Synonym:pramlintide acetate;pramlintide acetate hydrate;AC-137 Acetate Hydrate, SyMlin Acetate Hydrate;Tripo-aMylin Acetate Hydrate;Pramlintide Acetate, Amylin Rat;PramlintideAcetate
CAS NO.:196078-30-5
EINECS NO.:251-228-4
Molecular Formula:C173H273N51O56S2
Purity & Grade: 99%; Medicine grade
Character:White Powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months" data-aw-url="https://www.faithfulbiochem.com/steroid-raw-powder/pramlintide-acetate-powder/" title="Pramlintide acetate powder">
Xi'an Faithful BioTech Co., Ltd. sells Pramlintide acetate powder. Xi'an Faithful BioTech Co., Ltd. Adhering to the concept of "resource conservation, environmental friendliness and green development", a circular economy model is constructed. Xi'an Faithful BioTech Co., Ltd. Attach great importance to environmental protection, actively promote technological transformation for pollution prevention and control, and increase investment in environmental protection. Moreover, we attach great importance to technological research and development, possessing a professional R&D team and advanced R&D equipment, and constantly launching new products and new processes.
Pramlintide acetate powder is an artificially synthesized analogue of human amyloid insoluble peptide (pancreatic amyloid polypeptide), belonging to antidiabetic drugs, and is mainly used for the treatment of diabetes. Pramlintide acetate is co-secreted by pancreatic beta cells along with insulin. It works by slowing gastric emptying rate, inhibiting postprandial glucagon secretion and reducing food intake. These effects complement insulin and help regulate blood glucose concentration.
ltems | Specification | Results |
Appearance | White Powder | Complies |
Identification | Retention time matches reference standard | Complies |
Assay | 99.0%-101.0% | 99.25% |
Water Content(KF) | ≤8.0% | 3.5% |
Acetic Acid Content | 5.0%-10.0% | 7.2% |
Acetate Content | 4.0%-8.0% | 6.1% |
Heavy Metals | ≤10 ppm | <5 ppm |
Microbial Limits | Total Aerobic Count:<1000 CFU/g | <100 CFU/g |
Yeast &Moulds:<100 CFU/g | <10 CFU/g | |
E.Coli Negative | Negative | |
Salmonella Negative | Negative | |
Conclusion | Conform with enterprise specification |
Core application field: Clinical treatment of diabetes
As an artificially synthesized analogue of pancreatic amyloid polypeptide, Pramlintide acetate is an insulin-assisted therapeutic drug, specifically targeting diabetic patients with poor response to insulin alone. It addresses clinical pain points such as "postprandial hyperglycemia", "large blood glucose fluctuations", and "insulin-related weight gain", and is its most important and mature application field.
Extended application fields: Pharmaceutical research and development and scientific research
Based on the characteristics of Pramlintide acetate, such as "clear structure (37-amino acid single-chain polypeptide) and clear mechanism of action", it has significant technical support value in the research and development of polypeptide drugs, drug quality control and basic research on diabetes, and belongs to the extended application of non-clinical treatment.
A1: Pramlintide acetate is an antihyperglycemic drug for use in patients with diabetes treated with insulin. Pramlintide acetate is a synthetic analog of human amylin, a naturally occurring neuroendocrine hormone synthesized by pancreatic beta cells that contributes to glucose control during the postprandial period.
A2: Pramlintide acetate is used with mealtime insulin to control blood sugar levels in people who have diabetes. Pramlintide acetate is only used to treat patients whose blood sugar could not be controlled by insulin or insulin and an oral medication for diabetes. Pramlintide acetate is in a class of medications called antihyperglycemics.
A3: In patients with diabetes, Pramlintide acetate treatment leads to reduction of HbA1c to 0.3–0.7%, decreases body weight and reduces insulin dose. Side effects of Pramlintide acetate powder therapy include nausea, anorexia and hypoglycaemia.
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