Synonym: (4-BENZYLPIPERAZIN-1-YL)-[2-(3-METHYLBUTYLAMINO)PYRIDIN-3-YL]METHANONE;nsi-189
CAS NO.: 1270138-40-3
EINECS NO.: 1592732-453-0
Molecular Formula: C22H30N4O
Purity & Grade: 99%; Medicine grade
Character: White Powder
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months" data-aw-url="https://www.faithfulbiochem.com/nootropic-ingredients-powder/nsi-189-powder/" title="NSI-189 powder">
Xi'an Faithful BioTech Co., Ltd. sells high purity NSI-189 powder. Our company is equipped with a professional technical service team, providing full-chain services ranging from demand research, formula customization, process optimization to after-sales technical support. Be able to deeply participate in the front-end product development process of customers, customize exclusive peptide raw material solutions based on their specific efficacy and dosage form requirements, and significantly enhance customer stickiness and the depth of cooperation.
NSI-189 powder is usually a white or off-white powder. Its main mechanism of action is to promote the growth of neurons, especially in the hippocampus, which is crucial for learning, memory and emotion regulation. Studies have shown that NSI-189 may have the effects of enhancing cognitive function and memory formation, anti-anxiety and anti-depression, etc. It also has potential applications in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, as well as in addressing age-related cognitive decline and post-traumatic stress disorder. NSI-189 powder is mainly used for scientific research purposes, such as in animal experiments and cell experiments to study its effects on neurogeneration, cognitive function and other aspects.
Test items | Specifications | Results |
Identification | IR and HPLC spectrum shall conform to the standard sample | Conform |
Appearance | Off-white powder | Conform |
Melting Point | 83℃~86℃ | 84.6℃~85.1℃ |
Loss on Drying | Less than 0.5% | 0.29% |
Purity(HPLC) | NLT 99.0% | 99.48% |
Total Impurity | Less than 1.0% | 0.52% |
Residue On Ignition | ≤0.2% | 0.06% |
Heavy metal | ≤20PPM | ≤3PPM |
Conclusion | Conform with enterprise specification |
High purity guarantee: The purity of the NSI-189 powder we provide is ≥98%, meeting strict quality standards. Each batch of products undergoes professional testing, such as analysis through HPLC and other methods, to ensure the purity and quality stability of the products. They can be used with confidence in scientific research and other related fields.
Reliable source and quality: NSI-189 is derived from Nicotinamide and Pyrazine. We have mature production techniques and strict raw material control to ensure product quality from the source. The production process follows standardized operation procedures to ensure the consistency and reliability of the products.
High product safety: Our NSI-189 powder contains no impurities, excipients or flow agents and other harmful substances, ensuring the safety of the product. Meanwhile, Our product is packaged in tamper-proof sealed containers, which can effectively prevent contamination and degradation during transportation and storage.
Excellent customer service: We focus on customer experience and provide high-quality customer service. From order processing to product delivery, we have dedicated personnel to follow up to ensure that customers can receive the products in a timely and accurate manner. If customers encounter any problems during the purchase and use process, we will respond promptly and solve them.
Research on neurodegenerative diseases: It is used in models such as Alzheimer's disease and Parkinson's disease to explore the mechanisms by which it promotes neural generation in the hippocampus and improves pathological damage.
Research on Cognitive and Emotional Disorders: In animal models of age-related cognitive decline, depression, anxiety, PTSD, etc., the impact on learning and memory as well as emotional regulation is studied.
Research on nerve injury repair: In models of cerebral ischemia and traumatic brain injury, to evaluate its potential role in nerve repair and functional recovery.
Drug development tools: As positive controls, they assist in the screening and mechanism validation of novel neuroactive drugs.
A1: We recently reported that NSI-189 prevented and reversed memory impairments, restored hippocampal neurogenesis, and enhanced expression of synaptic markers in the CNS of type 1 or type 2 diabetic mice while concurrently ameliorating peripheral neuropathy.
A2: ELISA demonstrated that VEGF, GDNF, BDNF, and SCF levels were upregulated in the CM of NSI‐treated hippocampal cells compared to standard growth media (p's < 0.05), with BDNF and SCF much more robustly increased than VEGF and GDNF (p's < 0.05).
A3: The most common adverse events associated with NSI-189 use included headache, dizziness, and somnolence.
We've tailored our NSI-189 powder-related services to fit your exact requirements, providing high-purity products meeting top-tier criteria, customizable packaging solutions, and streamlined logistics to ensure timely arrival. If you need the newest quotations, quality verification documents, or other assistance, contact us without hesitation—we’ll attend to your purchasing needs promptly and thoroughly.
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