Carbidopa API powder
CAS NO.: 38821-49-7
Molecular formula:C10H16N2O5
Synonyms:Carbidopa,S-(-)-carbidopa;Carbidopa monohydrate
Shelf life: 24 months
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 100g;1kg
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Carbidopa API powder Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd is a leading supplier of Carbidopa API powder in the northwest region of China. We always adhere to the principle of diligence and integrity first, providing customers with high-quality puzzle products. At the same time, our products also cover plant extracts, pharmaceutical intermediates, and peptide raw materials. With our passion, diligence, and continuous pursuit of excellence, we have won the recognition and repurchase of customers worldwide.
Carbidopa API powder Introduction
Carbidopa API powder is most commonly used in combination with levodopa to treat the symptoms of Parkinson's disease. It is a decarboxylase inhibitor that does not cross the blood-brain barrier. By itself, carbidopa has no therapeutic effect for Parkinson's, but it significantly enhances the effects of levodopa. It is a kind of white cryatalline powder.We improve production processes, increase product yields, and produce API powders that meet international standards, making us your top choice for scientific research or production.
Specifications
| Items | Specification | Results |
| Appearance | White to creamy white powder | Conform |
| Solubility | Slightly soluble in water,freely soluble in 3 N hydrochloric acid, slightly soluble in methanol, practically insoluble in alcohol,in acetone, in chloroform, and in ether. | Conform |
| Identification | IR: The spectrum of sample corresponds to that of the ref. standard. HPLC: The retention time of sample of main peak corresponds to that of the ref. standard. | Conform |
| Specific rotation | -21°～ -23.5° | -21.8° |
| Loss on drying | 6.9% ～ 7.9% | 7.20% |
| Residue on ignition | ≤0.1% | 0.05% |
| Heavy metals | ≤0.001% | ＜0.001% |
| Methyldopa | ≤0.5% | 0.10% |
| Carbidopa related compound A | ≤0.5% | Negative |
| Any other impurity | ≤0.1% | 0.01% |
| Total impurities | ≤1.0% | 0.13% |
| Residual solvents | Should conform | Conform |
| Assay | 98.0% ～ 102.0% | 99.60% |
| Conclusion：Conform with enterprise specification . | ||
Why Choose Us?
Our products have excellent quality and reasonable prices. We are very confident that our price advantage is obvious under the same quality, because we have our own production base, high-quality factories with deep cooperation, and no other intermediaries. You can purchase most of the pharmaceutical intermediates, peptides, and plant extracts. Based on the characteristics of the products and the recent local transportation situation, we will choose a stable shipping company to ensure that the package can arrive safely.
Main applications
The main uses and pharmacological properties of Carbidopa API Powder are as follows:
- Parkinson's disease treatment
As an adjuvant drug of Levodopa, Carbidopa inhibits peripheral dopa decarboxylase activity, reduces the conversion of Levodopa to 3-Hydroxytyramine in the liver and peripheral tissues, thereby enhancing the efficacy of Levodopa entering the brain and reducing peripheral side effects such as nausea and low blood pressure.
- Drug combination
Often combined with Levodopa in a fixed ratio (such as 1:10) to form compound preparations, used to improve motor symptoms (such as tremors, stiffness, and bradykinesia) in Parkinson's disease patients.
- Application of active pharmaceutical ingredients
As a raw material in the pharmaceutical industry, it is used to produce tablets, sustained-release agents, and other formulations.
- Research purpose
In the field of neuroscience, it can be used to study the metabolic mechanism of 3-Hydroxytyramine and the effects of decarboxylase inhibitors in vitro or animal models.
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FAQ
Q1:How Carbidopa works?
A1:In people with Parkinson's disease, the brain lacks sufficient dopamine, When levodopa is taken alone, much of it is broken down in the body's periphery (outside the brain) before it can reach the central nervous system, which causes side effects like nausea.Carbidopa blocks the peripheral breakdown of levodopa by inhibiting the enzyme L-aromatic amino acid decarboxylase (DDC).This allows more levodopa to reach the brain, where it is converted to dopamine, and reduces the risk of side effects.
Q2:What are the Side effects of carbidopa?
A2:Common side effects of carbidopa include:Dyskinesia (uncontrolled, repetitive movements)；Mood and behavior changes, including anxiety, irritability, and depression；Compulsive behaviors such as shopping；Sudden, unexpected drowsiness；Nausea and vomiting；Orthostatic hypotension (dizziness upon standing)；Darkening of urine or sweat.
Q3:Can I place a order via paypal?
A3:Sorry， we don't support paypal currently， Please contanct us to find an appropriate payment method.
Contact Us
If you are conducting Carbidopa API powder related research or formulation production, click Email: sales12@faithfulbio.com to have our high-quality products serve you.
