CAS NO.: 210302-17-3
structural formula:C16H10F2N6O
EINECS.no:201-118-7
English alias:BAM15;CS-2890;BAM 15
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents." data-aw-url="https://www.faithfulbiochem.com/api-powder/bam15-raw-powder/" title="BAM15 raw powder">
BAM15 raw powder is a novel uncoupling agent for mitochondrial protonophore, which can protect mammals from acute renal ischemia-reperfusion injury and cold induced microtubule damage. BAM 15 is also an effective AMPK activator. BAM 15 can alleviate apoptosis caused by transport in iPS differentiated retinal tissue. Xi'an Faithful BioTech Co., Ltd provides CS-2890 raw powder with a strict quality control system, committed to ensuring high purity and stability of the product, which can meet your research or subsequent development needs.
SStudies have shown that BAM15 is a proton carrier uncoupler for mitochondria, and its off-target effect is less (EC50 = 270 nM in mitochondria of L6 myoblasts). Compared with another decoupling agent FCCP with the same effect, BAM15 can increase the maximum rate of mitochondrial respiration without depolarization of plasma membrane. In addition, BAM15 has been proved to stimulate energy consumption, prevent obesity and enhance blood sugar control in rodent models. In mice, BAM15 raw powder has been proved to reverse obesity and insulin resistance caused by diet. According to the latest research, its weight loss mechanism is to increase energy consumption, promote fat oxidation and reduce lipid accumulation by depolarization of mitochondrial membrane potential without inhibiting ATP synthesis.Another study shows that it can reduce transport-induced apoptosis in iPS-differentiated retinal tissues.
Item | Specifications | Results |
Melting Point | ≥420°C | 422 °C |
Appearance | White to beige powder | Complies |
Identification | In accord CP2010 | Complies |
Related Substances | In accord CP2010 | Complies |
Loss on drying | < 0. 1% | 0.2% |
Residue on | < 0. 1% | 0.04% |
Heavy metals | NMT 10 PPM | Conforms |
Pb | ≤0.5ppm | 0.11ppm |
As | ≤0.5ppm | 0.14opm |
Related substance | Max Single Impurity ≤0.5% | 0.14% |
Total plate count | ≤1,000cfu/g | 3.28 cfu/g |
Mold and Yeast | ≤100cfu/g | 0.12 cfu/g |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
Staphylococcus aureus | Negative | Negative |
Content content | Calculation dry product,C16H10F2N6O 99.0%-101.5% | 99.3% |
Conclusion: | Conform with enterprise specification (USP 41). |
1. Product technology and quality
High purity and high standard: the raw powder of BAM15 has a high purity of > 98% or > 99%, which strictly meets the scientific research level or higher standard.
Excellent stability: the product has excellent chemical stability and batch consistency, ensuring the reliability and repeatability of experimental results.
Rich product line: Besides BAM15, other rare and difficult small molecular compounds or inhibitors may be provided to meet diversified needs.
2. R&D and innovation capabilities
Powerful synthesis process: it has independent and optimized chemical synthesis path, which can stably prepare difficult compounds.
Customized service: Have the ability to customize synthesis and structural modification for customers, and provide flexible research solutions.
Professional application support: the technical team can provide professional technical documents, application notes and some pharmacological and toxicological data to empower customers' research.
3. Production and supply chain
Large-scale production capacity: it can realize stable mass production from gram level to kilogram level, and ensure the supply demand of customers from small trial to pilot test.
Stable supply chain: the core raw materials are produced by ourselves, and the supply chain is self-controllable, avoiding the risk of supply interruption.
Strict quality control system: having ISO certification or following cGMP standard quality management norms, and tracing the whole process from raw materials to finished products.
4. Service and support
Professional technical support team: provide responsive and professional technical consultation and answer customers' questions in research and application.
Regulatory compliance support: provide complete documents such as COA (Quality Inspection Report) and MSDS (Material Safety Data Sheet) to help customers comply.
Flexible business cooperation: provide flexible packaging specifications, competitive prices and convenient logistics solutions.
5. Brand and reputation
Industry word-of-mouth and cases: Have successful cooperation cases with well-known universities, research institutes or pharmaceutical companies, and have a good reputation.
Long-term focus and experience: long-term focus on the research and development of compounds in specific fields such as metabolic diseases and anti-cancer, with deep experience and profound understanding.If you need to purchase BAM15 raw powder, please leave me a message. My email address is: sales8@faithfulbio.com
BAM15 raw powder is a mitochondrial energy decoupling agent. The current research is still mainly in the preclinical stage, and its potential is mainly focused on the treatment of obesity and related metabolic diseases (such as non-alcoholic fatty liver disease, type 2 diabetes). As a raw material manufacturer of this compound, our products have the following advantages:
1. Unique mechanism of action
BAM15 resists weight gain by reducing the efficiency of cellular mitochondria, allowing them to burn more energy, which is different from the traditional weight-loss drug pathway that mainly suppresses appetite or reduces absorption.
2. Multiple metabolic benefits
Research has shown that BAM15 not only reduces weight, but may also help lower blood sugar and insulin levels, improve insulin sensitivity, and reduce fat accumulation in the liver, kidneys, and blood.
3. Widely applicable potential
The research of CS-2890 suggests that it may be used to treat a series of health problems, including obesity, type 2 diabetes, non-alcoholic fatty liver disease and some cancers
4. Higher safety in use
In animal models, it has been shown to reduce weight, improve insulin sensitivity, lower liver fat and blood sugar, and compared to other uncoupling agents (such as DNP), its therapeutic window may be wider and its safety features may be better.
Q1.:How do you treat quality complaint?
First, we will never evade problems and responsibilities, and seek an optimal solution through communication.
Second, If there is a real quality problem caused by us, we will send you free goods for replacement or refund.
Q2:.What is your Return Policy?
Your satisfaction is very important to us. If there are any problems with the product you receive, please contact your account manager within 15 days of receiving of your order. Upon receipt and inspection, Faithful will issue a credit, refund or replacement.
Q3.:Is a signature required for the shipping?
Our shipping method requires no signature from your side upon delivery.
Ready to elevate your API with our premium BAM15 raw powder? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.
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