Raw NSI-189 phosphate powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Raw NSI-189 phosphate powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd  was founded in 2014 and is a reliable supplier of Raw NSI-189 phosphate powder in the northwest region. Our headquarters is located in the ancient capital of Xi'an. we has a professional, knowledgeable, and young team of high-quality employees, and has established long-term cooperative relationships with multiple universities and institutes in Xi'an. We have strong technical and talent advantages in product development and process research. 

Raw NSI-189 phosphate powder Introduction

Raw NSI-189 phosphate powder is the phosphate form of NSI-189 (HY-13999). NSI-189phosphate can stimulate neurogenesis of neural stem cells. NSI-189 phosphate showed neuroprotective effect in Streptozotocin (HY-13753) induced diabetes mouse model, improved neurological function and cognitive ability after stroke in middle cerebral artery occlusion (MCAo) model of rats, and showed antidepressant activity. It is a white to off white powder. The NSI-189 we provide has a purity of over 98%, low impurities, and strong experimental performance, making it the best choice for your scientific research experiments or product production.

Specifications

Why Choose Us?

From technical consultation to after-sales maintenance, equipped with dedicated service consultants to provide full process support, establish customer files to achieve precise. matching of needs, with an average response time of less than 30 seconds for the customer service team, a quotation accuracy rate of 99%, and an annual customer renewal rate of 92%.
Covering 150+cities across 6 continents, using dedicated air routes in some areas for fast and accurate delivery.
Provide sample procurement and bulk price discount policies to reduce customers' trial and error costs.

Main applications

• Depression treatment

NSI-189 phosphate is a second-generation neuronal monoamine type I (NDI) inhibitor that promotes neuroplasticity by regulating levels of brain-derived neurotrophic factor (BDNF). It is mainly used to treat depression, especially refractory depression (TRD). Multiple Phase II clinical trials have been completed, showing effectiveness for some patients.

• Post traumatic stress disorder (PTSD)

In preclinical studies, the drug has shown potential to improve PTSD related symptoms such as anxiety and memory flashback, and some phase II trials have explored its efficacy in PTSD.

• Adjuvant therapy for Alzheimer's disease

Animal experiments have shown that NSI-189 may assist in improving cognitive function in Alzheimer's disease by enhancing neuronal survival and synaptic plasticity, but it has not yet entered the human trial stage.

• Neuroprotective effect

In vitro studies have shown that it can reduce neuronal apoptosis and may have potential protective effects on neurodegenerative diseases such as stroke and brain injury, but further verification is needed.

• Research tool

As a representative compound of NDI inhibitors, NSI-189 phosphate is used in neuroscience research to help explore the relationship between the BDNF signaling pathway and psychiatric disorders.

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FAQ

Q1: Is NSI-189 phosphate safe to use?

A1: Study concluded that NSI-189 is effective as a safe adjunctive therapy, with the most significant antidepressant and pro-cognitive benefits noted in patients with moderate depression.

Q2:Does NSI-189 phosphate affect memory?

A2: NSI-189 prevented and reversed memory impairments, restored hippocampal neurogenesis, and enhanced expression of synaptic markers in the CNS of type 1 or type 2 diabetic mice while concurrently ameliorating peripheral neuropathy.

Q3:What are the side effects of NSI-189 phosphate​​​​​​​?

A3: The most common adverse events associated with NSI-189 use included headache, dizziness, and somnolence.

Contact Us

Raw NSI-189 phosphate powder​​​​​​​ is not only used to treat severe depression, but its efficacy in other diseases such as Alzheimer's disease, Angelman syndrome, brain injury, etc. is still under development. If you are interested in this or if this is your research area, please feel free to contact us for more product information Email: sales12@faithfulbio.com .