Crotamiton API

Xi'an Faithful BioTech Co., Ltd: Your Trusted Crotamiton API Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a leading supplier of Crotamiton API. We have been established for 8 years and have gathered thousands of API raw materials, committed to providing one-stop purchasing services. Sincere is located in the ancient capital of Xi'an, supplying chemical reagents, pharmaceutical raw materials, and plant extracts. We have established cooperative relationships with multiple domestic pharmaceutical companies and are committed to providing customers with one-stop purchasing services, saving you both physically and mentally.

Crotamiton API Introduction

Crotamiton API, also known as (2E)-N-Ethyl-N-(2-methylphenyl)-2-butenamide, is a drug used to treat scabies, with the molecular formula C13H17NO. The appearance is a colorless to light yellow viscous liquid. It has a local anesthetic effect and can treat various types of pruritus. And it has a specific killing effect on scabies mites, which can act on the nervous system of scabies mites, causing them to paralyze and die. In addition, it also has an inhibitory effect on the growth of streptococcus and staphylococcus. Our products undergo strict quality control to ensure consistent purity and validity of pure products.

Specifications

Why Choose Us?

Ultimate controllable quality, building a solid foundation for formulation safety

• Raw material purity meets the standard: the product purity is ≥ 99.0% (in accordance with pharmacopoeia standards such as the Chinese Pharmacopoeia, USP, EP, etc.), the impurity content is extremely low (individual impurity ≤ 0.1%, total impurity ≤ 0.5%), there is no problem of excessive heavy metals or residual solvents, and the quality risk of the formulation is avoided from the source.
• Stable production process: Adopting mature synthesis technology, closed-loop production is carried out throughout the process, and key processes (such as purification and drying) are controlled by automated equipment. The stability error between batches is ≤± 0.3%, ensuring that your formulation production process is reproducible and of uniform quality.

Stable and reliable supply, ensuring production continuity

• Adequate production capacity: With a large-scale production workshop, we can meet your full stage usage needs from laboratory trials, pilot tests to commercial large-scale production.
• Strong risk resistance capability in the supply chain: Core raw materials are backed up by dual suppliers, production plans are flexibly adjusted, inventory turnover is efficient, urgent orders can be processed urgently.

Main applications

Crotamiton API, as an external anti parasitic and anti itch active pharmaceutical ingredient, has its core applications concentrated in the field of pharmaceutical preparations. It mainly exerts its effects through the production of clinical or household external preparations, including:

• Treating scabies: This is the main use of Crotamiton. It can kill scabies mites (the pathogen that causes scabies) and alleviate the severe itching caused by scabies mite bites. It is a commonly used raw material for clinical treatment of scabies and can be made into cream, ointment and other dosage forms. It is suitable for adults and children (the concentration needs to be adjusted according to age).
• Relieve skin itching: It can be used to treat non infectious skin itching, such as eczema, dermatitis (contact dermatitis, neurodermatitis, etc.), itching caused by skin itching, etc. By inhibiting the itch transmission of skin nerve endings, it reduces patient discomfort. Relevant preparations are widely used in clinical dermatology and home care.
• Auxiliary deworming: It also has a certain inhibitory or killing effect on other skin parasites (such as pubic lice), and can be used as the core material of related deworming topical preparations to assist in the treatment of skin problems caused by parasites.

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FAQ

Q1:What is the mechanism of action of crotamiton?  

A1:Crotamiton relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching. Due to this cooling effect it is also effective for the relief of sunburn.

Q2:Is crotamiton antifungal?

A2:Crotamiton is a topical antifungal and antiparasitic agent. Crotamiton harms the motor system of mites that causing Filariasis, Scabies, Strongyloidiasis and Onchocerciasis, which renders them immobile. It also has antipruritic actions.

Q3:Is crotamiton toxic?

A3:Crotamiton is an anti-infective substance with action against scabies. It is highly volatile. Little data is available regarding its environmental fate or ecotoxicity. It has a moderate mammalian oral toxicity.

Contact Us

We keep good quality Crotamiton API in stock? Are you looking for it? pls contact sales12@faithfulbio.com to get latest quotation.