LL-37 amide peptide powder

Xi'an Faithful BioTech Co., Ltd: Your Trusted LL-37 amide peptide powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd. is a company mainly engaged in peptides and their upstream and downstream products. Our LL-37 amide peptide powder has a wide range of antibacterial activities. Since its establishment, we have adhered to the corporate philosophy of "using quality as a ship, service as a sail, and scientific research services", providing high-quality services and products for numerous domestic and foreign researchers.

LL-37 amide peptide powder Introduction

There are two main types of antimicrobial peptides produced in the human body: defensive family peptides and cathelicidin family peptides. Although the defensin family of peptides has many members, cathelicidin only has one antimicrobial peptide product, LL-37. LL-37 is the C-terminal cleavage product of cathelicidin peptide Hcap-18, which can directly kill bacteria, fungi, and viruses. It is an antimicrobial peptide derived from an amphiphilic protease with 37 residues. The LL-37 amide peptide powder we produce utilizes advanced equipment, synthesis processes, and purification techniques to obtain high-quality LL-37 with high purity and minimal impurities. It is the preferred raw material for scientific research and production.

Specifications

Why Choose Us?

Strong Strength
The cooperative production base has several well-established peptide production lines, several large-scale peptide synthesis equipment, and imported HPLC analysis and preparation equipment.
Support small-scale trial production
We support low-dose trial orders to meet customers' testing needs for partner compatibility and transportation conditions, reducing their trial and error costs.
Reasonable pricing
We do not win by offering low prices, but we provide you with reasonable quotes at the best quality and set up order discount policies.
Stable transportation
Choose high-quality transportation service providers and ensure the safe shipment of goods through multiple channels and channels.

Main applications

LL-37 amide peptide is an important immune regulatory molecule in the human body with a wide range of biological functions. The following are its main uses and research directions:
1、 Antibacterial and anti infective properties
Broad spectrum antibacterial activity: can directly kill bacteria (such as Gram positive/negative bacteria), fungi, viruses, and some parasites, by disrupting the pathogen cell membrane or interfering with its metabolism.
Enhancing antibiotic efficacy: Combining with traditional antibiotics can reduce the risk of drug resistance, such as synergistic inhibition of methicillin-resistant Staphylococcus aureus (MRSA).
2、 Immune regulation
Inflammation regulation: It can promote inflammatory response (such as recruiting immune cells) and inhibit excessive inflammation (such as neutralizing endotoxins), maintaining immune homeostasis.
Anti autoimmune diseases: Studies have shown that it may alleviate diseases such as rheumatoid arthritis by regulating T cell function.
3、 Organizational repair and regeneration
Promote wound healing: accelerate skin repair, stimulate fibroblast proliferation and angiogenesis, and shorten wound healing time.
Mucosal barrier protection: A protective layer is formed on the surface of mucous membranes such as the respiratory tract and intestines to reduce pathogen invasion.
4、 Antitumor effect
Inhibiting tumor growth: directly inducing tumor cell apoptosis, or enhancing anti-tumor immune response by activating the immune system (such as dendritic cells).
Inhibition of metastasis: Blocking tumor cell invasion and angiogenesis related pathways.
5、 Clinical application potential
Drug development: As a candidate drug, it is used for the treatment of chronic infections (such as diabetes foot ulcers), skin diseases (such as psoriasis) and adjuvant treatment of cancer.
Bioengineering application: By genetically engineering LL-37, a new type of antibacterial agent with strong targeting and low side effects is developed.

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FAQ

Q1:Where is LL-37​​​​​​​?

A1:It is found in neutrophil granulocytes, lymphocytes and monocytes as well as in tissues e.g. squamous epithelium, the lung and the epididymis and is released extracellularly.

Q2:What are the side effects of LL-37?

A2: we found that LL-37 induced apparent rosacea symptoms, erythema, and telangiectasia on the skin. The average erythema area gradually expanded with the increasing number of administered LL-37 injections over 0–10 days.

Q3:What is LL-37 peptide for Candida?

A3: Antimicrobial peptides play important roles in the initial mucosal defense against C. albicans infection. LL-37 is the only member of the human cathelicidin family of antimicrobial peptides and is commonly expressed in various tissues and cells, including epithelial cells of both the oral cavity and urogenital tract.

Contact Us

LL-37 amide peptide powder is high purity peptide，If you have any research or production needs, please feel free to contact us at any time: Email: sales12@faithfulbio.com