CAS NO.:75607-67-9
Molecular formula:C10H13FN5O7P
EINECS:616-242-0
Synonyms:Fludarabine (NSC-118218) phosphate;5-Monophosphate
Density:2.39±0.1g/cm3(Predicted
Shelf life: ;24 months
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 10g ,100g
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse" data-aw-url="https://www.faithfulbiochem.com/steroid-raw-powder/fludarabine-phosphate-powder/" title="Fludarabine phosphate powder">
Xi'an Faithful BioTech Co., founded by multiple senior experts in the pharmaceutical industry, has been deeply involved in the research and development of antiviral active pharmaceutical ingredients for 12 years. We use continuous flow chemical synthesis technology to reduce the production cost of Fludarabine phosphate powder by 40% and increase the purity to 99.5%. We provide services to research institutions and corporate clients in multiple countries around the world, making us a reliable partner for you to choose from.
Fludarabine phosphate powder is a chemotherapy drug, also known as Fludarabine. It is a purine analog used to treat certain types of lymphoid malignancies, particularly B-cell chronic lymphocytic leukemia. It works by inhibiting DNA synthesis and killing cancer cells. Quality and consistency are the primary considerations, we strictly control every aspect of the production process to ensure reliable product quality. Fludarabine has high purity and good quality, and supports small orders. This white raw powder product is highly compatible with scientific research or product development needs.
Items | Specification | Result |
Appearance | White or almost white powder | White powder |
Identification By IR | Conforms | Conforms |
Total Impurities by HPLC | 1.5% max | 1.1% |
Water | 3.0%max | 1.2% |
Residual Solvents | 5%.0max | Conforms |
Purity (HPLC) | NLT 98.5% | 99.5% |
Conclusion:Conform with enterprise specification |
Based on product quality
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The following are its main application areas of Fludarabine phosphate powder :
As a first-line or combination therapy, it is used to treat patients with recurrent or refractory CLL, especially when used in combination with Cyclophosphamide (FC regimen) or Rituximab (FCR regimen) to improve efficacy.
For relapsed or refractory B-cell derived NHL, such as small lymphocytic lymphoma (SLL), follicular lymphoma, etc., it is often included as part of chemotherapy regimens.
Often used in combination with other drugs such as Cytarabine and Cyclophosphamide to enhance the therapeutic effect on specific hematological tumors, especially in high-risk or recurrent cases.
Before hematopoietic stem cell transplantation, it may be used to eliminate abnormal cells in the patient's body and create conditions for transplantation.
Exploring the use for mantle cell lymphoma (MCL) or T-cell lymphoma in some studies, but it needs to be determined based on individualized treatment plans.
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Q1: What is the mechanism of action of fludarabine phosphate?
A1: Fludarabine appears to act by inhibiting DNA polymerase alpha, ribonucleotide reductase, and DNA primase, thus inhibiting DNA synthesis. The mechanism of action is not completely characterized and may be multifaceted.
Q2:What are the side effects of fludarabine?
A2: Call your doctor right away if you have a decrease or change in urine amount; joint pain, stiffness, or swelling; lower back, side, or stomach pain; a rapid weight gain; swelling of the feet or lower legs; or unusual tiredness or weakness. Using this medicine while you are pregnant can harm your unborn baby.
Q3:How to purchase this product?
A3: You can contact our account manager, who will provide you with the latest quotation and other relevant details.
Do you need our high-quality product Fludarabine phosphate powder? Don't hesitate, please contact us
Email: sales12@faithfulbio.com
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