Metoclopramide is a dopamine D2 receptor blocker, which can block the D2 receptor in the chemical emetic receptor area (CTZ) of the medulla oblongata and produce a powerful central antiemetic effect. Clinically, it is often used to treat vomiting caused by various reasons. Metoclopramide powder provided by Xi'an Faithful BioTech Co., Ltd. can be used to treat migraine and repair the external environment of nervous system in addition to producing products for treating stomach and esophagus problems.
Metoclopramide powder is a central and peripheral D2 receptor antagonist, which has 5-HT4 receptor agonist effect, slightly inhibits 5-HT3 receptor, and has strong central sedative and antiemetic effects. Clinically, he mainly deals with symptoms such as nausea, vomiting and various abdominal discomfort caused by various reasons. According to the relevant scientific literature, the core function of metoclopramide API powder is to achieve the effect of stopping vomiting and promoting digestion by inhibiting vomiting center of brain and enhancing gastrointestinal peristalsis.
1. Central antiemetic effect: It can block the dopamine D2 receptor in the chemoreceptor trigger zone (CTZ) in the brain. CTZ is the key area to control vomiting. When it is stimulated (such as drugs, toxins, diseases), it will cause nausea and vomiting. 98% purity Metoclopramide directly inhibits the vomiting impulse by blocking the receptor here.
2. Peripheral motivity: It can enhance the peristalsis of gastrointestinal tract, accelerate the emptying of stomach and the speed of food passing through small intestine. This is very effective in treating abdominal distension and belching caused by insufficient gastric motility (such as diabetic gastroparesis).
Item | Specifications | Results |
Appearance | White or off-crystalline powder | Complies |
Odor & Tasted | Characteristic | Complies |
Identification | The retention time of the major peak in the chromatogram of sample corresponds to that in the chromatogram of standard preparation | Complies |
Particle Size (20nm) | ≥99.8% | Complies |
Loss on drying | < 2.0% | 1.47% |
Ash | < 1.0% | 0.15 |
Heavy Metal | ≤10 ppm | 1.1ppm |
Pb | ≤1.0 ppm | 0.3ppm |
As | ≤1.0 ppm | 0.8ppm |
Hg | ≤0.1 ppm | Negative |
Cd | ≤0.1ppm | Negative |
Total Plate Count | ≤ 1000cfu/g | 28.31 cfu/g |
Total Yeast & Mold | ≤ 100cfu/g | 0.25 cfu/g |
E.Coli | ≤ 1cfu/g | Negative |
Salmonella | ≤ 1cfu/g | Negative |
Assay (HPLC) | 99%-101% | 99.68% |
Conclusion: | Conform with enterprise specification (USP 41). |
In today's complicated medical market choices, you may ask: Why do you choose the metoclopramide products we provide? Our answer lies in its irreplaceable dual-action mechanism, remarkable curative effect that has stood the test of time, and excellent cost-effectiveness under strict norms. The products we provide are not suitable for everyone, but in specific clinical scenarios, we provide unique and critical value.
Different from single-function drugs, metoclopramide acts on two key links: the central part and the gastrointestinal part at the same time. Clinically, the Metoclopramide hydrochloride provided by us ensures that it can provide an immediate solution and greatly reduce the pain of patients under the complicated situation that the symptoms need to be controlled quickly and the motivation needs to be improved.
Since the establishment of our company, the efficacy of metoclopramide provided by us has been confirmed in countless clinical cases around the world. Customers who have used our products have high comments on this:
1. The curative effect is clear: within the scope of indications, our antiemetic and prokinetic effects are rapid and significant.
2. Predictable effect: Its pharmacokinetic and pharmacodynamic characteristics have been fully studied, which provides accurate dose adjustment basis for doctors, especially in the management of hospitalized patients.
3. This long-term and extensive clinical experience has built the confidence and grasp of doctors when using our products.
The raw materials of metoclopramide powder we provide have been continuously verified by the production market, and customized modules have been established according to the market, so we are confident that our products are also the best choice for your company to make various dosage forms, and this flexibility enables our products to seamlessly adapt to various production scenarios from laboratories to factories.
Metoclopramide provided by us has obvious economic advantages on the premise of ensuring the same curative effect. This greatly reduces the treatment cost for the medical system and individual patients, making effective treatment more accessible, especially suitable for a wide range of people who need short-term and intensive treatment.
Therefore, our commitment to your company is:
1. Clear positioning: metoclopramide is not a panacea, nor is our factory a panacea, but the first choice among your short-term and powerful solutions. We clearly emphasize that the use effect of the products we provide is in full compliance with the provisions of the Pharmacopoeia.
2. Professional partnership: We always insist on cooperation with schools and large and medium-sized hospitals in China. Actively collect effective solutions provided by professionals in production to ensure maximum benefits and minimum risks.
3. Continuous exploration: We are committed to providing our partners with the most comprehensive and objective information, ensuring that every use is an informed and rational choice, and providing a solid theoretical foundation for your next breakthrough.
When you are faced with the challenge that you need to control nausea and vomiting quickly and effectively without enhancing gastrointestinal motility at the same time, please consult Metoclopramide API powder for specific quotation and preferential scheme by email. Our email address is: sales8@faithfulbio.com.
The most important side effect of Metoclopramide powder is extrapyramidal reaction, which is most likely caused by the inhibitory effect of Metoclopramide on brain nerves. According to clinical statistics, such symptoms include but are not limited to
1. Acute dystonia: sudden neck torsion, upturned eyes, facial muscle spasm, closed teeth, difficulty in speaking and swallowing, etc.
2. akathisia: I am extremely agitated, unable to sit still and keep pacing.
3. Symptoms similar to Parkinson's disease: muscle stiffness, tremor and slow movement.
In case of any of the above symptoms, please use Metoclopramide immediately and seek medical advice.
Interested in enhancing your product line with premium, high-purity Metoclopramide Powder? Our expert team is ready to understand your specific needs for nootropic ingredients and provide tailored solutions that deliver a distinct market advantage.
Choose Xi'an Faithful as your trusted partner for a seamless partnership backed by reliable supply chain expertise. We invite you to contact us and start a conversation about your next project.