Vecuronium Bromide API
CAS.NO:50700-72-6
structural formula:C34H57BrN2O4
EINECS.no:256-723-9
Other names:Vecuronium bromide;norcuron;nc-45;orgnc45
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place; 36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Vecuronium Bromide API Manufacturer & Supplier
Vecuronium Bromide API is a white or off white powder chemical. Odorless, bitter in taste, and hygroscopic. The skeletal muscle relaxation material Vecuronium bromide provided by Xi'an Faithful BioTech Co., Ltd company is mainly used in general anesthesia surgery in clinical practice, especially for endotracheal intubation during general anesthesia. It is essentially a medium effect non depolarizing neuromuscular block material that can achieve complete muscle relaxation.
Vecuronium Bromide API Introduction
Vecuronium Bromide API mainly acts on the neuromuscular junction, blocking the conduction between nerve endings and striated muscles by competing with acetylcholine for nicotinic receptors located on the motor endplate of striated muscles. It should be noted that it only prevents nerve impulses from being transmitted to muscles, without causing muscle fiber bundle tremors, which is different from depolarization neuromuscular blockade. Moreover, it does not block the vagus nerve, and this relaxation effect is reversible. When its effective time passes, muscle function will gradually recover.
Specifications
Item | Specifications | Results |
Appearance | White to yellow solid powder | Conforms |
Identification (IR) | Concordant with reference spectrum | Conforms |
Assay | ≥98% | 98.33% |
Heavy Metals | ≤5ppm | 5ppm Conforms |
Loss on Drying | ≤1.0% | 0.25% |
Residue on Ignition | ≤0.3% | 0.08% |
Total Plate Count | ≤1000cfu/g | 10cfu/g |
Total Yeast & Mold | ≤100cfu/g | 10cfu/g |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
| Conclusion | Conform with enterprise specification （USP 41）. |
Why Choose Us?
1、 Excellent quality standards and global compliance assurance
We strictly follow cGMP and ICH Q7 standards for production, and the purity of Vecuronium bromide powder is stable at ≥ 99.5%. Key impurities (such as related substances, residual solvents, etc.) fully comply with the requirements of the Chinese Pharmacopoeia (ChP), the United States Pharmacopoeia (USP), and the European Pharmacopoeia (EP). Each batch of products is equipped with a complete traceable Certificate of Analysis (COA), impurity mass spectrometry research report, and stability data, supporting the registration and declaration needs of the global high-end formulation market.
2、 Leading process technology and customized service capabilities
We adopt an independently optimized green synthesis process and implement internal control production of key intermediates to ensure the safety and controllability of the supply chain. We support flexible supply from gram level R&D samples to ton level commercial orders, and can provide customized services for specific crystal forms, particle size distributions, and sterile levels that meet different reagents.
3、 Professional one-stop technical support system
We have formed a professional team covering synthesis, analysis, formulation, and regulatory declaration, which can provide customers with full process technical support from structural confirmation, methodological validation to DMF/CEP document writing. Relying on large-scale production bases and fully temperature controlled logistics systems, we ensure stable and efficient product supply, and help customers accelerate project implementation and market access.
We are committed to becoming your trusted Vecuronium bromide API strategic partner. Our email is:sales8@faithfulbio.com.
Precautions
Individualized dosage: Based on the patient's age, weight, physical condition, and anesthesia depth, the doctor will adjust the dosage of vecuronium bromide to achieve the best muscle relaxation effect.
Monitoring neuromuscular function: During use, it is necessary to use a neuromuscular monitor to monitor the degree of muscle relaxation, in order to ensure the effectiveness of medication and timely discontinuation.
Interactions with other Pharmaceutiucal Materials: Vecuronium bromide API powder may interact with other Pharmaceutiucal Materials, such as certain antibiotics, antiarrhythmic API powder, etc. When using, doctors need to consider these factors and adjust the medication dosage or choose other medications if necessary.
Special circumstances of patients: Some patients, such as those with liver dysfunction, kidney dysfunction, hyperkalemia, etc., may require special attention to the use of vecuronium bromide.
Quality Control:
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FAQ
Q1: What are its adverse reactions?
it has minimal effects on cardiovascular health, with occasional occurrences of bronchospasm, skin flushing, rash, and allergic reactions. When used by patients with cirrhosis, cholestasis, or severe renal dysfunction, the duration of muscle relaxation and recovery time are prolonged
Q2: What are the pharmacokinetic characteristics?
The pharmacokinetics of Vecuronium bromide API powder follow a two compartment open model, with a plasma absorption half-life of approximately 4 minutes and an elimination half-life of approximately 31 minutes. Mainly metabolized in the liver, 85% is excreted through bile and 15% through the kidneys. In theory, 60% -90% of it binds to plasma proteins after entering the body.
Q3: How to store?
It should be shaded, sealed, and stored in a cool place (not exceeding 20 ℃). Transport at room temperature and avoid contact with prohibited substances such as oxidants.
Contact us
Choosing us means that you have chosen a partner who is trustworthy in terms of quality, reliability, technology, and business cooperation. We promise to use the highest standards of Vecuronium bromide API powder and services to work with you to ensure the safety, effectiveness, and accessibility of the final formulation product, achieving a win-win situation.Our email address is:sales8@faithfulbio.com, Welcome to call.
