Afatinib API
Synonym: Afatinib API;Afatinib(BIBW2992MA2);GILOTRIF(AFATINIB);850140-72-6
CAS NO.: 850140-72-6
EINECS NO.: 300-004-5
Molecular Formula: C24H25ClFN5O3
Purity & Grade: 99%; Medicine grade
Character: White Powder
Free sample: Available
Stock: In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 5g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
- Product Description
Xi'an Faithful BioTech Co., Ltd: Your Trusted Afatinib API Manufacturer & Supplier
Xi'an Faithful BioTech Co., Ltd. sells high quality Afatinib API. The automation and intelligence of our production process are achieved through the adoption of automated production lines and intelligent control systems. This not only reduces manual intervention and human error risks but also improves production efficiency, allows for accurate production data control, and ensures stable product quality. We aim to create a consumer-trusted brand by virtue of our professional R&D team, strict production processes and high-quality after-sales support. Additionally, the elaborate packaging design of our products, which embodies high-end and fashion senses, helps us gain unique brand recognition in the market.
Afatinib API Introduction
Afatinib API is a quinazoline derivative with amino crotonyl amino substitution, which can be used to treat cancers and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct and gallbladder. Afatinib has also been selected for research purposes in various tumor categories. Afatinib is an irreversible ErbB family blocker that can suppress information transmission and block the main channels related to the growth and division of cancer cells. Since the ErbB family information transduction mechanism can be initiated by multiple homodimers and heterodimers, simultaneously inhibiting multiple ErbB family members (such as EGFR,HER2,ErbB3 and ErbB4) can effectively interrupt downstream information transduction.
COA
| Test items | Specifications | Results |
| Appearance | White Powder | Complies |
| Particle Size | 100%pass 80 mesh | Complies |
| Loss on Drying | ≤5.0% | 2.20% |
| Residue on lgnition | ≤0.1% | 0.05% |
| Na | ≤0.1% | <0.1% |
| Heave Metals | ≤10ppm | 2ppm |
| Pb | ≤3ppm | lppm |
| Total Plate | <1000CFU/g | 100CFU/g |
| Yeast &Mold | <100 CFU/g | 10CFU/g |
| E.Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Assay | ≥99% | 99.35% |
| Conclusion | Conform with enterprise specification | |
Why Choose Us?
All raw material powders are classified by batch, each with a unique "batch code", allowing for reverse inquiries of the production source, inspection data and outbound vouchers. If quality or process issues arise later on, we can efficiently identify the causes to ensure that your production meets compliance requirements.
Quotation transparency is our standard: each quotation includes raw material costs, testing costs and logistics costs, with no hidden fees, helping you precisely control your procurement budget.
For common specifications of raw material powder, we always keep a safety stock (we can also stock up in advance based on your average monthly usage). For urgent orders, "same-day or next-day shipment" can be achieved to prevent production halts due to waiting for raw materials.
Application Areas
Main application: It is used for patients with locally advanced or metastatic non-small cell lung cancer whose tumors carry EGFR exon 19 deletion or exon 21 (L858R) replacement mutation.
Specific mutation type treatment: It can be one of the treatment options for patients with advanced non-small cell lung cancer who have EGFR exon 20 insertion mutations.
Postoperative adjuvant therapy: It is used for patients with stage II-IIIA non-small cell lung cancer who have undergone complete resection and have EGFR-sensitive mutations, as an adjuvant treatment to reduce the risk of recurrence.
Advanced breast cancer: Mainly used for patients with HER2-positive advanced or metastatic breast cancer.
Quality Control:
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FAQ
Q1: What is Afatinib API used for?
A1: Afatinib is used to treat certain types of non-small cell lung cancer that has spread to nearby tissues or to other parts of the body. Afatinib is called kinase inhibitors.
Q2: Is Afatinib API a chemotherapy?
A2: It is important to understand that afatinib is not a traditional chemotherapy product and has a different way of working. It works by targeting the cancer cells to stop them growing and spreading.
Q3: What are the side effects of Afatinib API?
A3: The most common side effects include diarrhea, rash, acne, mouth sores, nail inflammation, dry skin, decreased appetite, nausea, vomiting, and itching.
Contact Us
Choosing our Afatinib API is not only about selecting high-quality raw materials, but also about laying a solid core foundation for the quality of your products and market reputation. You’re welcome to contact us via email: sales9@faithfulbio.com.
Let's work together to turn your goals into reality.
