Unifiram powder
CAS. NO:272786-64-8
MF.no:C13H15FN2O3S
EINECS.no:1532714-185-1
Other names:Unifiram;DM232;DM-232
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place; 36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Unifiram powder Manufacturer & Supplier
Unifiram powder can induce a lasting increase in the amplitude of field-excited postsynaptic potential (fEPSP) in hippocampal CA1 region of rats (EC50= 27 nM), and increase the release of acetylcholine (ACh) in cerebral cortex of rats. Unifiram powder provided by Xi'an Faithful BioTech Co., Ltd. is a powerful cognitive enhancer, and its efficacy is four orders of magnitude higher than that of piracetam. Although these compounds do not show affinity in the study of binding with the most important central receptors or channels, they can prevent amnesia caused by the regulation of various nerve transmission systems.
Unifiram powder Introduction
Unifiram powder is an nootropic Intermediate raw material. Studies have shown that it can increase the release of acetylcholine (ACh) in the cerebral cortex of rats and induce a persistent increase in the amplitude of field excitatory postsynaptic potential (fEPSP) in the CA1 area of the rat hippocampus (EC 50 = 27 nM). At a concentration of 1 µM, it does not bind to serotonin (5-HT), dopamine or GABA receptors. Unifiram (0.1mg /kg) can improve the memory of non-memory-impaired rats in social learning tests, and at the same time prevent memory deficits caused by AMPA/ sea human glutamate receptor antagonist NBQX. When administered at a dose of 0.01 mg/kg, it can prevent memory deficits caused by anticholinergic products or α 2-adrenergic receptor agonists in mouse passive avoidance tests.
Specifications
Item | Specifications | Results |
Appearance | White to off white powder | Conform |
Odor | Characteristic | Conform |
Melting point | ≥171° | 173° |
Residue on ignition | ≤0.1% | 0.05% |
LOD | ≤0.5% | 0.21% |
Water | ≤1% | 0.03% |
Related Related | Single impurity≤0.5% Total impurity≤1.0% | Conform |
Heavy Metal | ≤10 ppm | ＜10ppm |
Total of bacteria | ≤1000 cfu/g | Conform |
Fungi | ≤100 cfu/g | Conform |
Assay | ≥98.5% | 99.1% |
| Conclusion： | Conform with enterprise specification （USP 41）. |
Why Choose Us?
In the field of cognitive enhancement, choice is more important than anything else. Facing many suppliers, we provide far more than products, but all-round trust and guarantee.
1. Extreme purity: We carry out strict third-party laboratory tests on each batch of Unifiram and Sunifiram, and provide a certificate of purity (CoA) to ensure that the research materials you obtain meet the highest standards.
2. Professional support: We have a professional knowledge team to provide you with professional information about the mechanism and application of drugs to help you make informed research decisions.
3. Reliable logistics: We ensure a stable and transparent supply chain and provide safe and fast global transportation, so that you have no worries.
Based on this, we recommend and provide you with two highly effective cognitive enhancement compounds. Experiments show that both of them can increase the release of acetylcholine from rat cerebral cortex, and also support the hypothesis that AMPA receptors play a role in cognitive enhancement.
1. unifiram: It is famous for its extremely high efficacy (the research shows that its efficacy may be 1000 times that of traditional intelligence drugs), and it is an ideal research object to explore the mechanism of memory formation and neuroprotection. The latest research shows that it can also increase the amplitude of fEPSP in rat hippocampal slices.
2. Sunifiram : A classic acetylcholine substance, which has important research value in improving cognitive clarity and attention.
Choosing us means that you have chosen a partner who will never compromise on quality, knowledge and reliability. We are committed to providing you with the purest and most efficient Unifiram and Sunifiram to help you advance your research safely and effectively.Our email address is: sales8@faithfulbio.com. Welcome to write to us.
Development prospects
Unifiram has been shown in animal studies to have anti-amnesia and other effects, and its efficacy far exceeds that of piracetam. According to relevant literature, it is known that many compounds with related functions have been modified based on this product, such as sunifiram (DM-235) and sapunifiram (MN-19). In addition, Unifiram powder has two enantiomers, among which the dextrorotatory isomer has higher activity. In the future, it is highly likely that structural purification will be carried out to obtain effective components with better effects and fewer side effects. The latest research currently shows that it can shorten the duration of hypnosis induced by certain anesthetic products without compromising motor coordination. Although this product has a good effect and a promising future, it lacks research on human and long-term toxicity. If your company can persist in and solve these problems, it will occupy a place in the market of educational products in the future.
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FAQ
Q1: What is Unifiram?
Answer: Unifiram is a synthetic benzyl piperidine compound and is classified as a "Nootropic drug". It has shown potential as a positive allosteric modulator of the acetylcholine system in preclinical studies, with extremely strong cognitive enhancement activity (it is claimed that its efficacy is about 10,000 times stronger than that of piracetam). At present, it is only used for scientific research and has not been approved as a drug by any country's drug regulatory authority.
Q2: What are the main research purposes of Unifiram?
Answer: In the legal field of scientific research, Unifiram powder is mainly used for:
Neuroscience research: Exploring its mechanism of action, especially its impact on AMPA receptors and the cholinergic system.
Cognitive function research: Studying its potential enhancing effects on learning, memory and attention in animal models.
Analytical method development: As a reference material, it is used for the development and analysis of detection methods for Unifiram content in biological samples (such as HPLC-MS/MS).
Q3: What is the relationship between Unifiram and Sunifiram?
Answer: Unifiram is a structural analogue of Sunifiram (an investigational intellectual drug). It is believed that Unifiram is more potent than Sunifiram, but their mechanisms of action are similar. They all belong to research-grade experimental compounds.
Q4: How pure is the product? Is there an analysis certificate?
Answer: The Unifiram powder we provide is of high purity specification (usually ≥98% or higher). Each batch of products will be accompanied by an independent analysis certificate, which details the data such as purity, moisture content, residual solvent and impurity content determined by high performance liquid chromatography and other methods.
Q5: How to place an order? What is the minimum order quantity?
Answer: You can contact us via email (e.g. sales8@faithfulbio.com) for inquiries and orders. We offer flexible packaging ranging from grams to kilograms, with a minimum order quantity usually of 1 gram. The specific price depends on the order quantity.
Q6: Can samples be requested for testing?
Answer: Yes. For qualified research institutions or potential partners, we can provide a small number of samples for quality verification (for example, through Fourier transform infrared spectroscopy or HPLC analysis). For sample policies (such as whether they are free or not), please consult our sales team directly.
Q7: How are the products packaged and transported?
Answer: To ensure the stability and safe transportation of the product, we adopt standard packaging
Inner packaging: Sealed aluminum foil bags or glass bottles.
Outer packaging: discreet corrugated cartons.
We ship through reliable express delivery services and provide tracking information.
Q8: How to store?
Answer: It should be stored in a cool, dry and dark place. It is recommended to keep it refrigerated at 2-8°C. The packaging containers must be kept sealed to prevent moisture and contamination.
Inform us
If you are interested in obtaining the high-purity raw powder of Unifiram powder and Sunifiram powder provided by us, it will lay a solid foundation for your scientific research.
Please contact us: sales8@faithfulbio.com (e-mail)
It would be our pleasure if we could support you.
