEC, they have significant advantages over pan JAK inhibitors in reducing off target toxicity.
- It can also be used for preclinical and clinical research on tumor diseases such as skin T-cell lymphoma.
- As a high-purity standard or synthetic intermediate, it is used for basic research on drug metabolism and efficacy evaluation in domestic and foreign pharmaceutical research and development institutions.
Main Advantages
Strong targeting
Ritlecitinib powder is highly selective towards the JAK3 and TEC kinase families, with a much lower risk of off target adverse reactions compared to the first generation.
Rapid onset
Short half-life (about 1.3-2.3 hours), fast clearance in the body, conducive to precise dosage regulation.
Wide coverage
Patients aged 12 and above can use it, and the available population is wider than similar drugs.
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FAQ
Q1:How it works?
A1:By inhibiting Janus kinase, Ritlecitinib can interfere with abnormal activity of the immune system, reduce inflammation in the immune response, and potentially alleviate symptoms caused by autoimmune diseases.
Q2:What is the main difference between Ritlecitinib and pan JAK inhibitors?
A2:Ritlecitinib is a specific JAK3/TEC covalent inhibitor with high selectivity for other subtypes such as JAK1 and JAK2, resulting in lower risk of adverse reactions and greater safety.
Q3:What are the adverse reactions of Ritlecitinib?
A3:Common adverse reactions (incidence ≥ 1%) include headache, diarrhea, acne, rash, urticaria, folliculitis, fever, atopic dermatitis, dizziness, elevated creatine kinase, herpes zoster, decreased red blood cell count, and stomatitis.
Contact US
We have Ritlecitinib powder. Contact us sales1@faithfulbio.com or Whats App:+86 17782784795 .




