CAS NO.: 823202-99-9
structural formula:C19H29N5O3.2(C2H4O2)
EINECS.no:232-697-4
English alias:Dipeptide diaminobutyroyl benzylamide diacetate;SYN-AKE;snake-tripeptide;Snake trippetide;
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate:FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents." data-aw-url="https://www.faithfulbiochem.com/steroid-raw-powder/syn-ake-peptide-powder/" title="Syn AKE peptide powder">
Snake venom-like peptide is a small peptide that mimics the activity of snake venom toxin, not snake venom, but an active peptide with similar structure to snake venom toxin. SYN-AKE has important applications in analgesia, hemostasis, thrombosis inhibition and anti-tumor. In addition, snake-tripeptide is also an important smoothing and anti-wrinkle active product. According to the relevant market data, the Syn AKE peptide powder produced by Xi'an Faithful BioTech Co., Ltd is five times more effective in reducing dynamic wrinkles than that of Botox. Clinical tests show that it can effectively reduce wrinkles by 52% after using this product for 28 days.
SYN-AKE is a substance secreted by the venom gland of venomous snakes. However, due to Snake Trippetide being the most complex class of animal toxins, each snake venom contains at least 20 active ingredients, including various toxins, enzymes, and active peptides. Most of the active ingredients entering the body directly may cause serious toxic side effects, such as cardiotoxicity and neurotoxicity, which limit the clinical application of snake venom preparations. Based on the above issues, Xi'an Faithful BioTech Co., Ltd avoids directly extracting a fragment from animal toxins. Instead, by referring to the microstructure of effective fragments, amino acid small molecules are synthesized into biomimetic peptides that can simulate the mechanism of action of snake venom Waglerin-1 through nanotechnology, and the resulting products are tested for efficacy and toxicity. Practice has proven that synthetic tripeptide Syn AKE peptide powder can antagonize acetylcholine receptors, block nerve conduction signals, inhibit sodium ion release to muscle cells, thereby inhibiting neuromuscular contraction and smoothing/reducing skin wrinkles, achieving the goal of smoothing and removing wrinkles. These have the same effect as naturally extracted snake-tripeptides, and the toxicity and side effects of this product are extremely low.
Item | Specification | Results |
Melting Point | ≥420°C | 422 °C |
Appearance | White to beige powder | Complies |
Identification | In accord CP2010 | Complies |
Related Substances | In accord CP2010 | Complies |
Loss on drying | < 0. 1% | 0.2% |
Residue on | < 0. 1% | 0.04% |
Heavy metals | NMT 10 PPM | Conforms |
Pb | ≤0.5ppm | 0.11ppm |
As | ≤0.5ppm | 0.14opm |
Related substance | Max Single Impurity ≤0.5% | 0.14% |
Total plate count | ≤1,000cfu/g | 3.28 cfu/g |
Mold and Yeast | ≤100cfu/g | 0.12 cfu/g |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
Staphylococcus aureus | Negative | Negative |
Content content | Calculation dry product,C19H29N5O3.2(C2H4O2) 99.0%-101.5% | 99.3% |
Conclusion: | Conform with enterprise specification . |
1: Price competitiveness and cost-effectiveness: We can provide high-quality products at prices lower than the market average through efficient supply chain management and location advantages, truly saving costs for our customers. For example, our company has long-term cooperation agreements with major pharmaceutical laboratories and chemical plants in China. We can not only provide our products at good prices, but also offer you reagents and bulk commercial grade raw materials at discounted prices.
2: Product innovation and quality assurance: Emphasis is placed on material selection and process optimization to ensure durability and user experience. Our product optimization is based on customer feedback and adaptation to new national standards. For new technologies and processes, we first use them on a small scale and then promote them on a large scale to ensure that customers can obtain products of different grades and processes.
3: The overall value of the solution: not only selling individual products, but also providing integrated solutions with better prices (such as puzzle series, enzyme reagent series, etc.), helping customers reduce operating costs and save transaction time.
4: Accuracy of demand matching and service support: The product matrix covers all aspects of production and life, with a repurchase rate far exceeding the industry average, ensuring long-lasting practicality; We also provide 24/7 customer service, rapid response mechanism, and long-term after-sales support.
5: Emotion and personalized value: Integrating environmental protection concepts and brand stories into products to establish emotional connections; Support customized services to enhance users' sense of belonging.
These advantages stem from the company's strong R&D team and resource integration capabilities, ensuring that products stand out in the market and create sustained value for users.If you are interested, please contact me via Email: sales8@faithfulbio.com.
Our company's Snake venom-like peptide powder mimics a small amino acid sequence in Waglerin-1 and undergoes structural modifications, including reducing the peptide chain length to H, lowering basicity and side chain length, and forming a C-amido terminus. This has resulted in a cosmetic peptide that can be safely used to combat expression lines. Furthermore, this product offers the following benefits:
1. Study on SYN-AKE peptide and anti-tumor.
In the research of snake venom drug dosage forms, nanoparticles can deliver snake venom to treat breast cancer more effectively; Combined administration of desert cobra venom and silica nanoparticles can arrest the growth of breast cancer cells by increasing the production of free radicals such as reactive oxygen species (ROS) and hydroperoxide. Moreover, desert cobra venom, whether used alone or in combination with silica nanoparticles, can change the cell cycle by increasing the activities of caspase-8, caspase-9 and caspase-3, which induce apoptosis, leading to the growth stagnation of breast cancer cells and promoting cancer cell apoptosis.
In addition, the protein peptides isolated from snake venom not only have a significant inhibitory effect on the proliferation of human tumor cells, but also can inhibit the abnormal pain during the growth of tumors. Researchers believe that this phenomenon is related to the fact that SYN-AKE powder can inhibit a variety of inflammatory factors and signal pathways. The above studies all point to the powerful anti-tumor effect of snake venom peptide.
2. Study on SYN-AKE peptide and anti-inflammation.
At present, most of the anti-inflammatory drugs used in clinic have obvious adverse reactions, and snake venom components have significant antibacterial activity besides anti-inflammatory effect, and the polypeptide products are highly safe. For example, VIIIa(VRV-PL-VIIIa), a phospholipase A2 component in Agkistrodon halys venom, has membrane permeability bactericidal ability and shows strong antibacterial activity against all human pathogenic strains; In addition, snake-tripeptides produced by some Saudi Arabian snakes (Agkistrodon halys, cobra, etc.) have obvious antibacterial activity against drug-resistant bacteria, which can be developed into drugs for treating bacterial infectious inflammation.
With the development of molecular biology technology, the mechanism of H-β-Ala-Pro-Dab-NHBzl.2AcOH has been gradually clarified. According to the latest research report, Dipeptide diaminobutyroyl benzylamide diacetate plays a pharmacological role by regulating ion channels, regulating cell proliferation and apoptosis, regulating intracellular signal pathways, regulating cytokine expression and binding with related active sites or receptors.
Q1.:When will I receive the shipping number? Where I can check status of my order ?
After the goods are sent out, our staff will send you the shipping number via email, online or WhatsApp ASAP.
You can also check the status online: http://www.17track.net/en
Q2.:Will you reconfirm the product with us before shipment?
Every goods will be labeled, and we will reconfirm with you before the goods are sent out.
Q3.:What if the package is detained by the customs?
It's rare for this to happen.At the same time, we all have insurance services. You can buy insurance services just in case.We look forward to long-term cooperation with customers, so we are always very careful in product packaging and transportation.
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