Ezetimibe API Powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Ezetimibe API Powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a leading supplier of Ezetimibe API Powder. We have been established for 8 years, always adhering to the business philosophy of "quality first, customer first", advocating the corporate philosophy of "people-oriented, pragmatic and innovative", constantly improving our market competitiveness, and striving to make our enterprise an excellent enterprise in the chemical industry. Our products have attracted the attention of customers from over 20 countries around the world with their excellent quality, and have become our loyal customers.

Ezetimibe API Powder Introduction

Ezetimibe API Powder is a white crystalline powder with a melting point of approximately 163 ℃, which is stable at room temperature. It is a novel type of selective cholesterol absorption inhibitor that inhibits cholesterol absorption by binding to the membrane protein (relative molecular weight 145X103) on the small intestinal brush border membrane vesicles, reducing the transport of cholesterol from the intestine to the liver and decreasing its storage; It can enhance the clearance of cholesterol in the blood, thereby reducing plasma cholesterol levels. Our Ezetimibe API Powder is a pharmaceutical grade raw powder that meets international standards and is a high-quality raw material for scientific research and production.

Specifications

 Why Choose Us?

With the cost advantage brought by large-scale production, our raw material prices have strong competitiveness in the industry, without sacrificing quality; Provide flexible procurement solutions (batch procurement, long-term agreement procurement, etc.), and enjoy tiered discounts for large quantities to meet your needs throughout the entire stage from research and development trials, pilot testing to commercial production, reducing your capital occupation costs.

Real time tracking of order progress, providing logistics trajectory queries to ensure timely delivery of goods; If there are any quality objections, we promise to provide a solution in a timely manner. Our Ezetimibe API Powder has been stably supplied to many well-known pharmaceutical companies in China, and the product quality is trustworthy.

Main applications

Ezetimibe is a highly selective cholesterol absorption inhibitor and a key raw material for lipid-lowering drugs. Its core use revolves around the treatment of dyslipidemia related diseases, including:

• Used for synthesizing finished drugs to treat primary hypercholesterolemia (including familial and non familial hypercholesterolemia), by inhibiting intestinal absorption of cholesterol, reducing plasma total cholesterol and low-density lipoprotein cholesterol (bad cholesterol) levels, while mildly increasing high-density lipoprotein cholesterol (good cholesterol) and reducing triglycerides;
• Combined with statins, used for patients who cannot achieve ideal blood lipid control goals solely with statins, to achieve synergistic lipid-lowering effects;
• Used for synthesizing therapeutic drugs for homozygous familial hypercholesterolemia as an adjuvant therapy to help patients further control their blood lipid levels and reduce the risk of cardiovascular disease;
• Suitable for patients with hypercholesterolemia who are intolerant or unable to use statins, providing a safe and effective lipid control plan.

Its unique mechanism of action (does not affect the absorption of fat, fat soluble vitamins, etc.), high safety, and is one of the important raw materials for blood lipid management.

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FAQ

Q1:Which part of the body does ezetimibe act on?

A1:Ezetimibe only acts on the small intestine.

Q2:What is the difference between statins and ezetimibe?

A2:Ezetimibe inhibits cholesterol absorption in the intestine whereas statins inhibit cholesterol production primarily in the liver; so they have complementary effects.

Q3:What is the mechanism of action of ezetimibe?

A3:By reducing enterocyte cholesterol absorption, chylomicron formation and secretion, as well as the back flux of cholesterol from the bile, ezetimibe depletes hepatic pools of cholesterol and increases expression of the LDL receptor on the surface of hepatocytes, resulting in reductions in serum levels of LDL-C.

Contact Us

Our flag product-Ezetimibe API Powder is 99% purity. if you need it for  your research or production, please contact us via sales12@faithfulbio.com.