S-Adenosyl methionine disulfate tosylate
CAS NO.:97540-22-2
Molecular formula:C22H34N6O16S4
EINECS:249-946-8
SynonymsS-Adenosyl-5-L-Methionine Tosylate
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 1g,10g
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted S-Adenosyl methionine disulfate tosylate Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd is a company specializing in high-purity functional raw material supply chain services, with over 8 years of experience in operating S-Adenosyl methionine disulfate tosylate products. Our products are exported to 12 countries and regions around the world, and we provide stable supply of S-adenosylmethionine p-toluenesulfonic acid sulfate raw materials year-round. We committed to providing 'zero interruption, zero defect' raw material solutions for formulation factories and brand manufacturers. ”
S-Adenosyl methionine disulfate tosylate Introduction
S-Adenosyl methionine disulfate tosylate is a stable and orally active methyl donor. It solves the problem of poor stability of ordinary S-ADENOSYL-L-METHIONINE by combining SAMe, which has therapeutic activity, with p-Toluenesulonic acid and sulfate ions. This complex salt form not only greatly enhances the stability of raw materials during storage and transportation, but also makes it highly bioavailable in the human body, making it the most mainstream form of SAMe used in the fields of dietary supplements and medicine.
Specifications
Items | Specification | Results |
Appearance | Almost white powder ,hygroscopic,soluble in water | Conforms |
Identification | 1)Chemical reacton 2)IR:consistent with the spectrum obtained with reference substance. 3)HPLC:the retention time of a major peak meets the requirements. | 1)Positive reaction 2)Conforms 3)Conforms |
Acid Value | 1.0~2.0 | 1.5 |
Clarity and color of solution | Not more intensely colored than reference solution Y2. | Conforms |
Heavy metals | N.M.T10PPM | Conforms |
Water | N.M.T 2.5% | 2.0% |
S-adenosyl-L-Homocystein | N.M.T 0.5% | 0.06% |
Methithioadenosine | N.M.T 2.0% | 0.41% |
Adenine | N.M.T 0.5% | 0.28% |
Related substance | The sum area of unknown impurities must be not more than 1.5times of reference solution main peak’s(1.5%) | 0.12% |
(S,S)Isomer | N.L.T 60.0% | 77.0% |
Endotoxin | NMT0.3EU/mg | Conforms |
Microbiological | NMT 1000CFU/g | 10 CFU/g |
p-toluenesulfonatic acid | 21.0%~24.0%(basis on dried) | 22.9% |
Sulfates | 23.5%~26.5%(basis on dried) | 24.8% |
Ademetionine | N.L.T 49.5%(basis on dried) | 51.2% |
Total content | N.L.T 96.0% | 98.9% |
Conclusion:Complies with enterprise standard | ||
Application area of S-Adenosyl methionine disulfate tosylate
The application areas mainly focus on the following three terminals:
- Emotional health and adjunctive therapy for depression: As a methyl donor, it participates in the synthesis of neurotransmitters such as 5-hydroxytryptamine and 3-Hydroxytyramine, and is widely used in dietary supplements for antidepressant and anti anxiety purposes.
- Liver protection: promotes the synthesis of Glutathione, has strong detoxification function, and is commonly used for the repair of alcoholic liver injury, drug-induced liver injury, and adjuvant treatment of cirrhosis.
- Bone and joint health: stimulates the synthesis of cartilage matrix (such as proteoglycans), used to alleviate pain, stiffness, and inflammation caused by osteoarthritis, with fewer side effects compared to traditional NSAIDs drugs.
Main Advantages
- Ultra high purity and stability: The content of S-Adenosyl methionine disulfate tosylate can reach over 99%, with extremely low isomer control and minimal impurities, ensuring maximum biological activity.
- Double salt form, high bioavailability: The sulfate form of p-toluenesulfonic acid makes it difficult to degrade in the gastrointestinal tract, and its absorption rate far exceeds that of ordinary non stable forms of SAMe.
- Natural fermentation source: Produced through microbial fermentation process using natural brewing yeast, non chemically synthesized, in line with the market trend of clean labeling and natural sources.
- Multi effect integration: Simultaneously possessing the triple pharmacological effects of antidepressant, hepatoprotective, and anti proliferative (anti-cancer potential), one raw material can solve multiple health pain points.
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Why choose us
- Supply chain resilience and timeliness: We maintain a constant safety stock, and even during peak raw material seasons, we can promise to ship quickly within 3 working days, solving your worries about "supply disruptions".
- Ultimate purity, cost reduction and efficiency enhancement: The purity of the S-Adenosyl methionine disulfate tosylate raw material we provide is stable at over 99%, which means that in your formula, you can achieve the same efficacy with less addition, reducing your overall formula cost.
- Insurance service: We provide insurance service, and if the total price is increased by 20%, we can resend it for free once in case of transportation issues. This helps you transfer transportation risks.
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FAQ
Q1:What is the toxicity data of S-Adenosyl methionine disulfate tosylate?
A1:High security. The acute oral toxicity LD50 of rats is 3320 mg/kg, which is a practically non-toxic substance. The common adverse reactions are only gastrointestinal discomfort or slight temperature changes at high doses.
Q2:What is the difference between it and ordinary butanedisulfonate salts on the market?
A2:The core difference lies in stability and application. P-toluenesulfonic acid sulfate is currently recognized as the most stable form, particularly suitable for making tablets and capsules.
Q3:What is your minimum order quantity (MOQ)?
A3: Support flexible procurement. The minimum order quantity for sample packaging is 100g, and for commercial bulk orders, it is usually 1kg or 25kg cardboard drums, depending on inventory.
Contact US
Stable supply of high-purity S-Adenosyl methionine disulfate tosylate to help you seize the opportunity in the emotional and joint health market.
Email me sales1@faithfulbio.com.




