DNSP-11 Peptide

Xi'an Faithful BioTech Co., Ltd: Your Trusted DNSP-11 Peptide Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a technology-based enterprise specializing in the supply of high-purity bioactive peptide raw materials. As a professional intermediary for DNSP-11 Peptide powder, we are not only a provider of products, but also a bridge connecting cutting-edge scientific research needs with high-quality raw materials. Through stable and efficient services, we help customers accelerate their research and development process.

DNSP-11 Peptide Introduction

DNSP-11 Peptide is an 11 amino acid synthetic peptide derived from the precursor protein of glial cell line derived neurotrophic factor (GDNF), appearing as a white to off white powder. Research has shown that DNSP-11 can support the survival of midbrain neurons in vitro, and can be rapidly taken up by neurons in vivo, leading to long-term elevation of dopamine and its metabolites levels, exhibiting GDNF like neurotrophic and protective activity.

Specifications 

Application area

• Neuroscience research

It is a tool molecule for studying the function of the GDNF family and the dopaminergic neuron signaling pathway, used to explore neuroprotective mechanisms.

• Parkinson's disease (PD) drug development

DNSP-11 Peptide has significant activity in dopamine neuron protection and functional recovery, and is widely used for in vitro screening of PD therapeutic drugs and evaluation of efficacy in animal models.

• Cell Biology Experiment

Used to establish neurotoxic cell models such as 6-OHDA induced injury models, and evaluate the anti apoptotic and mitochondrial protective effects of compounds.

Main Advantages of DNSP-11 Peptide

• High purity: Product purity ≥ 98% (HPLC)
• Class GDNF bioactivity: As a functional small molecule analogue of GDNF, it can provide similar neurotrophic support while avoiding the in vivo distribution limitations caused by the high molecular weight of natural GDNF.
• Stability: Physically stable, suitable for various storage environments, and does not bind to heparin, which is beneficial for diffusion and bioavailability in vivo.
• The neuroprotective mechanism is clear: research has confirmed that it exerts anti apoptotic effects through various pathways such as activating the ERK signaling pathway and inhibiting Caspase-3/7 activity,
• Easy to use: Good water solubility (>2 mg/mL), convenient for experimental operation and formulation preparation.

Contact us sales1@faithfulbio.com or Whats App：+86 17782784795

Why choose us

Choosing us as your supplier for DNSP-11 Peptide powder means you have chosen a professional and reliable partner. All of our products strictly follow international standards to ensure purity ≥ 98%, and complete analysis reports are provided for each batch. Whether you need small sample sizes in milligrams or plan to conduct large-scale animal experiments, we can respond quickly with our flexible supply capabilities.

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FAQ

Q1:What is the relationship between DNSP-11 and GDNF (glial cell line derived neurotrophic factor)?

A1:DNSP-11 is an 11 amino acid peptide derived from the precursor protein sequence of GDNF, which has shown similar neurotrophic and protective activity to mature GDNF proteins in multiple studies, but with a smaller molecular weight and theoretically easier distribution in vivo.

Q2:What is the solubility of DNSP-11 and what solvent is recommended for use?

A2:The solubility of H ₂ O in water is greater than 2 mg/mL, so sterile deionized water or PBS buffer can usually be used for dissolution preparation.

Q3:How to store the package after receiving it?

A3:It is recommended to store it in an ultra-low temperature environment of -20 ℃ to maintain its optimal stability. Short term use can be stored in a sealed and dark place at 2-8 ℃.

Contact US

We have DNSP-11 Peptide in stock. Contact us sales1@faithfulbio.com or Whats App：+86 17782784795 at any time .