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Eplerenone API powder

Product Name: Eplerenone API powder
CAS NO.: 107724-20-9
Molecular formula:C24H30O6
EINECS:600-850-8
Synonyms:plerenone
Shelf life: 24 months
Purity : 98% HPLC
Certificate:COA; HPLC; MSDS; TDS,etc.
MOQ : 1g;10g;100g
Shipping: DHL/FedEx/UPS/USPS Safe and fast delivery
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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  • Product Description

Xi'an Faithful BioTech Co., Ltd: Your Trusted Eplerenone API powder Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a high-quality supplier of Eplerenone API powder in the northwest region of China. We always adhere to the corporate spirit of "quality first, customer foremost" and promote the corporate culture of "being humble and doing things with heart", providing customers with high-quality and reasonably priced products. Our clients are located in over 20 countries worldwide. Winning customer recognition through high-quality products and services.

Eplerenone API powder Introduction

Eplerenone is an aldosterone receptor antagonist and potassium sparing diuretic used to treat hypertension. Belonging to mineralocorticoid receptor antagonists, it is a good alternative drug to another typical competitive inhibitor of aldosterone.The appearance is white powder. Our Eplerenone API powder has improved its production process, using advanced production equipment and precise control of reaction conditions to ensure product yield and purity. Can meet the needs of scientific research and pharmaceutical production.

Specifications

Item

Specification

 Results

Appearance

White to almost white powder

complies

Solubility

 complies

 complies

Identification

Similar to standard

complies

Absorbance

NMT0.02 at 420nm(1/20 in methanol)

complies

Water

NMT1.00%

0.52%

Residue on Ignition

NMT0.1%

0.04%

Heavy metals 

NMT20ppm

complies

Related compounds

Impurity A

Total impurities

 

NMT0.1%

NMT1.0%

 

0.06%

0.3%

AssayHPLC)

NLT98.0% and NMT 102.0%

99.6%

Residual solvents by GC

Methanol

Dichloromethane

Acetone

 

NMT 3000ppm

NMT 600ppm

NMT 5000ppm

 

complies

complies

complies

Conclusion:Conform with enterprise standard 

Why Choose Us?

Thank you for your interest in our eplerenone API products. By choosing us, you will receive quality, service, and cost assurance

  • Strict quality control, in line with international standards

Our Eplerenone API powder production process follows the requirements of pharmaceutical raw material birthdays, from raw material procurement, intermediate synthesis to finished product refinement, with multiple testing nodes set up at each step. The purity of the product is stable at over 99.5%, and the impurity content is far below the pharmacopoeia limit, which can directly meet the compliance requirements of your formulation research and commercial production.

  • Mature production technology ensures stable supply

Our production base has independently developed efficient synthesis processes, optimized reaction conditions and purification processes, which not only reduce production costs but also achieve large-scale and continuous production. Adequate inventory and stable delivery cycle.

  • Full process collaboration service

The entire team responds 24/7 to promptly resolve any issues you may have during the procurement and usage process.

  • A cost-effective cooperation plan to achieve mutual benefit and win-win results

We can provide highly competitive quotes and offer tiered price discounts and rebate policies for long-term cooperative customers. We are not only raw material suppliers, but also your strategic partners.

Main applications

Eplerenone is a highly selective ALDOSTERONE receptor antagonist. Eplerenone API powder is mainly used for the synthesis of clinical pharmaceutical preparations, with core applications focused on the treatment of cardiovascular diseases, as follows:

  • Treatment of hypertension

As the active ingredient of antihypertensive drugs, Eplerenone blocks aldosterone receptors in tissues such as the kidneys and blood vessels, reducing sodium reabsorption and potassium excretion, lowering blood volume and vascular resistance, thereby steadily lowering blood pressure. It is suitable for the single drug treatment of primary hypertension, and can also be used together with other antihypertensive drugs, especially for hypertensive patients with heart failure and diabetes nephropathy.

  • Treating heart failure

Used to improve the prognosis of chronic heart failure patients with reduced ejection fraction. Aldosterone is overproduced in heart failure, leading to myocardial fibrosis, ventricular remodeling, and increased cardiac dysfunction. Eplerenone can antagonize this process, reducing the mortality rate and risk of hospitalization for heart failure in patients, usually in combination with conventional anti heart failure drugs.

  • Adjuvant treatment for myocardial infarction

For patients with left ventricular dysfunction after myocardial infarction, Eplerenone can reduce the risk of subsequent heart failure and improve long-term survival by inhibiting aldosterone mediated myocardial remodeling.

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FAQ

Q1:What are the advantages of Eplerenone API powder?

A1:The antagonistic effect of aldosterone is strong, and its affinity for androgen and progesterone receptors is extremely low, with minimal adverse reactions and good tolerance.

Q2:Does Eplerenone API powder have hepatotoxicity?

A2:Eplerenone has a small probability of causing an increase in serum transaminase levels, but the degree is usually weak and the duration is short. Currently, there have been no reported cases of heterogeneous liver injury caused by Eplerenone with significant clinical symptoms.

Q3:Can you provide a testing report?

A3:Sure, we can provide COA and MSDS

Contact Us

Are you intrested in Eplerenone API powder? Click here sales12@faithfulbio.com to get more information.

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