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H-PRO-LEU-GLY-NH2

Product words: H-PRO-LEU-GLY-NH2
CAS NO.: 2002-44-0
structural formula:C13H24N4O3
EINECS.no:217-902-7
English alias:MSH Release Inhibiting Factor,amide;MIF-1;MELANOSTATIN;H-PRO-LEU-GLY-NH2;MSH-RELEASE INHIBITING FACTOR
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
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  • Product Description

Xi'an Faithful BioTech Co., Ltd: Your Trusted H-PRO-LEU-GLY-NH2 Manufacturer & Supplier

H-PRO-LEU-GLY-NH2 has multiple effects, both blocking the activation of opioid receptors and acting as a positive allosteric regulator of D2 and D4 dopamine receptor subtypes. It also inhibits the release of other neuropeptides such as α - MSH, enhancing melatonin activity. MIF-1 produced by Xi'an Faithful BioTech Co., Ltd. is an endogenous peptide fragment derived from the cleavage fragment of oxytocin. Due to different segmentation and ligation processes, our product usually has different effects in vivo.

H-PRO-LEU-GLY-NH2 Introduction

When MIF-1 produced by our company and experimental monkeys are given, some factors in the body will produce active small molecules that can effectively pass through the blood-brain barrier in a complex combination with it. Researchers are usually called MIF-1 molecules, which have abnormal resistance to metabolism in the blood, and will make experimental monkeys very active and significantly improve their imitation ability. However, the MIF-1 raw material provided by us has obvious effect of inhibiting melanin production when combined with some implants, so the cosmetic grade raw material H-PRO-LEU-GLY-NH2 provided by Xi'an Faithful BioTech Co., Ltd. has potential application prospects in cosmetic medicine and cosmetic industry, and can help many customers in their efforts to reduce skin pigmentation.

Specifications

Item

Specifications

Results

Appearance

White powder

White powder

Solubility

Soluble in water or acetic acid at a to give a clear, colorless solution

Conforms

Identification(MS)

301.3±1.0

299.8

Amino Acid Composition

10% of theoretical

Conforms

Peptide Purity (By HPLC)

≥98.0% by area integration

99.06%

Related Substance(By HPLC)

Total Impurities(%)≤2.0%

0.94%

 

Largest Single Impurity(%)≤1.0%

0.58%

Acetate Content (By HPLC)

≤15.0%

12.4%

Water Content(Karl Fischer)

≤8.0%

4.8%

Bacterial Endotoxins

≤5EU/mg

Conform

Peptide Content (N determination)

≥80.0%

81.25%

Assay

95.0~105.0%

98.45%

Conclusion:

Conform with enterprise specification (USP 41).

 

Why Choose Us? 

1: Price competitiveness and cost-effectiveness: We can provide high-quality products at prices lower than the market average through efficient supply chain management and location advantages, truly saving costs for our customers. For example, our company has long-term cooperation agreements with major pharmaceutical laboratories and chemical plants in China. We can not only provide our products at good prices, but also offer you reagents and bulk commercial grade raw materials at discounted prices.

2: Product innovation and quality assurance: Emphasis is placed on material selection and process optimization to ensure durability and user experience. Our product optimization is based on customer feedback and adaptation to new national standards. For new technologies and processes, we first use them on a small scale and then promote them on a large scale to ensure that customers can obtain products of different grades and processes.

3: The overall value of the solution: not only selling individual products, but also providing integrated solutions with better prices (such as puzzle series, enzyme reagent series, etc.), helping customers reduce operating costs and save transaction time.

4: Accuracy of demand matching and service support: The product matrix covers all aspects of production and life, with a repurchase rate far exceeding the industry average, ensuring long-lasting practicality; We also provide 24/7 customer service, rapid response mechanism, and long-term after-sales support.

5: Emotion and personalized value: Integrating environmental protection concepts and brand stories into products to establish emotional connections; Support customized services to enhance users' sense of belonging.

These advantages stem from the company's strong R&D team and resource integration capabilities, ensuring that products stand out in the market and create sustained value for users.If you are interested, please contact me via Email: sales8@faithfulbio.com.

Mechanism action

The MIF-1 raw material we provide has diverse mechanistic effects in substances that slow down or stop melanin production, including:
1: Inhibition of key enzyme activity:
Inhibit the activity of key enzymes required for melanin synthesis, such as tyrosinase, thereby reducing melanin production. 
2: Regulating transcription factors:
The transcription factors that affect the regulation of genes related to melanin production, such as affecting the expression of MITF by interfering with the activation of CREB, thereby reducing the expression of tyrosinase. 
3: Affects signal pathways:
By affecting intracellular signaling pathways, such as reducing cAMP levels, blocking signal transduction related to melanin production. 
4: Regulating protein expression:
Reduce the protein expression levels of melanin synthesis related proteins (such as TYR, TRP-1, TRP-2). 5: Representative inhibitory factors
6: Luoshen Leaf Extract (HLE):
Inhibiting melanin production by reducing tyrosinase activity, affecting MITF expression, and decreasing protein expression levels of related proteins. 
7: Caffeic acid phenethyl ester (CAPEE):
It can inhibit the binding of MITF to M-box, thereby reducing the expression of related proteins, but it does not affect MITF itself. 
8: Bone morphogenetic cells (BMP):
BMP4 has been found to inhibit the production of melanin. 
9: Multi acid:
Some Keggin type polyacids exhibit a reducing effect on melanin content at the cellular level, although their specific inhibitory mechanism remains to be further studied. 

Quality Control:

H-PRO-LEU-GLY-NH2

R&D Results: 

H-PRO-LEU-GLY-NH2

Packaging and Transportation:

H-PRO-LEU-GLY-NH2

H-PRO-LEU-GLY-NH2

After-Sales Service: 

H-PRO-LEU-GLY-NH2

Qualification Certification:

H-PRO-LEU-GLY-NH2

Transaction Feedback: 

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Exhibition: 

H-PRO-LEU-GLY-NH2

​​​​​​​FAQ 

Q1. : Have you received my payment? How long will it take?
Generally, we can receive your payment the next day, and we will inform you as soon as we receive your payment.
After confirmation payment, we will send out package

Q2.:When will you sent out the goods after successful payment?
A: Normally the order will be delivery within 1-3 days after the order confirmed, except the customized products. 

Q3.:What modes of transportation do you have to choose?
We cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.
And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.

Contact Us 

Ready to elevate your peptide products with our premium  H-PRO-LEU-GLY-NH2 powder ? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.

Email: sales8@faithfulbio.com

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