Quinidine 99% powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted Quinidine 99% powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a company that focuses on chemical and pharmaceutical raw materials, intermediates, and plant extracts, and is highly trusted by customers. We supply Quinidine 99% powder. We have a complete, systematic, and scientific quality management system to ensure that each of our products can withstand customer recognition and market testing. For many years, we have always adhered to the corporate philosophy of integrity management, quality first, and customer first, and have established good cooperative relationships with numerous customers.

Quinidine 99% powder Introduction

Quinidine is a natural alkaloid found in the bark and root bark of the cinchona tree, which has long been used to treat malaria. Quinidine also has other important biological activities, such as resistance to heat and arrhythmia. In recent years, the application of Quinidine as a chiral catalyst or ligand in chemical catalysis has received increasing attention. Used in medicine to treat arrhythmia, it can correct the irregularity of heart beating and restore normal rhythm. Our product has undergone multiple layers of strict quality control, and the final product is Quinidine 99% powder.

Specifications

Why Choose Us?

Our production base has independently developed the Quinidine 99% powder synthesis process. After years of technological iteration, we have achieved large-scale and continuous production, which can not only stably control product yield but also effectively reduce unit costs, providing you with more competitive quotes in the market.
We have a regular safety stock to ensure timely delivery of orders, with flexible minimum order quantities and support for both small and large quantities of samples.
We choose multi-channel transportation to help customers receive their goods quickly and safely.

Main applications

Quinidine 99% powder is mainly used for the preparation of clinical antiarrhythmic drug formulations, with core applications focused on the treatment of cardiac electrophysiological abnormalities, as follows:

• Treatment of rapid arrhythmia

Quinidine can block sodium channels on the myocardial cell membrane, reduce myocardial autonomy, slow down conduction velocity, and prolong the effective refractory period. It is commonly used in clinical practice to treat atrial fibrillation, atrial flutter, and maintain sinus rhythm. It can also be used to treat other rapid arrhythmias such as supraventricular tachycardia and premature ventricular contractions.

• Pharmacological research and drug development

As a classic model of antiarrhythmic drugs, Quinidine raw materials have also been used in cardiovascular pharmacological mechanism research, comparative experiments of new antiarrhythmic drugs, as well as basic research on pharmacokinetics, toxicology, and so on.

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FAQ

Q1:Is quinidine a sodium channel blocker?

A1:Quinidine reduces Vmax presumably by blocking cardiac sodium channels. In therapeutic concentrations, quinidine causes a small amount of tonic block. Upon depolarization of the cardiac cell membrane, a use-dependent block develops.

Q2::What is the mechanism of action of quinidine?​​​​​​​

A2:Like all other class I antiarrhythmic agents, quinidine primarily works by blocking the fast inward sodium current (INa). Quinidine's effect on INa is known as a 'use dependent block'. This means at higher heart rates, the block increases, while at lower heart rates, the block decreases.

Q3:Is quinidine an inducer or inhibitor?

A3:Quinidine is an inhibitor of cytochrome P450 (CYP) 2D6 and P‐gp as well as a substrate of CYP3A4 and P-gp.

Contact Us

Quinidine 99% powder is one of our flag products. please feel free to contact us via sales12@faithfulbio.com.