Dermorphin peptide powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Dermorphin peptide powder Manufacturer & Supplier

Dermorphin peptide powder is a natural heptapeptide isolated from amphibian skin. It is a natural heptapeptide μ-opioid receptor (MOR) agonist, which has a powerful inhibitory effect on neuralgia. The unique structure of DERMORPHIN ACETATE is that it does not contain the N-terminal sequence that makes people mentally dependent, and it is sensitive to naloxone. DERMORPHIN ACETATE produced by Xi'an Faithful BioTech Co., Ltd. is strictly implemented according to national standards, and is mainly used in the surgical rehabilitation of animals in clinic. In addition, our products can often be seen in root canal treatment in hospitals and pain relief on racetracks.

Dermorphin peptide powder Introduction

The amino acid sequence of dermorphin is Tyr-d-Ala-Phe-Gly-Tyr-Pro-Ser-NH2. It inhibits neuropathic pain by activating the μ receptor and exhibits significant blood-brain barrier permeability. In vitro studies have shown an IC50 of 0.72 nM for μ receptors expressed in CHO cells. Further studies have found that the N-terminal tetrapeptide of Dermorphin trifluoroacetate salt is the smallest fragment that maintains activity, but the complete heptapeptide exhibits superior analgesic efficacy. Xi'an Faithful BioTech Co., Ltd. has determined the three-dimensional structure of dermorphin and the δ opioid receptor using cryo-electron microscopy, revealing that its YGGF motif binds to the receptor through an orthosteric pocket, with binding specificity determined by differences in the extracellular end of the receptor. Natural Dermorphin HAc peptide powder was discovered in 1989 from the skin of a South American tree frog.

Specifications

Why Choose Us? 

1: Price competitiveness and cost-effectiveness: We can provide high-quality products at prices lower than the market average through efficient supply chain management and location advantages, truly saving costs for our customers. For example, our company has long-term cooperation agreements with major pharmaceutical laboratories and chemical plants in China. We can not only provide our products at good prices, but also offer you reagents and bulk commercial grade raw materials at discounted prices.

2: Product innovation and quality assurance: Emphasis is placed on material selection and process optimization to ensure durability and user experience. Our product optimization is based on customer feedback and adaptation to new national standards. For new technologies and processes, we first use them on a small scale and then promote them on a large scale to ensure that customers can obtain products of different grades and processes.

3: The overall value of the solution: not only selling individual products, but also providing integrated solutions with better prices (such as puzzle series, enzyme reagent series, etc.), helping customers reduce operating costs and save transaction time.

4: Accuracy of demand matching and service support: The product matrix covers all aspects of production and life, with a repurchase rate far exceeding the industry average, ensuring long-lasting practicality; We also provide 24/7 customer service, rapid response mechanism, and long-term after-sales support.

5: Emotion and personalized value: Integrating environmental protection concepts and brand stories into products to establish emotional connections; Support customized services to enhance users' sense of belonging.

These advantages stem from the company's strong R&D team and resource integration capabilities, ensuring that products stand out in the market and create sustained value for users.If you are interested, please contact me via Email: sales8@faithfulbio.com.

Research progress and product preservation of Dermorphin

As mentioned earlier, DERMORPHIN ACETATE is a potent endogenous opioid receptor agonist. It exerts its effects primarily by specifically binding to the μ-opioid receptor (MOR). Experimental studies have shown that upon binding to the MOR, it activates downstream G protein-coupled signaling pathways, inhibiting adenylate cyclase activity and reducing intracellular cAMP production, thereby modulating ion channel activity. For example, inhibiting calcium influx and promoting potassium efflux leads to neuronal hyperpolarization, reducing neurotransmitter release, and ultimately producing a range of effects, including analgesia, respiratory depression, and euphoria. Current research on dermorphin focuses on its potential as a novel analgesic and its mechanism of action in neuroscience. Because Dermorphin peptide powder has high affinity and selectivity for the μ-opioid receptor, it holds promise for the development of analgesics that are more effective and less nociceptive than traditional analgesics. In the field of neuroscience, studying the modulatory effects of dermorphin powder on neuronal activity and neurotransmitter release will provide a deeper understanding of physiological processes such as pain perception and mood regulation. Furthermore, structural modification of Dermorphin trifluoroacetate salt to synthesize analogs with improved pharmacokinetic properties is also a current research hotspot.
Due to the large number of research needs, dermorphin powder requires extreme care in storage, keeping it dry and protected from light. It can be stored at 0-4°C for short-term storage, while -20°C is recommended for long-term storage. Furthermore, due to its high water solubility (and its high solubility in polar solvents such as methanol and ethanol), it is typically stored in solvent in laboratories.

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FAQ 

Q1: What do you do? What products do you have?
xi'an faithful supplies Nootropic ingredients powder, bodybuilding supplements pharmaceutical intermediates (Such as Men's health ingredients, Cosmetic ingredients, Hair care Ingredients, Weight loss ingredients, Anti-cancer ingredients, Painkiller ingredients, etc.), Raw materials for animal and plant growth (Such as Veterinary medicine ingredients, Anthelmintics, Synthetic anti-infective materials, Plant growth agent, Herbicide & Fungicide, Insecticide, etc.), Health supplements ( Such as Food additives, Vitamins, Amino acid, Enzyme,ect.), Plant extracts

Q2.：How to contact with you?
When you meet a product you like, you can directly ask about the product you are interested in through the platform, or leave me a message through email. Our email is sales8@faithfulbio.com

Q3.: How is the quality? I want to test.
Before production and extraction, we will test all raw materials.Quality is our top priority.All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.

Contact Us 

Ready to elevate your nootropic products with our premium Dermorphin peptide powder ? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.

Email: sales8@faithfulbio.com

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