6-Diazo-5-oxo-L-nor-Leucine powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted 6-Diazo-5-oxo-L-nor-Leucine powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd. sells high-purity 6-Diazo-5-oxo-L-nor-Leucine powder. 6-Diazo-5-oxo-l-norleucine is a potent amino acid analog with important applications in multiple fields. As research deepens in areas such as cancer treatment and metabolic disorders, 6-Diazo-5-oxo-l-norleucine, due to its ability to inhibit specific enzymes, particularly those involved in amino acid synthesis, holds potential value in therapeutic research for these diseases. Our company produces 99% pure 6-Diazo-5-oxo-l-norleucine, enabling us to conduct such research with high quality.

6-Diazo-5-oxo-L-nor-Leucine powder Introduction

6-Diazo-5-oxo-L-nor-Leucine powder (DON) is a glutamine antagonist. Due to its structural similarity to glutamine, DON can enter its catalytic center and inhibit its activity through covalent binding or alkylation, thus broadly and effectively inhibiting the activity of various enzymes using glutamine as a substrate. Currently, this compound is being studied for the treatment of diseases such as tumors. Furthermore, after metabolic intervention with 6-Diazo-5-oxo-l-norleucine, skin thickening at psoriatic lesions was significantly reduced, as was the infiltration of immune cells. DON effectively inhibited the local inflammatory immune response. Simultaneously, DON alleviated splenomegaly in psoriatic patients and effectively suppressed the inflammatory immune response in psoriatic diseases. By detecting the expression of pro-inflammatory factors at the site of psoriatic skin inflammation, DON also inhibited the expression of these genes, effectively alleviating the symptoms of psoriasis.

Email: sales9@faithfulbio.com

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Why Choose Us?

1. High Product Purity: Our 6-DIAZO-5-OXO-L-NORLEUCINE boasts a purity exceeding 98%. This high purity ensures accurate and reliable experimental results, minimizing interference from impurities and making it suitable for various high-end scientific research experiments and product development projects.

2. Strong Bioactivity: This product is an effective glutamine antagonist that irreversibly inhibits glutamine metabolism, exhibiting excellent anticancer activity. Particularly noteworthy in pancreatic cancer treatment research, it reduces the self-renewal potential and metastatic ability of tumor cells. It also possesses antibacterial and antiviral activity, meeting the needs of clients in multiple fields such as cancer research and microbiology research.

3. Diverse Product Specifications: We offer various packaging sizes, such as 100mg, 500mg, 1g, and 10g, to meet the needs of clients with different experimental scales. Whether for preliminary experimental exploration or large-scale research projects, a suitable product specification can be found.

4. Comprehensive Quality Assurance System: We have a professional experimental center and a rigorous quality control and validation system, providing COA, HPLC, and other quality inspection reports to ensure stable and reliable product quality.

5. Professional Research Services: We have a dedicated team to track progress and provide clients with expert technical support and consulting services. If clients encounter any problems while using the product, our professional team can provide timely solutions.

6. High Synthesis Difficulty, Stable Supply: The synthesis of 6-DIAZO-5-OXO-L-NORLEUCINE requires stringent conditions, including temperatures as low as -100°C, and yields are low. We possess the professional synthesis technology and production capabilities to ensure a stable supply of the product and meet our clients' long-term needs.

Application Areas

• Scientific Research: As an effective tool compound, it is widely used in enzyme inhibition research, neuropharmacology research, and biochemical research, helping researchers explore metabolic pathways, enzyme functions, and the effects of amino acid analogs on protein synthesis.

• Product Development: Due to its unique structure and biological activity, it has potential value in product design and development, especially in the research and development of products targeting metabolic diseases and cancer.

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FAQ

Q1: What is don 6-Diazo-5-oxo-L-nor-Leucine powder?

A1: 6-Diazo-5-oxo-l-norleucine (DON) is a glutamine antagonist with robust anticancer efficacy; however, its therapeutic potential was hampered by its biodistribution and toxicity to normal tissues, specifically gastrointestinal (GI) tissues.

Q2: What are the biological activities of 6-Diazo-5-oxo-L-nor-Leucine powder?

A2: DON has anticancer activity, especially in the treatment of pancreatic cancer, where it can reduce the self-renewal potential and metastatic ability of tumor cells. In addition, it also possesses antibacterial and antiviral activities.

Q3: What are the storage conditions for 6-Diazo-5-oxo-L-nor-Leucine powder?

A3: Generally, DON powder can be stored at -20°C for 3 years; when prepared as a solution, it can be stored at -80°C for 1 year and at -20°C for 1 month. Repeated freeze-thaw cycles should be avoided.

Contact Us

We have 6-Diazo-5-oxo-L-nor-Leucine powder in stock. Please feel free to contact me if you wish to place an order or have any inquiries about 6-Diazo-5-oxo-L-nor-Leucine powder. Please contact my email sales9@faithfulbio.com.

Email: sales9@faithfulbio.com

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