CAS. NO:5786-21-0
MF.no:C18H19ClN4
EINECS.no:227-313-7
Other names:LEPONEX;LIPONEX;CLOZAPINE;CLOZARIL;COLZARIL;HF-1854;Asaleptin
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place; 36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
" data-aw-url="https://www.faithfulbiochem.com/nootropic-ingredients-powder/clozapine-api-powder/" title="Clozapine API powder">
Clozapine API powder was first synthesized in 1958 and began to be marketed in 1972 as a typical antipsychotic drug. The Clozapine Xi'an Faithful BioTech Co., Ltd provide is an antagonist of the 5-HT2A subunit of the serotonin receptor and can bind to both serotonin and dopamine receptors in terms of efficacy. And further improve depression, anxiety, and negative cognitive symptoms associated with schizophrenia.
The mechanism of action of Clozapine API powder may be to exert pharmacological effects on the central dopaminergic nervous system, selectively blocking dopamine receptors in the midbrain limbic system, with little effect on dopamine receptors in the substantia nigra striatum, thus having strong antipsychotic effects, while extrapyramidal adverse reactions are rare. It also does not rely on the functional activity of adenylate cyclase.
Item | Specifications | Results |
Appearance | Light yellow crystalline powder | Conform |
Odor | Odorless | Conform |
Bulk density | ≥0.20g/ml series product | 0.23g/ml |
Particle size (U.S.mesh) | ≥98% through 80 mesh | Conform |
Appearance of solution | Clear-colorless to light yellow | Conform |
Purity | ≥98.0% | 98.15% |
Water | ≤5.0% | 2.35% |
Ash | ≤1.0% | 0.43% |
Heavy Metals | ≤10ppm | Conform |
Arsenic | ≤0.5ppm | Conform |
Total Plate Count | ≤1000cfu/g | 10cfu/g |
Total Yeast & Mold | ≤100cfu/g | 10cfu/g |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
Conclusion: | Conform with enterprise specification (USP 41). |
Firstly, we appreciate your attention to Clozapine's related information. However, we also understand that when facing critically ill patients such as refractory schizophrenia and their families, it is crucial to have detailed information, usage guidelines, side effect management, and follow-up monitoring requirements for this special medication. Based on this, we are committed to the multiple development and research of Clozapine powder, and currently we can provide you with professional and reliable support and consulting services.
If you or your family members are using or considering API Clozapine and have any questions during the treatment process - whether it's about evaluating efficacy, necessary procedures for blood routine monitoring, or concerns about potential side effects such as granulocyte deficiency, metabolic changes, etc. - our professional team is willing to provide you with assistance and guidance to the best of our ability.
We understand the complexity and challenges of this treatment path, and hope to become your reliable information support with our professional knowledge.
Please note that all medication decisions must be made by professional doctors after a comprehensive evaluation, and the information we provide cannot replace professional medical diagnosis and treatment plans.
Welcome to contact us through the following email, and we will reply to your inquiry as soon as possible.
e-mail address: sales8@faithfulbio.com
We look forward to providing you with assistance and facing challenges together with you.
1. Antipsychotic effect:
Clozapine powder is effective in various acute and chronic mental illnesses, and can alleviate mental symptoms such as excitement, restlessness, hallucinations, delusions, thinking disorders, personality disintegration, and peculiar movements. Scientific experiments have found that the mechanism of action of High purity HF-1854 may be related to blocking dopamine receptors in the midbrain limbic system, but this does not affect dopamine receptors in the striatum, so it rarely produces extrapyramidal reactions in clinical applications.
2. Sedative and hypnotic effects:
Clozapine can directly inhibit the ascending activation system of the midbrain reticular formation. Research has shown that low doses of COLZARIL raw material can inhibit spontaneous activity, while high doses can increase spontaneous activity.
3. Anticholinergic, antihistamine, and anti hormonal effects:
Clozapine API powder has a strong anti acetylcholine effect and also blocks histamine and body secreted stimulating hormones.
Q1.:What modes of transportation do you have to choose?
We cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.
And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.
Q2.:How long does it take to the goods arrived ?
It is Depending on your location:
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, HKEMS,Netherlands post.
For large order, please allow 5-8 days by Air, 20-35 days by Sea
At the same time, we have warehouses in Germany and California, and some orders can be sent directly from Germany or California.
Q3.: From where you send goods?
We send goods from Hong Kong, ShenZhen or Shanghai. Goods are packed very well.
If you have any questions about the treatment plan, blood concentration monitoring, or side effect management of Clozapine API powder, our professional team is willing to provide you with consultation and support. Please be aware that specific medication must be taken according to medical advice.
Welcome to contact us through the following email: