Candesartan API
Synonym: Candesartan M1;Candesartan Cilexetil EP IMpurity G
CAS NO.: 139481-59-7
EINECS NO.: 604-138-8
Molecular Formula: C24H20N6O3
Purity & Grade: 99%; Medicine grade
Character: White powder
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-10 days
Store & Shelf life: Cool & dry place; 36 months
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Candesartan API Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd. sells high-quality Candesartan API. Our company’s competitive edges are anchored in four core pillars: quality, technology, supply capacity, and compliance. We deliver product purity exceeding 99%, with certain patented processes pushing this benchmark to an impressive 99.94%. Impurity levels are strictly controlled below 0.1%, fully aligning with international pharmacopoeia standards. And complemented by our global logistics network, we ensure prompt and reliable delivery to clients worldwide.
Candesartan API Introduction
Candesartan API is primarily used to treat hypertension. It is rapidly hydrolyzed in the body into its active metabolite, Candesartan. Candesartan is an angiotensin II AT1 receptor antagonist, antagonizing the vasoconstrictive effects of angiotensin II by binding to AT1 receptors in vascular smooth muscle, thereby reducing peripheral vascular resistance. Another theory suggests that Candesartan may exert its antihypertensive effect by inhibiting the secretion of alpha-adrenergic kinase II. Candesartan does not inhibit kininase II and does not affect bradykinin degradation.
COA
| Test items | Specifications | Results |
| Appearance | A white or almost white powder | White powder |
| Identification-IR | Complies with the reference spectrum | Complies |
| Identification-UV | Maximal absorptions at 254nm, minimum absorption at 242nm | Complies |
| Water | ≤0.3% | 0.19% |
| Residual solvents | ||
| Methanol | ≤3000ppm | Not found |
| Ethanol | ≤5000ppm | Not found |
| Ethyl ether | ≤5000ppm | 68ppm |
| Acetone | ≤5000ppm | 482ppm |
| Ethyl acetate | ≤5000ppm | Not found |
| Dichloromethane | ≤600ppm | Not found |
| Dimethylformamide | ≤880ppm | Not found |
| Related substances | ||
| Impurity A | ≤0.15% | <0.05% |
| Impurity B | ≤0.3% | <0.05% |
| Impurity F | ≤0.2% | <0.05% |
| Impurity G | ≤0.2% | <0.05% |
| Impurity H | ≤0.15% | Not found |
| Other individual impurity | ≤0.10% | 0.04% |
| Total impurities | ≤0.6% | 0.21% |
| Sulfated ash | ≤0.1% | 0.06% |
| Heavy metals | ≤10ppm | <10ppm |
| Assay(Dried substance) | 99.0~101.0% | 99.8% |
| Conclusion | Conform with enterprise specification | |
Why Choose Us?
Our Candesartan API undergoes rigorous quality control (QC) measures to ensure a purity of at least 99.0%. Our products fully comply with and exceed international pharmacopoeia standards such as USP (United States Pharmacopeia), EP (European Pharmacopeia), and BP, ensuring the safety and efficacy of your final product.
As a direct manufacturer, we possess strong production capabilities and a stable supply chain, ensuring a continuous and reliable supply of Candesartan API, avoiding uncertainties from intermediaries and guaranteeing uninterrupted production schedules.
Our team has extensive technical experience, ensuring not only efficient production but also comprehensive product support to assist you in solving technical challenges during formulation development and manufacturing.
Application Areas
This is Candesartan's most widespread and primary application. It lowers blood pressure by effectively dilating blood vessels and reducing peripheral resistance by blocking the binding of angiotensin II to AT1 receptors.
Candesartan is widely used to treat congestive heart failure.
Candesartan may also have a protective effect against other types of chronic kidney disease.
Some studies suggest that Candesartan can be an effective product for preventing migraine attacks.
By effectively controlling blood pressure, it directly helps reduce the incidence of stroke in high-risk groups.
Quality Control:
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FAQ
Q1: Can Candesartan API make you tired?
A1: your skin is paler than usual, you feel tired, faint or dizzy, or you get purple spots, any sign of bleeding, sore throat and a high temperature – these can be signs of a blood or bone marrow disorder.
Q2: Is Candesartan API bad for your liver?
A2: Candesartan is associated with a low rate of transient serum aminotransferase elevations and has been linked to rare instances of acute liver injury.
Q3: Do Candesartan API cause weight gain?
A3: Candesartan treatment did not significantly affect weight gain, although there was a trend for weight gain to be less in the obese candesartan rats.
Contact Us
Candesartan API stock available for immediate shipment! All products meet purity standards, are fully compliant, and ship quickly. Contact us as soon as possible to secure your supply and avoid stockouts! Please contact my email sales9@faithfulbio.com.
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