Amlodipine base API

Xi'an Faithful BioTech Co., Ltd: Your Trusted Amlodipine base API Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a leading enterprise specializing in the supply of Amlodipine base API, located in Lianhu District, Xi'an City. We provide top-quality pharmaceutical raw materials and intermediates to global customers. We always put customers first and prioritize quality. Currently, our products are exported to Europe, America, Southeast Asia, Australia and other regions, with a customer repurchase rate of over 95%.

Amlodipine base API Introduction

Amlodipine base API is a new generation of long-acting, alkaline dihydropyridine calcium channel antagonists and a representative of third-generation calcium channel antagonists. It, like other dihydropyridine calcium channel antagonists, works through a site (N site) on the cell that is connected to dihydropyridine, affecting the characteristics of calcium channels. We refine our production processes, precisely control the production process, and ensure that the final Amlodipine base API produced meets international standards.

Specifications

Why Choose Us?

We have established a full process quality control system from raw material procurement to finished product delivery. Multiple intermediate testing nodes are set up during the production process to accurately detect key indicators such as purity (≥ 99.5%), related substances, solubility, and stability of raw materials, ensuring stable product quality and small differences between batches.Our team provides 24-hour online service to promptly resolve your doubts and issues.We set reasonable prices for high-quality products and offer tiered pricing and discount policies for long-term cooperative customers or large orders, bringing you more discounts.

Main applications

Amlodipine base is a dihydropyridine calcium channel blocker, and its active pharmaceutical ingredient is the core component for preparing various amlodipine preparations. Its main use is in the treatment of cardiovascular diseases, as follows:

• Treatment of hypertension

This is the main purpose of the Amlodipine base API. It blocks the calcium channels on vascular smooth muscle cells, inhibits the influx of calcium ions, expands peripheral arterial blood vessels, reduces peripheral vascular resistance, and achieves a smooth blood pressure lowering effect. It can be used alone or in combination with other antihypertensive drugs such as diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor antagonists (ARBs), etc.

• Treating coronary heart disease

Used for the treatment of chronic stable angina, it can dilate coronary arteries, increase blood and oxygen supply to the myocardium, while reducing myocardial oxygen consumption, relieving the frequency and severity of angina attacks.
Can be used for vasospastic angina (variant angina), by dilating spasmodic coronary arteries, improving myocardial ischemia, and preventing angina attacks.
For patients diagnosed with coronary heart disease but with normal blood pressure, it can also be used to reduce the risk of cardiovascular events such as myocardial infarction and stroke.

• Preparation of various pharmaceutical preparations

Amlodipine base API is a key raw material for the production of commonly used clinical formulations such as tablets, capsules, and dispersible tablets. Different types of formulations can meet the medication needs of different patients, such as those with swallowing difficulties and those who require rapid onset of action.

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FAQ

Q1:What are the characteristics of Amlodipine base?

A1:Its characteristics are slow onset, long duration of action, convenient administration, and few side effects.

Q2::How Amlodipine base works?

A2It reduces calcium ion influx and inhibits calcium induced aortic constriction twice as much as Nifedipine. Reduce myocardial contractility, slow heart rate, relax vascular smooth muscle, lower peripheral resistance, alleviate cardiac load, and thus lower myocardial oxygen consumption. Amlodipine can also dilate the epicardial and endocardial coronary arteries, increase coronary artery flow, improve blood or oxygen supply to ischemic areas, and alleviate angina caused by coronary artery spasm.

Q3:Is amlodipine safe for kidneys?

A3:Amlodipine is a powerful, well-tolerated, and safe anti-hypertensive agent widely used alone or as a key component of combination therapy for hypertension in chronic kidney disease (CKD).

Contact Us

We have Amlodipine base API. if you need it, pls contact ussales12@faithfulbio.com to get more information.