Vosoritide acetate powder
CAS NO.: 1480724-61-5
structural formula:C176H290N56O51S3
English alias:Vosoritide acetate;vosoritide;Vosoritide;Vosoritide acetate;BMN 111;BMN-111
Test Method:HPLC/UV/GC-MS
MOQ & Package: 10g,100g,1kg,5kg,10kg,25kg etc
Customer's rights and interests:Over 10kg, you can enjoy the service of giving away free samples.
Certificate：FDA,ISO,COA, HPLC, MSDS,TDS etc
Lead Time: 1-3 days
Shipping: DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea,multimodal transport etc
Store & Shelf life; Cool & dry place;36 months
Company advantages: there are self-built overseas warehouses and third-party overseas warehouses on all continents.
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Vosoritide acetate powder Manufacturer & Supplier
Vosoritide (BMN 111) is an improved recombinant CNP (C type C natriuretic peptide) analog, which binds to NPR-B (type B natriuretic peptide receptor) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3). Vosoritide acetate powder produced by Xi'an Faithful BioTech Co., Ltd. is strictly implemented in accordance with national standards, and is mainly used for the study of chondrosis and dwarfism.
Vosoritide acetate powder Introduction
We know that achondroplasia is a genetic disease caused by mutation of FGFR3 gene, which negatively regulates bone growth. While Vosoritide acetate powder provided by Xi'an Faithful BioTech Co., Ltd. stimulates bone growth as a C-type natriuretic peptide (CNP) analogue. Studies have shown that it works by binding with natriuretic peptide receptor B(NPR-B), and enough NPR-B can reduce the activity of fibroblast growth factor receptor 3(FGFR3), thus increasing the linear growth of children with open growth plates. In addition, the Hot sales Vosoritide powder can also stimulate the growth and differentiation of chondrocytes and repair damaged cartilage tissue, which is very friendly to patients with cartilage wear, such as professional athletes.
Specifications
Items | Specifications | Results |
Appearance | White to offwhite crystal fine powder | Complies |
Odor &Tasted | Characteristic | Complies |
Assay(%) | ≥98.0 | 98.65 |
Loss on Drying(%) | ≤0.5 | 0.14 |
Residue on lgnition(%) | ≤0.1 | 0.02 |
Particle size(%) | 100%through 80 mesh sieves | Complies |
Heavy Metal(ppm) | ≤10.0 | 1.38 |
Pb(ppm) | ≤1.0 | Negative |
As(ppm) | ≤1.0 | Negative |
Hg(ppm) | ≤0.1 | Negative |
Cd(ppm) | ≤1.0 | 0.8 |
| Microbiological Tests | ||
Total Plate Count(cfu/g) | ≤1000 | 2.38 |
Yeasts and Moulds(cfu/g) | ≤100 | 0.38 |
E.coli(cfu/g) | Negative | Complies |
Salmonella | Negative | Complies |
| Conclusion： | Conform with enterprise specification . |
Why Choose Us?
As an innovative therapeutic peptide, Vosoritide acetate is one of the first choice drugs for the treatment of Achondroplasia. Compared with other companies, our company's Vosoritide Acetate Powder has the following differentiated advantages:
1. Excellent "clinical grade" quality and consistency, not all suppliers can meet the production standards of API level. Our products strictly follow the cGMP (Chemical Manufacturing Practice) such as ICH Q7, and ensure that the purity (usually more than 98%) and physical and chemical characteristics (such as chiral purity and amino acid sequence) of each batch are very similar and consistent with the original reference preparation. This is very important for generic drug developers to study bioequivalence (BE) or develop new dosage forms.
2. Unparalleled Regulatory Support. Our company can provide a complete set of open/reference rights for drug master documents (DMF) or similar technical documents. This includes but is not limited to:
A detailed set of COA, including HPLC, MS, NMR, peptide map analysis, etc.
Strict impurity mass spectrometry analysis (evaluation of known impurities, unknown impurities, residual solvents and genotoxic impurities).
Process verification and data integrity record.
3. Excellent scale and supply chain reliability. As a long peptide, Vosoritide has complicated synthesis, folding and purification processes. We have stable and scalable production technology from gram level to kilogram level, and can ensure the high consistency of quality between batches of different sizes.
4. Professional technical services and customization capabilities, we provide not only products, but also solutions. The team has profound knowledge of pharmacy and can provide customers with technical advice on prescription development and stability research scheme.
5. Excellent brand reputation and compliance history. In the pharmaceutical field, the audit history and compliance records of suppliers are the gold standard. We have a good international cGMP audit record (such as passing FDA and EU GMP inspection), and all production data are guaranteed to be true, complete and traceable (ALCOA+ principle).
If your company is interested in our products, please leave me a message via email:sales8@faithfulbio.com
What are the application details and precautions of Vosoritide?
Clinically, BMN 111 is mainly used to treat achondroplasia, which is our most common dwarfism. However, special attention should be paid to the fact that its mechanism of action is to increase the linear growth (height) of children with achondroplasia, so the best time to use this product should occur at the age when the growth plate is still open, that is, we usually call children under 18 years old. If it is closed, it only has the function of repairing cartilage, but has no growth function. In addition, Vosoritide acetate is an improved form of endogenous (naturally occurring) C-type natriuretic peptide. Although the safety has increased a lot, Vosoritide will still cause vomiting and blood pressure drop. Therefore, when using it, you should measure your blood pressure regularly, or go to the hospital for re-examination regularly to avoid irreparable consequences.
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FAQ
Q1. : What's your main payment method?
A: T/T (Bank transfer), Western Union, MoneyGram, Wechat,Alipay,Credit card payment etc.
Q2. : Have you received my payment? How long will it take?
Generally, we can receive your payment the next day, and we will inform you as soon as we receive your payment.After confirmation payment, we will send out package
Q3.：When will you sent out the goods after successful payment?
Normally the order will be delivery within 1-3 days after the order confirmed, except the customized products.
Contact Us
Ready to elevate your Peptide products with our premium Vosoritide acetate powder ? Contact our expert team today to discuss your needs and discover how Xi'an Faithful BioTech can support your business growth.
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