CAS NO.: 120287-85-6
structural formula:C70H92ClN17O14
EINECS.no:686-384-6
English alias:Cetrorelix;Cetrorelixum;CETRORELIX ACID;Cetrorelix acetate
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents." data-aw-url="https://www.faithfulbiochem.com/steroid-raw-powder/cetrorelix-acetate-api-powder/" title="Cetrorelix Acetate API powder">
High-quality Cetrorelix Acetate API powder is a synthetic decapeptide, which is mainly used in assisted reproductive technology to prevent premature ovulation for patients with controlled ovarian stimulation. Xi'an Faithful BioTech Co., Ltd. produces Cetrorelixum in strict accordance with the new technology of solid-phase synthesis. According to the experimental data of related ovarian stimulation, the action time of CETRORELIX produced by us is dose-dependent. It is estimated that the inhibitory effect of Cedric is at least 4 days after a single administration of 3mg, and the inhibitory effect is about 70% on the fourth day. Repeated administration of 0.25mg CETRORELIX ACID every 24 hours can maintain its effect.
CETRORELIX ACID is an antagonist of gonadotropin releasing hormone (GnRH). GnRH can bind to the membrane receptors of pituitary cells. Cetrorelix Acetate API powder can competitively bind these receptors with endogenous GnRH, thus inhibiting the secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) by adenohypophysis in a dose-dependent manner, delaying the appearance of LH peak, and thus controlling ovulation. It should be noted that,The effect of Xi'an Faithful BioTech Co., Ltd is dose-dependent, the inhibition is direct, and it is maintained through continuous treatment, without causing the activity of luteinizing hormone receptor to increase at the beginning and then decrease.
Item | Specifications | Results |
Appearance | White or almost white powder | Conforms |
Molecular Ion Mass | 6221.96724 | Conforms |
Purity (HPLC) | > 98.0% | 99.17% |
Related substances (HPLC) | Total impurities:< 2.0% Maximum single impurity: < 1.0% | 0.88% 0.28% |
Acetic acid Content (HPLC) | < 15.0% | N.D |
TFA Content (HPLC) | < 1.0% | N.D |
Water Content (K.F) | < 8.0% | 6.63% |
pH | Reported value(C=5mg/ml) | 8.50 |
Residue solvents(GC) | Acetonitrile < 410ppm Methanol < 3000ppm Methylene chloride < 600ppm Isopropyl ether < 5000ppm N,N-Dimethylformamide < 880ppm | 91ppm 26ppm N.D 13ppm N.D |
Oligomer | < 3.0% | N.D |
Bacterial Endotoxins | < 10 EU/mg | Conforms |
Microbial Limits | TAMC< 50 cfu/0.1g TYMC< 50 cfu/0.1g | Conforms Conforms |
Conclusion: | Conform with enterprise specification . |
1: Price competitiveness and cost-effectiveness: We can provide high-quality products at prices lower than the market average through efficient supply chain management and location advantages, truly saving costs for our customers. For example, our company has long-term cooperation agreements with major pharmaceutical laboratories and chemical plants in China. We can not only provide our products at good prices, but also offer you reagents and bulk commercial grade raw materials at discounted prices.
2: Product innovation and quality assurance: Emphasis is placed on material selection and process optimization to ensure durability and user experience. Our product optimization is based on customer feedback and adaptation to new national standards. For new technologies and processes, we first use them on a small scale and then promote them on a large scale to ensure that customers can obtain products of different grades and processes.
3: The overall value of the solution: not only selling individual products, but also providing integrated solutions with better prices (such as puzzle series, enzyme reagent series, etc.), helping customers reduce operating costs and save transaction time.
4: Accuracy of demand matching and service support: The product matrix covers all aspects of production and life, with a repurchase rate far exceeding the industry average, ensuring long-lasting practicality; We also provide 24/7 customer service, rapid response mechanism, and long-term after-sales support.
5: Emotion and personalized value: Integrating environmental protection concepts and brand stories into products to establish emotional connections; Support customized services to enhance users' sense of belonging.
These advantages stem from the company's strong R&D team and resource integration capabilities, ensuring that products stand out in the market and create sustained value for users.If you are interested, please contact me via Email: sales8@faithfulbio.com.
Cetrorelix acetate is a synthetic decapeptide, which is mainly used in assisted reproductive technology to prevent premature ovulation in patients with controlled ovarian stimulation. However, according to the latest research, it has anti-cancer effect. According to reports, the raw material of Cetrorelix, a peptide antagonist of gonadotropin-releasing hormone receptor (GnRHR), which has a Kd value of 0.2 nM, can bind radioactive ligands with mouse LTK cells expressing human GnRHR. On the one hand, It inhibits the activation of hGnRHR and downstream luciferase reporter gene in mice. If the xenotransplantation model of human epithelial ovarian cancer in mice is adopted, Cetrorelixum (60μg/ day) will reduce the tumor volume to 35% of the control, and reduce the serum luteinizing hormone level by 50%. In addition, Cetrorelix acetate can also protect the primordial follicle PMF, with a survival rate of over 65% and a maximum of 86%.
Q1.:What if the package is detained by the customs?
It's rare for this to happen.At the same time, we all have insurance services. You can buy insurance services just in case.We look forward to long-term cooperation with customers, so we are always very careful in product packaging and transportation.
Q2.:How do you treat quality complaint?
First, we will never evade problems and responsibilities, and seek an optimal solution through communication.
Second, If there is a real quality problem caused by us, we will send you free goods for replacement or refund.
Q3:.What is your Return Policy?
Your satisfaction is very important to us. If there are any problems with the product you receive, please contact your account manager within 15 days of receiving of your order. Upon receipt and inspection, Faithful will issue a credit, refund or replacement.
Ready to elevate your peptide products with our premium Cetrorelix Acetate API powder ? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.
Experience the difference of working with a trusted product supplier. Let's build a successful partnership today!