Dermorphin peptide powder
CAS NO.: 77614-16-5
structural formula:C40H50N8O10
EINECS.no:202-853-6
English alias:Dermorphin;DERMORPHIN ACETATE;Dermorphin trifluoroacetate salt;Dermorphin Powder;Dermorphin HAc
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Dermorphin peptide powder Manufacturer & Supplier
Dermorphin peptide powder is a natural heptapeptide isolated from amphibian skin. It is a natural heptapeptide μ-opioid receptor (MOR) agonist, which has a powerful inhibitory effect on neuralgia. The unique structure of DERMORPHIN ACETATE is that it does not contain the N-terminal sequence that makes people mentally dependent, and it is sensitive to naloxone. DERMORPHIN ACETATE produced by Xi'an Faithful BioTech Co., Ltd. is strictly implemented according to national standards, and is mainly used in the surgical rehabilitation of animals in clinic. In addition, our products can often be seen in root canal treatment in hospitals and pain relief on racetracks.
Dermorphin peptide powder Introduction
The amino acid sequence of dermorphin is Tyr-d-Ala-Phe-Gly-Tyr-Pro-Ser-NH2. It inhibits neuropathic pain by activating the μ receptor and exhibits significant blood-brain barrier permeability. In vitro studies have shown an IC50 of 0.72 nM for μ receptors expressed in CHO cells. Further studies have found that the N-terminal tetrapeptide of Dermorphin trifluoroacetate salt is the smallest fragment that maintains activity, but the complete heptapeptide exhibits superior analgesic efficacy. Xi'an Faithful BioTech Co., Ltd. has determined the three-dimensional structure of dermorphin and the δ opioid receptor using cryo-electron microscopy, revealing that its YGGF motif binds to the receptor through an orthosteric pocket, with binding specificity determined by differences in the extracellular end of the receptor. Natural Dermorphin HAc peptide powder was discovered in 1989 from the skin of a South American tree frog.
Specifications
Item | Specifications | Results |
Appearance | White to off white powder | Conform |
Odor | Characteristic | Conform |
Melting point | 157°-159° | 158.3°-158.6° |
Residue on ignition | ≤0.1% | 0.05% |
LOD | ≤0.5% | 0.21% |
Water | ≤1% | 0.03% |
Related Related | Single impurity≤0.5% Total impurity≤1.0% | Conform |
Heavy Metal | ≤10 ppm | ＜10ppm |
Total of bacteria | ≤1000 cfu/g | Conform |
Fungi | ≤100 cfu/g | Conform |
Assay | ≥98.5% | 99.1% |
| Conclusion： | Conform with enterprise specification . |
Why Choose Us?
Our company's Dermorphin peptide powder has the following seven core advantages that are worth considering.
1. With top-notch purity and excellent quality, we offer HPLC purity>98%. The extremely high purity ensures the accuracy, repeatability, and reliability of research results, greatly reducing non-specific effects or experimental interference caused by impurities, saving you valuable time and research funds.
2. Impeccable quality control and transparency, each batch of products comes with a detailed third-party analysis certificate (COA), including HPLC chromatograms, mass spectrometry (MS) analysis data, amino acid composition analysis, sterility testing, and ultra-low endotoxin levels (usually<1 EU/mg). This extreme transparency means you can have complete confidence in the authenticity and quality of the product.
3. Specially designed for scientific research, the product is packaged in sterile, vacuum sealed, light shielded glass bottles filled with inert gases (such as nitrogen) to ensure long-lasting stability and maximum biological activity. Our professional cold chain transportation solution ensures that the products are fully active and undamaged from the factory to your laboratory.
4. We strictly adhere to the principle of "Research Use Only" to ensure compliance, safety, and ethical protection. All production is carried out in cGMP/ISO 9001 certified clean workshops, ensuring that the products are not intended for human use, fully comply with research ethics and international standards, and protect you and your institution from compliance risks.
5. A stable and reliable supply chain, we have independently controlled modern production bases and mature synthesis processes, with strong scale production capacity and sufficient inventory, which can ensure continuous and stable supply, and will never affect your important experimental process due to supply chain interruptions.
6. With professional technical and after-sales support, you not only receive a bottle of powder, but also a professional research support team. We provide detailed product technical documents (TDS, MSDS) and can provide relevant literature support upon request. Our expert team is happy to answer technical questions about product applications, dissolution configurations, and more.
7. Excellent cost-effectiveness and value. Although top-notch quality means high costs, our direct production and scale effect ensure strong market competitiveness under the same ultra-high specifications. A reliable experiment is much cheaper than the cost of experiment failure and data invalidation caused by inferior raw materials. Purchasing our products is a high-value, low-risk investment in your research project.
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Research progress and product preservation of Dermorphin
As mentioned earlier, DERMORPHIN ACETATE is a potent endogenous opioid receptor agonist. It exerts its effects primarily by specifically binding to the μ-opioid receptor (MOR). Experimental studies have shown that upon binding to the MOR, it activates downstream G protein-coupled signaling pathways, inhibiting adenylate cyclase activity and reducing intracellular cAMP production, thereby modulating ion channel activity. For example, inhibiting calcium influx and promoting potassium efflux leads to neuronal hyperpolarization, reducing neurotransmitter release, and ultimately producing a range of effects, including analgesia, respiratory depression, and euphoria. Current research on dermorphin focuses on its potential as a novel analgesic and its mechanism of action in neuroscience. Because Dermorphin peptide powder has high affinity and selectivity for the μ-opioid receptor, it holds promise for the development of analgesics that are more effective and less nociceptive than traditional analgesics. In the field of neuroscience, studying the modulatory effects of dermorphin powder on neuronal activity and neurotransmitter release will provide a deeper understanding of physiological processes such as pain perception and mood regulation. Furthermore, structural modification of Dermorphin trifluoroacetate salt to synthesize analogs with improved pharmacokinetic properties is also a current research hotspot.
Due to the large number of research needs, dermorphin powder requires extreme care in storage, keeping it dry and protected from light. It can be stored at 0-4°C for short-term storage, while -20°C is recommended for long-term storage. Furthermore, due to its high water solubility (and its high solubility in polar solvents such as methanol and ethanol), it is typically stored in solvent in laboratories.
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FAQ
Q1: What do you do? What products do you have?
xi'an faithful supplies Nootropic ingredients powder, bodybuilding supplements pharmaceutical intermediates (Such as Men's health ingredients, Cosmetic ingredients, Hair care Ingredients, Weight loss ingredients, Anti-cancer ingredients, Painkiller ingredients, etc.), Raw materials for animal and plant growth (Such as Veterinary medicine ingredients, Anthelmintics, Synthetic anti-infective materials, Plant growth agent, Herbicide & Fungicide, Insecticide, etc.), Health supplements ( Such as Food additives, Vitamins, Amino acid, Enzyme,ect.), Plant extracts
Q2.：How to contact with you?
When you meet a product you like, you can directly ask about the product you are interested in through the platform, or leave me a message through email. Our email is sales8@faithfulbio.com
Q3.: How is the quality? I want to test.
Before production and extraction, we will test all raw materials.Quality is our top priority.All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.
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Ready to elevate your Peptide products with our premium Dermorphin peptide powder ? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.
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