H-PRO-LEU-GLY-NH2

Xi'an Faithful BioTech Co., Ltd: Your Trusted H-PRO-LEU-GLY-NH2 Manufacturer & Supplier

H-PRO-LEU-GLY-NH2 has multiple effects, both blocking the activation of opioid receptors and acting as a positive allosteric regulator of D2 and D4 dopamine receptor subtypes. It also inhibits the release of other neuropeptides such as α - MSH, enhancing melatonin activity. MIF-1 produced by Xi'an Faithful BioTech Co., Ltd. is an endogenous peptide fragment derived from the cleavage fragment of oxytocin. Due to different segmentation and ligation processes, our product usually has different effects in vivo.

H-PRO-LEU-GLY-NH2 Introduction

When MIF-1 produced by our company and experimental monkeys are given, some factors in the body will produce active small molecules that can effectively pass through the blood-brain barrier in a complex combination with it. Researchers are usually called MIF-1 molecules, which have abnormal resistance to metabolism in the blood, and will make experimental monkeys very active and significantly improve their imitation ability. However, the MIF-1 raw material provided by us has obvious effect of inhibiting melanin production when combined with some implants, so the cosmetic grade raw material H-PRO-LEU-GLY-NH2 provided by Xi'an Faithful BioTech Co., Ltd. has potential application prospects in cosmetic medicine and cosmetic industry, and can help many customers in their efforts to reduce skin pigmentation.

Specifications

Why Choose Us? 

1. Technical advantages: synthesis accuracy and purity guarantee
100% sequence accuracy: Solid phase synthesis (SPPS) and high performance liquid chromatography (HPLC) purification are used to ensure the complete correctness of the amino acid sequence (Pro Leu Gly NH ₂), eliminating missing peptides and misplaced peptides.
Ultra high purity (>98%): The strict purification process greatly reduces impurity content, ensuring reliable and reproducible experimental results, and avoiding erroneous conclusions caused by impurity interference.
• Chiral control: High optical purity L-type amino acids are used throughout the process to prevent contamination by D-type isomers and ensure their biological activity and pharmacological specificity.
2. Quality System: International Standards and Data Transparency
CGMP/ISO dual system quality control: The production environment and processes follow international standards to ensure traceability and auditability throughout the entire process from raw materials to finished products.
• Comprehensive Inspection Report (COA): Provide a detailed COA issued by a third-party authoritative organization, including:
HPLC purity chromatogram
Mass spectrometry (MS) molecular weight confirmation data
• Amino acid composition analysis
Key indicators such as moisture, residual solvents, and endotoxins (<1 EU/mg).
• Authentic and transparent data: Customers can query the full original data by batch number, ensuring peace of mind when purchasing and using.
3. Product stability: professional packaging and transportation guarantee
• Active protection scheme: The product is packaged in sterile, vacuum, nitrogen filled, and light shielded glass bottles, combined with cold chain transportation, to maximize the prevention of peptide oxidation, degradation, and hydrolysis, ensuring that the activity of the product you receive is consistent with that at the time of leaving the factory.
4. Supply Chain Strength: Stable Supply and Emergency Response
• Large scale flexible production: With rapid response production capabilities from milligrams to grams, short supply cycles, and uninterrupted supply, we ensure the smooth progress of your scientific research projects.
Strict inventory management: Adopting the first in first out (FIFO) principle and regularly monitoring the stability of inventory to ensure that every gram of product shipped is in the best condition.
5. Service Value: Technology Empowerment and Deep Collaboration
Research support partners: We provide not only products, but also solutions. Attached are professional literature, recommended dissolution solutions (such as using ultrapure water or extremely dilute acetic acid for dissolution), and application notes (commonly used in neurobehavioral and Parkinson's disease research).
Customization capability: It can flexibly provide specific packaging specifications, concentration packaging, and even customized synthesis services for derivatives, truly meeting personalized scientific research needs.If you are interested, please contact me via Email: sales8@faithfulbio.com.

Mechanism action

The MIF-1 raw material we provide has diverse mechanistic effects in substances that slow down or stop melanin production, including:
1: Inhibition of key enzyme activity:
Inhibit the activity of key enzymes required for melanin synthesis, such as tyrosinase, thereby reducing melanin production. 
2: Regulating transcription factors:
The transcription factors that affect the regulation of genes related to melanin production, such as affecting the expression of MITF by interfering with the activation of CREB, thereby reducing the expression of tyrosinase. 
3: Affects signal pathways:
By affecting intracellular signaling pathways, such as reducing cAMP levels, blocking signal transduction related to melanin production. 
4: Regulating protein expression:
Reduce the protein expression levels of melanin synthesis related proteins (such as TYR, TRP-1, TRP-2). 5: Representative inhibitory factors
6: Luoshen Leaf Extract (HLE):
Inhibiting melanin production by reducing tyrosinase activity, affecting MITF expression, and decreasing protein expression levels of related proteins. 
7: Caffeic acid phenethyl ester (CAPEE):
It can inhibit the binding of MITF to M-box, thereby reducing the expression of related proteins, but it does not affect MITF itself. 
8: Bone morphogenetic cells (BMP):
BMP4 has been found to inhibit the production of melanin. 
9: Multi acid:
Some Keggin type polyacids exhibit a reducing effect on melanin content at the cellular level, although their specific inhibitory mechanism remains to be further studied. 

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Contact Us 

Ready to elevate your peptide products with our premium  H-PRO-LEU-GLY-NH2 powder ? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.

Email: sales8@faithfulbio.com

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