Pure 6-Diazo-5-oxo-L-norleucine

Xi'an Faithful BioTech Co., Ltd: Your Trusted Pure 6-Diazo-5-oxo-L-norleucine Manufacturer & Supplier

Xi'an Faithful BioTech Co., Ltd is a high-quality supplier of food supplement - Pure 6-Diazo-5-oxo-L-nurleucine. We provide pharmaceutical intermediates, active pharmaceutical ingredients, small molecule inhibitors, monoclonal antibody products, etc. to the world. Our products are of high quality, low price, and excellent technology. Winning wide customer recognition and high product repurchase rate.

Pure 6-Diazo-5-oxo-L-norleucine Introduction

6-Diazo-5-oxo-L-norleucine is a glutamine antagonist, which was isolated originally from Streptomyces in a sample of Peruvian soil. This diazo compound is biosynthesized from lysine by three enzymes in bacteria.It is one of the most famous non-proteinogenic amino acid. It is a kind of light yellow powder. Our Pure 6-Diazo-5-oxo-L-norleucine Starting from glutamic acid, the reaction process is strictly controlled to obtain raw powder with low impurities and high purity.

Specifications

Why Choose Us?

We have signed a strategic cooperation agreement with top super factories to jointly establish quality control standards and achieve full cycle quality closed-loop management from raw materials to finished product delivery. Our products focus on five major fields: puzzle materials, medical beauty raw materials, peptide synthesis, antibiotic intermediates, and plant extracts, providing customers with a one-stop procurement solution. We provide our customers with a dedicated service team that can quickly respond to their needs within 48 hours. Support a minimum trial order quantity of 100mg, provide customized services simultaneously, and reduce the cost of trial and error for enterprises.

Main applications

The main uses of 6-Diazo-5-oxo-L-norleucine raw powder are:

• Pharmaceutical field

Drug synthesis intermediate: This compound may serve as an intermediate for the synthesis of specific drugs (such as antibiotics, anti-tumor drugs, etc.), used to optimize drug structure or enhance biological activity.

Targeted research: In biochemical research, it may be used to explore inhibitors of specific enzymes or proteins to assist in drug development.

• Research and Analysis

Standard or reference substance: In the laboratory, it may serve as a standard reference for chromatographic analysis and mass spectrometry detection, used for compound identification or quantitative analysis.

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FAQ

Q1:How about solubility of 6-Diazo-5-oxo-L-norleucine?

A1: DON is a water-soluble yellowish powder, which can be dissolved also in aqueous solutions of methanol, or ethanol, but dissolution in absolute alcohols is difficult.

Q2:How it works?

A2: DON is used as inhibitor of different glutamine utilizing enzymes. Due to its similarity to glutamine, it can enter catalytic centres of these enzymes and inhibits them by covalent binding, or more precisely, by alkylation.It could be shown in vitro that DON treatment led to apoptosis, or programmed cell death. Different pathways were investigated; it could be shown that the inner mitochondrial membrane was damaged, and that single strand DNA breaks occurred.

Q3:What are the side effects of 6-diazo-5-oxo-L-norleucine?

A3: Mucitis (83%),diarrhoea (48%),Nausea and vomiting (30%), gastrointestinal bleeding (16% ) and abdominal pain (8% ).

Contact Us

Our food supplement Pure 6-Diazo-5-oxo-L-norleucine is hight quality, if you need it ,pls Email : sales12@faithfulbio.com to get more datail information.