Raw material Tadalafil powder
CAS. NO: 171596-29-5
MF.no:C22H19N3O4
Other names:GF 196960;ICOS 351;Tildenafil;UK 336017;TADALAFIL;CIALIS;IC 351;Tadalafil;Tildenafil;Calais
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place; 36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Raw material Tadalafil powder Manufacturer & Supplier
Raw material Tadalafil powder is a reversible, selective phosphodiesterase-5 inhibitor (PDE5), which is a powerful, long-acting, reversible PDE-5 inhibitor with pulmonary vascular selectivity. It can significantly increase NO levels and dilate pulmonary blood vessels. Xi'an Faithful BioTech Co., Ltd. provides Tildenafil with minimal visual impact. On older large mammals, it was found that it does not affect the production of sperm or hormone secretion within 6 months.
Raw material Tadalafil powder Introduction
Although Raw material Tadalafil powder is also a selective type 5 phosphodiesterase (PDE5), its structure is different from conventional products, resulting in almost no interference with its absorption in high-fat diets. We know that under sexual stimulation, a series of biochemical reactions occur in the nerve endings and endothelial cells of the penis, causing the conversion of guanosine triphosphate into cyclic guanosine monophosphate (cGMP) in the body, thereby activating the cyclic guanosine monophosphate dependent protein kinase, leading to a decrease in calcium ion concentration in smooth muscle cells, causing the smooth muscle of the corpus cavernosum of the penis to relax and achieve erection. And the type 5 phosphodiesterase (PDE5) in the body degrades cGMP into a physiologically inactive product, so the scientific community generally believes that Calais powder inhibits PDE5 degradation, leading to the accumulation of cGMP and maintaining the results of sexual stimulation.
Specifications
Item | Specifications | Results |
| Appearance | White or almost white powder | Complies |
Solubility | Practically insoluble in water, freely soluble in dimethyl sulfoxide, slightly soluble in methylene chloride | Complies |
Identification | IR,UV | Positive |
Impurities A, B and C | Specified impurities: ≤0.10% | Complies |
IR | IR should comply with the reference standard spectrum. | Complies |
relative substance | positive | Complies |
| Total impurity: ≤0.3% | 0.17% |
Loss on Drying | ≤0.5% | 0.20% |
Sulfated ash | ≤0.1% | 0.06% |
Heavy Metals | ≤20ppm | Complies |
Relevant Impurity | ≤0.5% | 0.28% |
Methanol | ≤0.3% | 0.021% |
Methylene dichloride | ≤0.06% | 0.017% |
N,N-Dimethyl formamide | ≤0.088% | Not detected |
Assay (on dried basis) | 97.5%~102% | 99.57% |
| Conclusion： | Conform with enterprise specification （USP 41）. |
Why Choose Us?
When choosing a supplier of Tadalafil API powder, what you need is not only the product, but also a strategic partner who can ensure the stability of your supply chain and product competitiveness.
1. Excellent quality, reliable cornerstone
We provide high-purity Tadalafil powder (purity ≥ 99.5%) that strictly follows USP/EP pharmacopoeia standards, and is equipped with complete CoA and other compliance documents, laying a solid foundation for the safety and effectiveness of your formulated products.
2. Collaborative advantages and potential for expansion
By choosing us, you will gain collaborative value beyond a single product. We also supply PDE5 inhibitor raw materials such as Apremilast and vardenafil, as well as their key intermediates. This provides a one-stop, efficient solution for developing composite formulations or enriching product lines, significantly optimizing your supply chain.
3. Professional support, co creating value
We are committed to becoming your technical support, providing professional support throughout the entire process from raw materials to production.
Contact us immediately (email:sales8@faithfulbio.com) to obtain an exclusive quote for Raw material Tadalafil powder and explore how our complete product portfolio can create more value for you.
Interaction
Raw material Tadalafil powder affects by inhibiting PDES. GMP degradation may cause extreme blood pressure drop and increase the risk of fainting when used in combination with nitrate vinegar api powder. CY3PA4 inducer reduces the bioavailability of Tadanafil, and Rifampicin、Cimetidine、Erythromycin、Clarithromycin、Itraconazole、Ketoconazole、HVI The combination of protease inhibitors and other product may increase the blood concentration of it, and attention should be paid to adjusting the dosage. So far, there have been no reports on the influence of diet and alcohol on pharmacokinetic parameters.
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FAQ
Q1:What is the purity of the Tadalafil powder you provided? What standards do they meet ?
The purity of the Tadalafil powder we provide is stable at 99.5% or above, strictly following and complying with the standards of major international pharmacopoeias such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and CP (Chinese Pharmacopoeia). Each batch of products comes with a detailed analysis certificate for verification.
Q2: Can you provide detailed quality control documents ?
Of course. For each shipment, we will provide a complete analysis certificate, which includes but is not limited to key data such as HPLC purity, related substances, moisture, residual solvents, heavy metal content, and microbial limits. We can also provide stability study data, MSDS and other documents as required to fully support your registration and declaration work.
Q3: How to ensure the stability and shelf life of Raw powder Tadalafil ?
We conducted strict long-term stability tests and accelerated stability tests to determine the retesting period of the product (usually 24 months or longer). We recommend storing the product in a cool, dry, and dark place to ensure stable quality throughout its entire shelf life.
Contact us
In the field of raw material intermediate development, choosing suppliers means choosing responsibility and trust. We promise that we will use our professionalism, integrity and quality to provide you with top-notch Raw material Tadalafil powder, which will become the most solid and trustworthy link in your supply chain.
Whether you are developing new products or expanding production scale, we are ready.
Please contact us immediately (our email address is sales8@faithfulbio.com) to get the latest product information, CoA samples and competitive quotations.
