PGE1 API powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted PGE1 API powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is the main supplier of PGE1 API powder. Since our establishment, we have always adhered to the concept of "integrity management", insisted on "quality first" and "customer first", and gained wide recognition from customers around the world. The products we supply mainly include pharmaceutical raw materials, pharmaceutical intermediates, plant extracts, etc. The product quality is superior and the price is reasonable. Help every customer's career soar.

PGE1 API powder Introduction

PGE1 API powder is a highly efficient bioactive substance secreted by the human body, which has a strong vasodilation effect and can inhibit platelet aggregation. It has extremely strong physiological activity and is an important substance for regulating cell function. It acts on almost all physiological reactions and is widely distributed in the body with low content. Normal tissue cells in the human body can synthesize it, but it quickly becomes inactive after exerting local biological effects. The white to light yellow powder we produce strictly controls every step of the production process to ensure product purity and impurities meet international standards.

Specifications

 Why Choose Us?

High purity and low impurities: using advanced synthesis technology (chemical synthesis+biological purification coupling technology), the product purity is ≥ 99% (HPLC detection), and key impurities (such as prostaglandin isomers and degradation products) are controlled below 0.1%
Efficient synthesis process: "Green catalytic synthesis route", with a yield 15% -20% higher than the industry average, significantly reducing raw material costs and providing customers with more competitive purchasing prices.
Quick response: Equipped with a professional technical service team to respond to customer inquiries within 24 hours.

Main applications

PGE1 API powder is an endogenous Prostaglandin with clear physiological activity, and its active pharmaceutical ingredient is mainly used in the development of pharmaceutical preparations. Its core applications focus on the following clinical fields, and it also has the potential for partially compliant functional applications:

• 1. Core clinical therapeutic applications (mainstream applications)

Erectile dysfunction (ED) treatment: By dilating the corpus cavernosum blood vessels of the penis and improving local blood circulation, it is one of the first-line active pharmaceutical ingredients for treating ED. It can be made into injection, cream, suppository and other dosage forms, suitable for patients with organic or mixed ED, with fast onset and high safety.
Peripheral arterial disease (PAD) treatment: dilates peripheral blood vessels, reduces blood viscosity, inhibits platelet aggregation, improves lower limb and peripheral blood circulation, used to treat thromboangiitis obliterans, intermittent claudication, etc., and relieve symptoms such as limb ischemia, pain, and chills.
Maintenance of patent ductus arteriosus (PDA) in neonates: For premature infants (especially those with extremely low birth weight), PGE1 can maintain the opening of the ductus arteriosus, ensure pulmonary and systemic blood circulation, and buy time for subsequent treatment. It is a key raw material for neonatal intensive care units (NICUs).
Inflammation related adjuvant therapy: It has the effect of inhibiting inflammatory response and protecting mucosal barrier, and can be used as an adjuvant therapy for rheumatoid arthritis and osteoarthritis. It can also be used as a raw material for mucosal protectants for gastric ulcers and duodenal ulcers (with optimized formulation).

• 2. Potential functional/health applications

Improving microcirculation: Based on its vasodilatory effect, it can be used as a functional food or health product ingredient to alleviate microcirculation disorders in the lower limbs of sedentary individuals and peripheral circulation disorders in middle-aged and elderly individuals (such as cold hands and feet).
Anti fatigue and tissue repair: By improving local oxygen supply and nutrient delivery, it assists in relieving post exercise muscle fatigue and promoting tissue repair.

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FAQ

Q1:Where is Prostaglandin E1 metabolized?

A1:Prostaglandin E1 mainly oxidizes the hydroxyl group at position 15 of Prostaglandin E1 to a ketone group through 15 hydroxydeaminase (PGDH), causing it to lose physiological activity, and then undergoes a series of changes to form metabolic end products. 15 hydroxydeaminase (PGDH) is widely present in lung, liver, kidney, and adipose tissue, and it is generally believed that over 80% of Prostaglandin E1 is inactivated in the lungs.

Q2:What is the difference between the targeting of PGE1 API powder and tumor targeted drugs?

A2:PGE1 API powder is passively targeted, while tumor targeting drugs are actively targeted. When inflammatory lesions occur in blood vessels, blood vessels harden, or blood vessels spasm, blood flow changes from normal to abnormal, and PGE1 API powder is easily deposited at the site of vascular lesions, exerting its therapeutic effect.

Q3:Does PGE1 API powder inhibit platelet aggregation and cause bleeding?

A3: PGE1 API powder does not affect the reduction of platelet count or the coagulation mechanism of patients while inhibiting platelet aggregation. It won't cause bleeding.

Contact Us

Our PGE1 API powder, with "high purity, high stability, and high adaptability" as its core competitiveness, not only meets the strict quality requirements of pharmaceutical preparations, but also provides reliable raw material support for the compliant development of functional health products. Welcome to inquire via sales12@faithfulbio.com.