Brexpiprazole API powder
CAS. NO: 913611-97-9
MF.no:C25H27N3O2S
EINECS.no:811-628-7
Other names:Brexpiprazole;OPC-34712;Brexpiprazole impurity a;CS-1678;OPC 34712; OPC34712; OPC-34712
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place; 36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Brexpiprazole API powder Manufacturer & Supplier
Brexpiprazole is the first compound of dopamine D2, 5-HT1A receptor agonists and 5-HT2A receptor antagonists. Especially, compared with Aripiprazole powder, the Brexpiprazole powder developed by Xi'an Faithful BioTech Co., Ltd. has an increased affinity for the 5-HT receptor and a decreased activity for the D2 receptor. The tolerance performance is also better, the incidence of side effects of sedentary inability is lower, and there is a trend of faster and better efficacy in negative symptoms and cognitive function of schizophrenia. Clinically, Brexpiprazole API powder is usually used in research as an adjunctive treatment for depression, and animal studies show quick results.
Brexpiprazole API powder Introduction
Brexpiprazole API powder is an atypical antipsychotic drug, and although its mechanism of action for treating AAD is not yet clear, it is generally believed to be mediated by binding to partial agonist activity of serotonin 5-HT1A and dopamine D2 receptors, as well as antagonist activity of serotonin 5-HT2A receptors. Research has shown that OPC-34712 powder has broad activity in multiple monoamine systems, with reduced partial agonist activity towards dopamine D2 receptors and increased affinity for specific 5-HT receptors (such as 5-HT1A, 5-HT2A, 5-HT7), resulting in better efficacy and tolerability. It can significantly reduce adverse reactions such as sedentary, restless, or insomnia in subjects.
Specifications
Item | Specifications | Results |
Appearance | White or almost white powder | Conform |
Solubility | Soluble in water and acetic acid | Conform |
Acetate Content (HPLC) | ≤15.0% | 1.2% |
Water Content (Karl Fischer) | ≤8.0% | 1.2% |
Peptide Content(HPLC) | ≥98.0% | 99.7% |
Related Substance (HPLC) | Total lmpurities≤2.0% | 0.3% |
| Largest Single Impurity≤1.0% | 0.2% |
Organic Solvent Residue | Acetonitrile≤0.041% | <0.041% |
| Dichloromethane≤0.060% | <0.060% |
| N,N-Dimethylformamide≤0.088% | <0.088% |
| Conclusion： | Conform with enterprise specification （USP 41）. |
Why Choose Us?
When your project focuses on the new-generation antipsychotic API OPC34712 Powder, choosing a reliable and professional API provider is undoubtedly the most crucial link in your success chain. Among numerous suppliers, we hope to become your first choice with the following advantages:
1. Unparalleled purity and consistent quality
As a structurally complex molecule, the synthesis process and purity control of Brexpiprazole are directly related to the efficacy and safety of the final drug. We adopt the world's leading synthetic routes and purification technologies to ensure that each batch of Brexpiprazole API powder meets and exceeds the strict standards of major global pharmacopoeias such as USP, EP, and ChP. What we promise is not only "qualification", but also to provide your preparations with an outstanding and stable quality foundation, minimizing the R&D and production risks brought about by API variations to the greatest extent.
2. Strictly follow the international cGMP standards
Our entire production system, from starting materials to finished products leaving the factory, operates under a strict and complete cGMP (Good Manufacturing Practice) quality management system. We have mature production techniques, detailed verification documents, and a consistent quality control process throughout, ensuring that our OPC34712 API powder can easily handle any audits and reviews by domestic and international regulatory authorities, paving the way for your products to smoothly enter the global market.
3. Strong large-scale production capacity and stable supply chain
We deeply understand the significance of supply chain stability for pharmaceutical projects. With modern production bases and optimized production processes, we possess large-scale and highly efficient commercial production capabilities, capable of meeting your material requirements at all stages from clinical research to commercial market launch. Whether your demand is in kilograms or tons, we can ensure a stable and timely supply, sparing you the worry of stockouts.
4. Profound technical expertise and comprehensive regulatory support
Choose us and what you get is not just products, but an experienced technical partner. Our team is composed of senior chemists, pharmacologists and regulatory experts, who have a profound understanding of the chemical properties, process optimization and registration regulations of Brexpiprazole. We can provide you with a comprehensive technical data package (DMF/CEP), impurity spectrum studies, and customized technical services to accelerate your formulation research and development and registration process.
5. Highly competitive value positioning
Through continuous process optimization and cost control, we offer you highly competitive market prices while ensuring the highest quality standards. We believe that cooperating with us will help you achieve the best product value while controlling costs, thereby gaining a stronger competitive edge in the terminal market.
When you choose our Brexpiprazole API powder, please contact us immediately through the following methods to start our cooperation journey.
Our email address is: sales8@faithfulbio.com
Brexpiprazole and Aripiprazole are very similar, what are the differences between them?
Yes, in terms of scientific research, they are listed as related products, but Brexpiprazole is considered an upgraded version of Aripiprazole powder. The main difference lies in: 1. Receptor affinity: Brexpiprazole has a stronger affinity for serotonin 5-HT1A and 5-HT2A receptors, while a slightly weaker affinity for dopamine D2 receptors. 2. Clinical efficacy: This difference may mean: 3. Less restlessness: The risk of OPC-34712 causing restless sitting (a painful feeling of unease) is relatively low. 4. Different side effects: Overall tolerance may vary slightly. However, when using it, the best choice should be the core and determined based on the specific situation and reaction of the experimental subjects.
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FAQ
Q1: When can I receive the logistics tracking number? Where can I check the order status?
After the goods are shipped, our staff will send you the logistics tracking number as soon as possible via email, online message, or WhatsApp.
You can also track the real-time status of your order through the following global logistics query websites: http://www.17track.net/en
Q2: Will you confirm the product information with us before the goods are shipped?
Please rest assured that before each batch of goods is shipped, we will conduct a final verification of the product information and confirm with you again. All shipments will be clearly labeled to ensure no mishaps.
Q3: What if the package is detained by customs?
This situation is very rare. To prevent such risks, we provide insurance services for all orders for you to choose from. At the same time, based on the concept of establishing long-term cooperative relationships with customers, we always adopt rigorous and reliable solutions in product packaging and transportation to maximize transportation safety and smooth customs clearance.
Contact US
Please feel free to inquire. Our sales and technical team will be happy to provide you with detailed product specifications, the latest quotes, and tailored solutions to your specific needs.
Let's join hands and use the highest quality Brexpiprazole API powder to bring better treatment options to millions of mental health patients worldwide.
