Glucagon-like peptide 1 powder

Product words: glucagon-like peptide 1
CAS.NO:89750-14-1
molecular formula:C149H226N40O45
English alias:glucagon-like peptide 1;GLP-1(7-36);GLP-1
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.

Product Description

Xi'an Faithful BioTech Co., Ltd: Your Trusted Glucagon-like peptide 1 powder Manufacturer & Supplier

Glucagon-like peptide 1 powder is a kind of intestinal hormone secreted by human body, which is produced by the action of proglucagon molecule through intestinal proteolytic enzyme. GLP-1 provided by Xi'an Faithful BioTech Co., Ltd. has a variety of physiological characteristics, making it an in-depth research object of potential treatment methods for diabetes. Research shows that our product is qualified for long-term improvement of diabetes patients. Although the decrease of GLP-1 secretion is related to the weakening of incretin in type 2 diabetes patients, further research shows that the secretion of intestinal hormones in type 2 diabetes patients after the use of GLP-1 is no different from that in healthy subjects.

Glucagon-like peptide 1 powder Introduction

glucagon-like peptide 1 powder is an intestinal insulinotropic hormone that can be inactivated by dipeptidyl peptidase 4 (DPP-4). Studies have shown that it stimulates insulin secretion in the body after glucose loading through the intestinal insulinotropic effect. In type 2 diabetes (T2DM), this process may become sluggish or absent; However, pharmacological levels of GLP-1 (7-36) can restore insulin excretion. The scientific community believes that the benefits of this treatment for type 2 diabetes include delaying gastric emptying and inhibiting pancreatic alpha cells from producing glucagon when blood sugar levels are high. In addition, GLP-1 receptor agonists can reduce pancreatic beta cell apoptosis while promoting their proliferation. Compared with other similar products, Glucagon like peptide 1 raw powder not only reduces systolic and diastolic blood pressure as well as total cholesterol, but also reduces an average weight of 2.9 kilograms. It is currently a well-known experimental product for weight loss research.

Specifications

Item	Specifications	Results
Appearance	White powder	White powder
Solubility	Soluble in water or acetic acid at a to give a clear, colorless solution	Conforms
Identification（MS）	301.3±1.0	299.8
Amino Acid Composition	10% of theoretical	Conforms
Peptide Purity (By HPLC)	≥98.0% by area integration	99.06%
Related Substance(By HPLC)	Total Impurities(%)≤2.0%	0.94%
	Largest Single Impurity(%)≤1.0%	0.58%
Acetate Content (By HPLC)	≤15.0%	12.4%
Water Content(Karl Fischer)	≤8.0%	4.8%
Bacterial Endotoxins	≤5EU/mg	Conform
Peptide Content (N determination)	≥80.0%	81.25%
Assay	95.0～105.0%	98.45%
Conclusion：	Conform with enterprise specification （USP 41）.

Why Choose Us?

Choosing our GLP-1 powder is not just about choosing a raw material, but also about choosing a reliable, efficient, and high-quality partner. The following are the core advantages of our product and the reasons why you should choose us:

1. Excellent product quality and purity
High purity&low impurities: Our GLP-1 API is produced using advanced recombinant DNA technology or solid-phase/liquid-phase synthesis processes, and undergoes strict quality control through cutting-edge analytical techniques such as HPLC and MS to ensure extremely high product purity (usually>99%), with impurity levels such as related substances and residual solvents far below pharmacopoeia standards.

Strict quality system: The entire production process follows cGMP (Dynamic Good Manufacturing Practice) and ISO quality management system, from the source of raw materials to the factory of finished products, every link is strictly verified and controlled to ensure high consistency and traceability between batches.

2. Excellent biological activity and stability
Structural accuracy&activity assurance: We ensure that the product has a completely correct amino acid sequence and spatial structure (such as correct disulfide bond pairing), thereby ensuring its high affinity and excellent biological activity for binding to GLP-1 receptors.

Excellent stability: We ensure the long-term chemical and physical stability of our products during transportation and storage through advanced formulation technology and strict packaging (such as nitrogen filling, light avoidance, moisture prevention), providing a solid foundation for your downstream formulation development.

3. Powerful technical support and customization capabilities
Technical expert team: We not only provide products, but also offer powerful technical support. Our team of scientists can provide you with professional consultation and solutions in formulation development, analytical method validation, regulatory declaration, and other areas.

Flexible customization services: We can provide customized synthesis services for GLP-1 analogs with different specifications, salt types, and even specific sequence modifications according to your research and development needs, to assist in your innovative drug development.

4. Reliable supply chain and scale advantage
Stable supply&strong production capacity: We have independently controlled production bases and mature supply chains, with the ability to produce on a large scale from laboratory level to commercial scale, ensuring uninterrupted supply of raw materials throughout the entire lifecycle from preclinical research to market sales.

Cost effectiveness: Through process optimization and large-scale production, we can provide market competitive prices while ensuring the highest quality, helping you control the overall cost of research and development and production.

5. Complete regulatory support documents
Comprehensive compliance documents: We provide detailed and compliant drug master files (DMF) or a complete set of registration support documents (COA, MSDS, structural confirmation data, process validation data, etc.) that meet the requirements of major global regulatory agencies (such as FDA, EMA, NMPA), greatly simplifying your drug registration and application process and accelerating product launch.

if you need to purchase Glucagon-like peptide 1 powder, please leave me a message. My email address is: sales8@faithfulbio.com

What are the adverse reactions of glucagon like peptide 1?

The most common side effects of GLP-1 agonists include nausea, vomiting and diarrhea, which may lead to acute kidney injury due to volume contraction. In addition, it may appear dizziness, mild tachycardia, infection, headache and indigestion. Patients should know that Glucagon-like peptide 1 powder will increase satiety, and if you try to eat when you feel full, you may have temporary mild nausea. If nausea symptoms appear, the dosage of GLP-1(7-36) should be increased slowly. When used for a long time, the risk of minor hypoglycemia attack is obviously low, but it is still a link that needs attention; If patients develop antibodies to some GLP-1 analogues, it may affect its curative effect, especially when used with Exendin-4.

Quality Control: