Liranaftate API

Xi'an Faithful BioTech Co., Ltd: Your Liranaftate API Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a modern enterprise dedicated to the supply and circulation of pharmaceutical raw materials, deeply cultivating the fields of antifungal and dermatological drug raw materials. We supply high-quality Liranaftate API. Our mission is to connect high-quality drug sources and serve a healthy lifestyle. With a stable supply chain system, strict quality control standards, and professional industry experience, we have become a trusted partner for many customers. The company always adheres to the principles of honest operation and mutual benefit, helping customers seize opportunities in drug research and production.

Liranaftate API Introduction

Liranaftate API is a new type of external antifungal drug raw material for thioamino esters. As an inhibitor of squalene cyclooxygenase, its mechanism of action lies in interfering with the synthesis of ergosterol in fungal cell membranes, disrupting the integrity of the cell membrane, and thus exerting a potent bactericidal effect. The appearance of this raw material is a white to off white crystalline powder, odorless and tasteless, with high fat solubility and good skin penetration. Compared to traditional antifungal drugs, liraglutide exhibits extremely high selective antibacterial activity against dermatophytes (such as Trichophyton, Microsporomycota, and Epidermophyton), especially against Trichophyton rubrum and Trichophyton rubrum, which cause tinea pedis, tinea pedis, and tinea corporis. As a raw material supplier, our Liranaftate API is synthesized using optimized processes, with low impurity content and stable crystal morphology, in compliance with pharmacopoeia standards, and can fully meet the stringent requirements of customers in formulation research and large-scale production.

Specifications

Why Choose Us?

• Firstly, we have the advantage of a direct sourcing supply chain and have established long-term strategic partnerships with top domestic raw material manufacturers, ensuring the continuity and stability of Liranaftate API supply and effectively avoiding the risk of market shortages or significant price fluctuations.
• Secondly, we adhere to the principle that quality is life. Each batch of products undergoes testing and strictly follows the standards of the Chinese Pharmacopoeia to ensure that key indicators such as content, related substances, and residual solvents meet export and domestic sales standards, and complete COA is provided with the goods.
• Finally, we offer flexible and convenient logistics solutions. Whether it's the development and trial of kilogram level small packaging or the commercial production of ton level bulk goods, we can ensure safe and fast delivery to your hands. Choosing us means choosing a trustworthy business partner for the long term.

Main applications

Liranaftate API is mainly used as a drug active ingredient for the preparation of various topical antifungal preparations, with specific uses as follows:

• Clinical treatment medication: mainly used to manufacture drugs for treating superficial fungal infections of the skin, such as athlete's foot (tinea pedis), tinea pedis, tinea corporis, and atopic dermatitis. Its dosage forms include cream, ointment, gel and liniment.
• Compound formulation development: In pharmaceutical research and development, Liranaftate is often combined with other ingredients (such as keratin softeners or glucocorticoids) to develop compound antifungal drugs with synergistic therapeutic effects.
• Addition of daily chemical products: with its characteristics of high efficiency and low toxicity, the original powder has gradually been applied to the research and development of some functional washing and care products (such as medicinal soap, foot care spray) to prevent fungal growth.
• Research and Teaching: As a standard antifungal positive control drug, it is used for in vitro drug sensitivity testing and scientific research and teaching experiments in microbiology, pharmacy, and other fields.

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FAQ

Q1:How Liranaftate works？

A1:By inhibiting the thirty carbon hexaene epoxidation reaction of fungal cells and suppressing the synthesis of ergosterol, a cellular component, antifungal effects are exerted.

Q2:How to synthesize Liranaftate?

A2:5,6,7,8-Tetrahydro-2-naphthol reacted with Thiophenogenes to obtain 5,6,7,8-tetrahydro-2-naphthyl thiochloroformate and 2-methoxy-6-methylaminopyridine. They were reacted in Isopropyl alcohol · water at room temperature for 2 hours to obtain Liranaftate, with a total yield of 70%.

Q3:Which has a stronger antibacterial effect, Liranaftate or Tolnaftant?

A3:The antifungal activity of Liranaftate is 8 times that of Tolnaftant.

Looking forward to working together with you to explore the vast future of the health industry with high-quality Liranaftate API as the cornerstone! If you have any needs, please feel free to inquire at any time: sales1@faithfulbio.com.